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Traditional Chinese medicine preparation with antibacterial and liver-protection functions for freshwater fish and preparing method thereof

A technology of traditional Chinese medicine preparation and liver function, which is applied in the field of fish farming, can solve the problems of unreasonable pharmacodynamic tests, insufficient number of diseases, and unknown active ingredients, so as to improve bioavailability, avoid complicated processes, and reduce the amount of traditional Chinese medicine Effect

Active Publication Date: 2019-02-12
河南华牧生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Traditional Chinese veterinary medicine has unreasonable formulas. The formulas become a pile of drugs and cannot be solved. The formulas are generally selected from several flavors for formulating, and then pharmacodynamic experiments are conducted. The pharmacodynamic tests are unreasonable and the number of clinical trials is not large enough. The product has a large amount of addition, unknown active ingredients, unclear mechanism of action, unstable effect, single dosage form, lack of research on toxicological safety, incomplete quality control standards for raw materials and products, etc., poor palatability, inconvenient transportation, and difficult dosage. Control, etc. The development of traditional Chinese veterinary drugs should start from the planting of medicinal materials, involving processing, active ingredients, physiological functions of drugs, and drug toxicity research. It is an urgent problem to be solved in China at present to quickly put it into the application of aquaculture development
[0007] Therefore, it is necessary to explore a compound preparation that can combine multiple physiological functions to solve many problems such as frequent occurrence and recurrent bacterial diseases in intensive farming, decreased fish immunity, and bottlenecks in increasing growth speed.

Method used

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  • Traditional Chinese medicine preparation with antibacterial and liver-protection functions for freshwater fish and preparing method thereof
  • Traditional Chinese medicine preparation with antibacterial and liver-protection functions for freshwater fish and preparing method thereof
  • Traditional Chinese medicine preparation with antibacterial and liver-protection functions for freshwater fish and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] A traditional Chinese medicine preparation with antibacterial and liver-protecting functions for freshwater fish, which is composed of the following raw materials: 50 kg of compound traditional Chinese medicine, 5 kg of antibacterial peptide, 0.5 kg of activated carbon, 1 kg of compound acidifier, 15 kg of thymol, 20 kg of soluble starch, Vitamin C 1 kg, vitamin E 1.2 kg, 50% powder choline chloride 0.04 kg.

[0051] The preparation method comprises the following steps:

[0052] Weigh the antimicrobial peptide, activated carbon, thymol, soluble starch, vitamin C, vitamin E, 50% powder choline chloride, and chlorinate the antimicrobial peptide, activated carbon, thymol, soluble starch, vitamin C, vitamin E, and 50% powder Choline, compound traditional Chinese medicine, and compound acidifier are put into a sterile mixer, stirred for 2 minutes, the stirring speed is 200-240rpm, and the temperature is controlled at 5-8°C to obtain the finished Chinese medicine preparation ...

Embodiment 2

[0054] A traditional Chinese medicine preparation with antibacterial and hepatoprotective functions for freshwater fish, which is composed of the following raw materials: 55 kg of compound traditional Chinese medicine, 4 kg of antibacterial peptide, 0.5 kg of activated carbon, 1 kg of compound acidifier, 15 kg of thymol, 20 kg of soluble starch, vitamin C 1 kg, vitamin E 1.2 kg, 50% powder choline chloride 0.03 kg.

[0055] The preparation method comprises the following steps:

[0056] Weigh the antimicrobial peptide, activated carbon, thymol, soluble starch, vitamin C, vitamin E, 50% powder choline chloride, and chlorinate the antimicrobial peptide, activated carbon, thymol, soluble starch, vitamin C, vitamin E, and 50% powder Choline, compound traditional Chinese medicine, and compound acidifier are put into a sterile mixer, stirred for 2 minutes, the stirring speed is 200-240rpm, and the temperature is controlled at 5-8°C to obtain the finished Chinese medicine preparation ...

Embodiment 3

[0058] A traditional Chinese medicine preparation with antibacterial and liver-protecting functions for freshwater fish, which is composed of the following raw materials: 60 kg of compound traditional Chinese medicine, 2 kg of antibacterial peptide, 0.8 kg of activated carbon, 0.6 kg of compound acidifier, 18 kg of thymol, 29 kg of soluble starch, Vitamin C 2.2 kg, vitamin E 0.9 kg, 50% powder choline chloride 0.05kg.

[0059] The preparation method comprises the following steps:

[0060] Weigh the antimicrobial peptide, activated carbon, thymol, soluble starch, vitamin C, vitamin E, 50% powder choline chloride, and chlorinate the antimicrobial peptide, activated carbon, thymol, soluble starch, vitamin C, vitamin E, and 50% powder Choline, compound traditional Chinese medicine, and compound acidifier are put into a sterile mixer, stirred for 2 minutes, the stirring speed is 200-240rpm, and the temperature is controlled at 5-8°C to obtain the finished Chinese medicine preparati...

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Abstract

The invention relates to the field of fish farming, and particularly relates to a traditional Chinese medicine preparation with antibacterial and liver-protection functions for a freshwater fish and apreparing method thereof. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 50 to 60 parts of compound traditional Chinese medicine, 1 to 5parts of antibacterial peptide, 0.5 to 1 part of activated carbon, 0.5 to 1 part of a compound acidifier, 10 to 20 parts of thymol, 20 to 30 parts of soluble starch, 1 to 3 parts of vitamin C, 0.8 to1.5 parts of vitamin E and 0.03 to 0.05 part of 50% powder choline chloride. The antioxidase and immuno-enzymatic activity of serum can be improved; the liver function is ameliorated; the detoxification of a liver is ensured; the immunity of fed fish can be improved; the morbidity is decreased; and the survival rate is improved.

Description

technical field [0001] The invention relates to the field of fish farming, in particular to a traditional Chinese medicine preparation for freshwater fish with antibacterial and liver-protecting functions and a preparation method thereof. Background technique [0002] The degree of intensification of modern aquaculture is getting higher and higher, including high-density culture in ponds, high-density culture in circulating water, cages and other high-density culture models that cause the decline in the immunity of aquatic animals, especially the frequent occurrence of bacterial diseases. If left untreated for a long time or occurs repeatedly, it will cause great harm to the health of aquatic animals. For the prevention and treatment of bacterial diseases, in addition to improving the breeding environment, enhancing the resistance of aquatic animals, applying microecological agents to preventive water bodies to regulate harmful chemical indicators in water bodies, or taking ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/02A61P31/04A61P37/04A61K36/85A61K31/05A61K31/355A61K31/375
CPCA61K31/05A61K31/355A61K31/375A61K36/19A61K36/47A61K36/481A61K36/539A61K36/708A61K36/718A61K36/756A61K36/81A61K36/85A61K38/02A61P31/04A61P37/04A61K2300/00
Inventor 齐子鑫王新炎郭海涛李生涛李金娥梁文军康海平李连娜
Owner 河南华牧生物科技有限公司
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