Renal insufficiency enema Chinese herbal combination and preparation method thereof

A composition and renal function technology, applied in the directions of drug combination, drug delivery, pharmaceutical formulation, etc., can solve the problem of fundamental improvement of renal function without benefit, and achieve the effect of delaying the process of renal failure, improving diet and reducing complications.

Inactive Publication Date: 2019-02-19
SHANGHAI SEVENTH PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above treatment measures may be helpful in improving the above indicators, they are not beneficial to the fundamental improvement of renal function.

Method used

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  • Renal insufficiency enema Chinese herbal combination and preparation method thereof
  • Renal insufficiency enema Chinese herbal combination and preparation method thereof
  • Renal insufficiency enema Chinese herbal combination and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Weigh 20g of raw rhubarb, 30g of soil tuckahoe, 10g of black medicine, 10g of peach kernel, 30g of saponins, 10g of aconite, and 30g of buliuxing. The aconite and wang buliuxing were decocted, and the first decoction was added with 600ml of water, boiled on a high fire, then decocted with a slow fire for 30 minutes, and the juice was taken for 150m to obtain the anhydride-reducing mixture.

[0018] 1 clinical data

[0019] A total of 50 cases were observed, all of whom were outpatients and inpatients of Shanghai Seventh People's Hospital from January 2017 to June 2018.

[0020] 2 diagnostic criteria

[0021] 2.1 Western medicine diagnostic criteria:

[0022] Meet the diagnostic criteria for early and mid-stage CRF: serum creatinine (SCr) 115-442 μmol / L, glomerular filtration rate (GFR) 15-60ml / min, 24-h urine protein (Upr)>0.2g.

[0023] 2.2 Exclusion criteria: patients aged 70 years old; pregnant or breastfeeding women; those with severe multiple organ damage; those...

Embodiment 2

[0034] 1. Materials and methods

[0035] 1.1 Research objects: 50 patients were all outpatients and inpatients in Nephrology Department of Shanghai Seventh People's Hospital from August 2014 to June 2015. They were divided into 2 groups by random number table method, 25 cases in each group.

[0036] 1.2 Diagnostic criteria

[0037] 1.2.1 Western medicine diagnostic criteria: meet the diagnostic criteria of early and mid-term CRF, serum creatinine (SCr) 115-442 μmol / L, glomerular filtration rate (GFR) 15-60ml / min, 24-h urine protein quantification (Upr)> 0.2g. 1.2.2 Diagnostic criteria of traditional Chinese medicine: refer to the "Guiding Principles for Clinical Research of New Drugs of Traditional Chinese Medicine" promulgated in 2002:

[0038] Main symptoms: (1) fatigue, shortness of breath, lazy speech, lack of appetite, weak waist and knees; (2) nausea and vomiting, heavy limbs; secondary symptoms: abdominal fullness, light mouth without thirst, sticky mouth, infrequent ...

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Abstract

The invention discloses a renal insufficiency enema Chinese herbal combination and a preparation method thereof. The renal insufficiency enema Chinese herbal combination is prepared from materials including 20 g of raw rhubarb, 30 g of rhizoma smilacis glabrae, 10 g of lindera aggregata, 10 g of peach kernel, 30 g of saponin, 10 g of monkshood and 30 g of cowherb seed.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to an enema traditional Chinese medicine composition for treating renal insufficiency and a preparation method thereof. Background technique [0002] Chronic renal failure is a syndrome caused by the decline of renal function in the advanced stage of various chronic kidney diseases. The clinical manifestations are water, electrolyte and acid-base imbalance, as well as a series of poisoning symptoms caused by toxin storage, and the prognosis is poor. While the renal function declines, the body produces adaptation, but this adaptability is limited. When the renal function is damaged by more than 50%, a series of poisoning symptoms and changes in biochemical indicators may appear throughout the body. According to statistics, the annual incidence of this disease accounts for about 0.5 / 10,000 of the natural population. Traditional Chinese medicine believes that renal failur...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K36/896A61P13/12A61K9/00
CPCA61K9/0031A61K36/36A61K36/483A61K36/54A61K36/708A61K36/714A61K36/736A61K36/896A61K36/90A61K2236/331A61P13/12A61K2300/00
Inventor 陈杰郑颖路建饶胡静刘文瑞叶景华
Owner SHANGHAI SEVENTH PEOPLES HOSPITAL
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