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A kind of preparation of Shenling Baizhu powder

A technology of Shenling Baizhu powder and a preparation process is applied in the field of preparation of Shenling Baizhu powder, which can solve the problems of easy oxidation and volatile dispersion of volatile oil, poor fluidity, poor mixing uniformity of powder and the like

Active Publication Date: 2021-08-20
SHAANXI MOMENTUM QIXUEHE PHARMACEUTICAL CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Shenlingbaizhu powder has a lot of medicinal taste, and the ingredients contained in the raw materials are complex, including starch, volatile oil, etc., and the fluidity is poor. During the production process, the mixing uniformity of the powder is not good, and the quality uniformity is difficult to guarantee, which seriously affects the safety of the preparation. and effectiveness; Atractylodes macrocephala tastes bitter and licorice has a special taste, which leads to poor oral compliance of the prepared powder; the main component of amomum in the prescription is volatile oil, but the volatile oil is easy to oxidize and volatilize, and the retention rate is low, which affects the efficacy of the drug

Method used

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  • A kind of preparation of Shenling Baizhu powder
  • A kind of preparation of Shenling Baizhu powder
  • A kind of preparation of Shenling Baizhu powder

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Experimental program
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Embodiment 1

[0027] Embodiment 1 The preparation of Shenling Baizhu Powder of the present invention

[0028] Investigation on Preparation Technology of Composite Particles

[0029] Based on the previous research results and the arrangement of the remaining medicinal materials in the prescription, with the difficulty of crushing as the key factor, licorice, Poria cocos, Atractylodes macrocephala, and Coix seed are classified as difficult-to-crunch medicinal materials except Amomum, yam, ginseng, platycodon grandiflorum, lotus seeds, and white Lentils are classified as easily crushed medicinal materials. The shell-core coating structure was prepared by using amomum seed containing volatile oil and difficult-to-grind medicinal materials as core particles, and easy-to-grind medicinal materials as shell structure.

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Abstract

The present invention provides a preparation method of Shenling Baizhu powder, which comprises the following steps: a, weighing raw materials: ginseng, poria cocos, atractylodes macrocephala, yam, lotus seeds, white lentils, coix seed, Amomum seed, bellflower, licorice; b . Except amomum, divide the raw materials into easily crushable materials and hard-to-crunch materials; c. Make the raw material powders of each component into 10‑100 mesh powders through ordinary pulverizers; d. In a pulverizer, pulverize, then add amomum and hard-to-crunch materials, and pulverize to obtain Shenlingbaizhu powder. The Shenlingbaizhu powder of the present invention, under the particle design technology, the test results of ion mobility spectrum and mouthfeel evaluation show that the oral compliance of the modified powder is improved, the retention effect of volatile oil is good, and it has wettability, content uniformity, Good mobility and other advantages.

Description

technical field [0001] The invention relates to a preparation method of Shenling Baizhu powder. Background technique [0002] As a unique health resource in my country, traditional Chinese medicine plays an important role in disease prevention, treatment and health care. Traditional Chinese medicine is a complex system with the characteristics of multi-component, multi-channel, and multi-target overall action. Compared with chemical medicine, it has quality uncertainty, material basis and production process complexity, quality standards and ambiguity between clinical efficacy. These characteristics increase the difficulty of implementing QbD in production and restrict the development of modernization of traditional Chinese medicine preparations. Taking solid preparations as an example, solid preparations such as pills and powders included in the 2015 Pharmacopoeia account for about 60% of the total TCM preparations, and other preparations account for about 40%. In the prep...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/14A61P1/00A61P1/14A61P3/10A61P13/12A61P15/02A61P17/00A61K36/9064
CPCA61K9/14A61K36/076A61K36/258A61K36/284A61K36/346A61K36/48A61K36/484A61K36/62A61K36/8945A61K36/8994A61K36/9064A61P1/00A61P1/14A61P3/10A61P13/12A61P15/02A61P17/00A61K2300/00
Inventor 史亚军王媚李婧琳邹俊波崔春利张小飞
Owner SHAANXI MOMENTUM QIXUEHE PHARMACEUTICAL CO LTD