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Implantable blood sugar testing probe and screen printing-based manufacturing method thereof

A test probe and screen printing technology, which is applied in the field of sensors, can solve the problems of high cost and complicated production of electrode probes, and achieve the effects of maintaining stability, reducing processing costs, and simple process operation

Active Publication Date: 2019-03-01
ZHEJIANG UNIV +1
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  • Claims
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Problems solved by technology

[0005] The purpose of the present invention is to solve the complex and high cost of electrode probe production in the existing dynamic blood glucose monitoring technology, and to alleviate the discomfort caused by implanted measurement patients, and to provide a blood glucose measurement probe with a new structure and its manufacturing method

Method used

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  • Implantable blood sugar testing probe and screen printing-based manufacturing method thereof
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  • Implantable blood sugar testing probe and screen printing-based manufacturing method thereof

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Embodiment Construction

[0033] The present invention will be further elaborated and illustrated below in conjunction with the accompanying drawings and specific embodiments. The technical features of the various implementations in the present invention can be combined accordingly on the premise that there is no conflict with each other.

[0034] Such as figure 1 Shown is a schematic diagram of the cross-sectional structure of the implantable blood glucose testing probe. The probe is a long needle-shaped multi-layer composite structure, from one side to the other side are anti-adsorption layer 1, slow-release layer 2, insulating layer 4, working electrode layer 5, base layer 6, reference electrode layer 7 , insulating layer 4, slow-release layer 2 and anti-adsorption layer 1. Wherein the insulating layer 4 that is in contact with the working electrode layer 5 has a first uncovered area, the surface of the working electrode layer 5 within the range of this area is not covered with the insulating laye...

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Abstract

The invention discloses an implantable blood sugar testing probe and a screen printing-based manufacturing method thereof and belongs to the field of sensors. The implantable blood sugar testing probeis in a multi-layer composite structure including, from one side to the other side, an anti-absorption layer, a slow release layer, an enzyme layer, an insulating layer, a working electrode layer, abase layer, a reference electrode layer, an insulating layer, an slow release layer and an anti-absorption layer, wherein the insulating layer in contact with the working electrode layer is provided with a first uncovered area inside which the enzyme layer is filled; one side of the enzyme layer is in contact with the working electrode layer, and the other side of the enzyme layer is wrapped and covered by the corresponding slow release layer; the insulating layer in contact with the reference electrode layer is provided with a second uncovered area inside which, instead of the enzyme layer, the corresponding slow release layer is filled. The implantable blood sugar testing probe achieves continuous dynamic measurement of glucose concentration of interstitial and is small and light, and due to the fact of being made of soft materials, can reduce discomfort of users and accordingly have high practical values in the field of implanted blood sugar detection.

Description

technical field [0001] The invention relates to an implantable blood glucose test probe and a screen printing-based manufacturing method thereof, belonging to the field of sensors. Background technique [0002] Diabetes mellitus is a metabolic disease characterized by hyperglycemia caused by defects in insulin secretion in the body or insulin resistance in tissue cells, which can cause cardiovascular diseases, chronic renal failure, retinopathy and other complications. According to the statistics of the International Diabetes Federation (IDF), in 2017, the prevalence of diabetes among adults aged 20 to 79 was 8.8%, and the number of patients has reached 425 million. The number of patients with diabetes in my country is 114 million, ranking first in the world. At present, diabetes cannot be completely cured. Monitoring and controlling the blood sugar concentration of patients can effectively control the disease and reduce the occurrence of complications. [0003] The current...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/26A61B5/1486
CPCA61B5/14532A61B5/14865G01N27/26
Inventor 梁波张思昱陈诗蝶蔡宇王小飞叶学松
Owner ZHEJIANG UNIV
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