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Bidirectional transdermal absorption skincare substrate and preparation method thereof

A two-way effect, transdermal technology, applied in the field of skin care, can solve the problems of affecting the use effect, deposition, damage to the skin, etc., to achieve good skin care effect, accelerate blood circulation, and stable product performance

Pending Publication Date: 2019-04-26
GUANGDONG AUTHENTEA BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Prior art CN108542820A discloses a skin absorption accelerator, skin care matrix and its preparation method and application, but the liposome matrix in the prior art only has one-way transdermal absorption, and the metabolism produced after the essence enters the skin Drugs also need to be slowly excreted from the body through natural mechanisms, which can easily cause deposition under the skin epidermis, affect the use effect, and even damage the skin

Method used

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  • Bidirectional transdermal absorption skincare substrate and preparation method thereof
  • Bidirectional transdermal absorption skincare substrate and preparation method thereof
  • Bidirectional transdermal absorption skincare substrate and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1~9

[0043] A double-acting transdermal absorption skin care matrix, including essence transdermal absorption liposome and dermolyase liposome, wherein the particle size parameters of essence transdermal absorption liposome and dermolyase liposome See Table 1 for details.

[0044] -Table 1

[0045] serial number

Embodiment 10~15

[0047] A two-way transdermal absorption skin care matrix, comprising essence transdermal absorption liposome and dermolyase liposome, wherein the particle diameter of essence transdermal absorption liposome and dermolyase liposome is the same as The same as in Example 1, prepared from the following raw materials: ginger extract, liposome, proppant, antioxidant, solubilizer and stabilizer. The specific mass percentages of each raw material component are shown in Table 2.

[0048] Table 2

[0049]

[0050]

[0051] The preparation method of the bidirectionally acting transdermal absorption skin care base of the foregoing embodiment is:

[0052] S1. Mix lecithin, proppant, solubilizer, and antioxidant at a temperature of 60°C and fully stir until a uniform oil phase is maintained for 15 minutes;

[0053] S2. Dissolve the stabilizer and ginger extract in pure water, heat up to 60°C, stir to form a uniform water phase, and keep warm for 10 minutes;

[0054] S3. Premix the o...

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PUM

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Abstract

The invention discloses a bidirectional transdermal absorption skincare substrate and a preparation method thereof. The bidirectional transdermal absorption skincare substrate comprises an essence transdermal absorption liposome and a skin epitope liposome; the essence transdermal absorption liposome contains a plant extract essence in grain size of 50-200nm; the skin epitope liposome contains a ginger extract in grain size of 200-1000nm. The skincare substrate provided by the invention contains the essence transdermal absorption liposome capable of deeply nourishing skin and the skin epitopeliposome capable of boosting absorption of essence and timely discharging of metabolite and avoiding deposition and skin damage; the bidirectional transdermal absorption of the skincare substrate is realized; the skincare substrate has comprehensive skincare effects of effective nourishing and anti-ageing of whitening agent; the preparation method is simple and easy in operation, is suitable for industrial production and can be widely applied to production of skincare substrate.

Description

technical field [0001] The invention relates to the technical field of skin care, more specifically, to a double-acting transdermal absorption skin care base and a preparation method thereof. Background technique [0002] Liposomes are composed of lipid bilayers, and closed vesicles with a water phase inside are called liposomes. The structure of liposomes is similar to biological membranes, so they are also called artificial biological membranes, with sizes ranging from tens of nanometers to tens of microns , a variety of substances can be wrapped in the water phase and membrane of the liposome. The bilayer membrane structure of liposomes composed of natural membrane components is in principle the same as that of natural cell membranes. Usually, in order to improve the chemical and biological shape of liposomes, liposomes can also be completely composed of artificially synthesized lipids. At present, the research of liposomes is mainly concentrated in four fields: the stud...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/9789A61K8/14A61Q19/00A61Q19/08A61Q19/02
CPCA61Q19/00A61Q19/02A61Q19/08A61K8/14A61K8/9789A61K8/9794
Inventor 周粤生卢泽菁郑胜强梁志朋
Owner GUANGDONG AUTHENTEA BIOTECH INC
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