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An intestinal mitochondrial function protector for relieving heat stress in broilers

A mitochondrial and heat stress technology, applied in the fields of application, animal husbandry, additional food elements, etc., can solve the problems that have not been reported, and achieve the effect of increasing the residence time, improving the level of mitophagy, and alleviating the damage of intestinal mitochondrial function.

Active Publication Date: 2021-08-03
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, so far, studies on the regulation of mitochondrial function through nutritional means are rare, and studies on the improvement of mitochondrial function through regulation of mitophagy have not been reported.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment l

[0019] Preparation: the palygorskite used below is a palygorskite powder with a particle size (200 mesh passing rate) of 92% and a blue absorption of 18g / 100g.

[0020] Take 5 kg of ginkgo biloba extract, 6 kg of chlorogenic acid, 5 kg of betaine, and 10 kg of palygorskite and mix them well to obtain a protective agent of mitochondrial function (Protective agent of mitochondrial function) for relieving heat stress in broilers. Relieving heat stress in broilers, PMFB). The addition amount in broiler feed is 0.05wt.%.

[0021] 105 21-day-old Ross 308 broilers were divided into 7 treatment groups, namely: heat neutral group, heat stress group, ginkgo leaf extract group (heat stress + ginkgo leaf extract), chlorogenic acid group (heat stress + chlorogenic acid), betaine group (heat stress + betaine), palygorskite group (heat stress + palygorskite) and PMFB group (heat stress + PMFB). 15 birds per treatment group. Among them: the temperature of the chicken house in the heat-neut...

Embodiment 2

[0027] Preparation: the palygorskite used is palygorskite powder with a particle size (200 mesh passing rate) of 94% and a blue absorption of 18g / 100g.

[0028] Take 2 kg of Ginkgo biloba extract, 2 kg of chlorogenic acid, 2 kg of betaine, and 5 kg of palygorskite and mix them well to obtain a protective agent of mitochondrial function (Protective agent of mitochondrial function) for relieving broiler heat stress. Relieving heat stress in broilers, PMFB). The addition amount in broiler feed is 0.15wt.%.

[0029]In the experiment, 105 14-day-old AA broilers were divided into 7 treatment groups, namely: heat neutral group, heat stress group, ginkgo leaf extract group (heat stress + ginkgo leaf extract), chlorogenic acid group ( heat stress + chlorogenic acid), betaine group (heat stress + betaine), palygorskite group (heat stress + palygorskite) and PMFB group (heat stress + PMFB). 15 birds per treatment group. Among them: the temperature of the chicken house in the heat-neut...

Embodiment 3

[0035] Preparation: the palygorskite used is palygorskite powder with a particle size (200 mesh passing rate) of 97% and a blue absorption of 24g / 100g.

[0036] Take 8 kg of ginkgo biloba extract, 9 kg of chlorogenic acid, 8 kg of betaine, and 15 kg of palygorskite and mix them well to obtain a protective agent of mitochondrial function (Protective agent of mitochondrial function) for relieving heat stress in broilers. Relieving heat stress in broilers, PMFB). The addition amount in broiler feed is 0.10wt.%.

[0037] In the experiment, 105 21-day-old Avian broilers were divided into 7 treatment groups, namely: heat neutral group, heat stress group, Ginkgo biloba extract group (heat stress + Ginkgo biloba extract), chlorogenic acid group ( heat stress + chlorogenic acid), betaine group (heat stress + betaine), palygorskite group (heat stress + palygorskite) and PMFB group (heat stress + PMFB). 15 birds per treatment group. Among them: the temperature of the chicken house in ...

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PUM

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Abstract

The invention discloses an intestinal mitochondria function protective agent for alleviating broiler chicken heat stress, which comprises: 5-10 parts by weight of ginkgo biloba extract, 6-10 parts by weight of chlorogenic acid, 5-10 parts by weight of betaine, 10-25 parts by weight of palygorskite. Compared with adding Ginkgo biloba extract, chlorogenic acid, betaine and palygorskite alone in the feed, the present invention can significantly alleviate the heat stress of broiler chickens, significantly improve the intestinal mitochondrial autophagy level of broiler chickens under heat stress, and improve the Intestinal mitochondrial function under heat stress in broilers. The four components have a significant interaction in improving the mitochondrial function and mitophagy level of broiler chickens, and have a positive synergistic combination effect. Palygorskite has a controlled-release effect on ginkgo biloba extract, chlorogenic acid and betaine, making it easy to mix with feed to form a uniform dispersion system and easy to use. Through the synergistic effect of each component, the present invention can significantly improve the mitophagy level of broiler chickens under heat stress, and alleviate intestinal mitochondrial function damage caused by heat stress.

Description

technical field [0001] The invention relates to an intestinal mitochondrial function protective agent for alleviating broiler chicken heat stress. Background technique [0002] During modern intensive farming, poultry are often subjected to various stresses, which lead to increased morbidity and stunted growth of poultry. Among the many stress factors, the ambient temperature is particularly important. Poultry is an animal sensitive to heat stress. With the intensification and scale of poultry farming and global warming, the harm of heat stress to poultry has become more and more prominent. Studies have shown that excessively high temperatures can cause a series of symptoms in poultry, such as reduced growth performance, impaired intestinal barrier function, slowed growth in mild cases, decreased resistance, and death in severe cases, resulting in major economic losses. [0003] The intestine is the digestive organ of the body, and it also has endocrine and immune function...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K50/75A23K10/30A23K20/105A23K20/142A23K20/28
CPCA23K10/30A23K20/105A23K20/142A23K20/28A23K50/75
Inventor 胡彩虹王春春冯杰曹舒婷
Owner ZHEJIANG UNIV