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Application of plant extracts in drugs for preventing and treating senile dementia

A plant extract, dementia technology, applied in the field of medicine, can solve problems such as side effects, achieve the effect of regulating qi, no toxic side effects, and nourishing blood vessels

Inactive Publication Date: 2019-06-14
中山市博林树投资管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the drugs for the treatment of senile dementia mainly include cholinesterase inhibitors, cerebral vasodilators, calcium antagonists, drugs to prevent Aβ deposition, drugs that inhibit β and γ secretase, and anti-inflammatory drugs. Long-term use will produce side effects and drug resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The application of a plant extract for the prevention and treatment of senile dementia consists of fruit and vegetable extracts containing fisetin, fig fruit juice extracts containing benzidine, bergamot lactone, and psoralen, and ginkgo flavonoids Ginkgo biloba extract, composed of kudzu root extract containing puerarin; wherein the weight ratio of active ingredients is: 100 parts of fisetin, 10 parts of benzoin, bergamot lactone, psoralen, and 10 parts of puerarin , 10 parts of ginkgo flavonoids are mixed. Combined with an appropriate amount of water to make a drink or compressed into tablets or directly into granules.

Embodiment 2

[0022] The application of a plant extract for the prevention and treatment of senile dementia consists of fruit and vegetable extracts containing fisetin, fig fruit juice extracts containing benzidine, bergamot lactone, and psoralen, and ginkgo flavonoids Ginkgo biloba extract, composed of kudzu root extract containing puerarin; wherein the weight ratio of active ingredients is: 300 parts of fisetin, 100 parts of benzoin, bergamot lactone, psoralen, and 100 parts of puerarin , 100 parts of ginkgo flavonoids. Mixed with appropriate amount of water to make a drink or compressed into tablets or directly into granules.

Embodiment 3

[0024] The application of a plant extract for the prevention and treatment of senile dementia consists of fruit and vegetable extracts containing fisetin, fig fruit juice extracts containing benzidine, bergamot lactone, and psoralen, and ginkgo flavonoids Ginkgo biloba extract, composed of kudzu root extract containing puerarin; wherein the weight ratio of active ingredients is: 150 parts of fisetin, 50 parts of benzoin, bergamot lactone, psoralen, and 500 parts of puerarin , 50 parts of ginkgo flavonoids. Mixed with appropriate amount of water to make a drink or compressed into tablets or directly into granules.

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PUM

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Abstract

The invention discloses application of plant extracts in drugs for preventing and treating senile dementia. The plant extracts comprise a fruit and vegetable extract containing fisetin and a fig juiceextract containing benzaldehyde, bergamot lipoid and psoralen. Senile dementia is believed to be associated with the deposition of amyloid beta protein and tau protein in the brain, and fisetin is asmall active molecule taken orally and can prevent memory loss associated with senile dementia. The fig juice extract containing benzaldehyde, bergamot lipoid and psoralen can make massive harmful proteins capable of causing dementia discharged from the brain and prevent the proteins from being accumulated in the brain. Accumulation of the massive harmful proteins capable of causing dementia in the brain is avoided, and the substances contained in the plant extracts have a significant inhibitory effect on triggering of dementia cells in the brain.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to new uses of known compounds, especially a kind of medicine for preventing and treating senile dementia by using fisetin, benzoxone, bergamot lactone, psoralen and / or ginkgo flavonoids and puerarin application in medicine. Background technique [0002] Alzheimer's disease (AD) is a neurodegenerative disease with insidious onset and progressive development. Clinically, it is characterized by comprehensive dementia such as memory impairment, aphasia, apraxia, agnosia, impairment of visuospatial skills, executive dysfunction, and personality and behavior changes. The etiology is still unknown. Those with onset before the age of 65 are called Alzheimer's disease; those with onset after the age of 65 are called senile dementia. Alzheimer's disease is thought to be associated with the deposition of amyloid-beta and tau proteins in the brain, but mounting evidence suggests that it involves the di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/60A61P25/28A61K31/352
Inventor 叶均毅
Owner 中山市博林树投资管理有限公司
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