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Artificial valved blood vessel

A technology for artificial blood vessels and blood vessels, applied in the field of biomedical engineering, can solve problems such as difficulty and rupture of blood vessel walls, and achieve the effects of preventing deformation, facilitating balloon expansion, and satisfying long-term treatment effects.

Pending Publication Date: 2019-06-21
黄欣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned commonly used artificial valve-bearing vascular prosthesis will encounter great difficulties after the occurrence of stenosis, such as balloon expansion, intravascular stent or re-implantation of interventional valve by percutaneous interventional therapy.
For example, balloon dilation of allograft valved blood vessels and bovine jugular vein valved blood vessels with calcification and stenosis is likely to cause rupture of the vessel wall; artificial blood vessels with artificial valves are difficult due to their structural limitations after the failure of the artificial valve. Interventional valve reimplantation

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] In Embodiment 1 of the present invention, the tissue valve 1 is a complete natural valve with a three-leaflet structure.

[0068] Such as image 3 As shown, the tissue valve 1 is a three-leaflet structure valve 1 with intact structure, shape and function in the treated bovine jugular vein, which is cut at a certain distance along the upper and lower edges of the valve annulus 112 and the vessel wall 113 . Preferably, the distance between the cutting position and the upper and lower edges of the annulus 112 is 3-5 mm. The annulus 112 of the cut tissue valve 1 is still ring-shaped, and the leaflets 111 and the annulus 112 still retain the complete valve structure and function.

[0069] Such as Figure 6 As shown, the artificial blood vessel 2 containing a valve sinus includes a first conduit 201 , a valve sinus 203 and a second conduit 202 , and the valve sinus 203 is located between the distal end of the first conduit 201 and the proximal end of the second conduit 202 ...

Embodiment 2

[0080] In the second embodiment of the present invention, the tissue valve 1 is a valve with a three-leaflet structure made by splicing three tissue leaflets.

[0081] Such as Figure 4 As shown, the tissue valve leaflet 121 with intact structure and shape in the processed bovine jugular vein was cut off at a certain distance along the upper and lower edges of the valve annulus 122 and the vessel wall 123 . Preferably, the distance between the cutting position and the upper and lower edges of the annulus 122 is 3-5 mm.

[0082] The tissue valve 1 is a valve made of three tissue leaflets 121 with the same size, thickness and shape. The tissue leaflets 121 are the leaflets of the tissue valve 1, and the annulus 122 of the three tissue leaflets 121 form a ring shape consistent with the shape of the natural three-leaflet valve annulus, which is the tissue valve 1. of the valve ring.

[0083] The structures and materials of the artificial blood vessel 2 containing valve sinuses ...

Embodiment 3

[0091] Embodiment 3 of the present invention, the tissue valve 1 is a valve with a three-leaflet structure made by splicing three pieces of bovine pericardium.

[0092] Such as Figure 5 As shown, the bovine pericardium slice 131 is a roughly fan-shaped slice cut from processed bovine pericardium slices, the bottom edge of the bovine pericardium slice 131 is 132 , and the top edge is 133 . Preferably, the bovine pericardium slice 131 has a width of 16-38mm and a height of 7-28mm.

[0093] The tissue valve 1 is a valve made of three bovine pericardium slices 131 with the same size and thickness. The main part of the fan-shaped surface of the bovine pericardium sheet 131 is the leaflet of the tissue valve 1, and the bottom edge 132 of the three bovine pericardium sheets 131 forms a ring shape consistent with the valve ring shape of the natural three-leaf leaflet structure valve, namely is the annulus of the tissue valve 1 .

[0094] The structure and material of the artificia...

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Abstract

The invention discloses an artificial valved blood vessel. The artificial valved blood vessel is composed of a tissue valve, an artificial blood vessel with a valve sinus, and an artificial valve support ring, wherein the tissue valve is arranged inside the valve sinus of the artificial blood vessel with the valve sinus, the artificial valve support ring is arranged outside the sinus of the artificial blood vessel with the valve sinus, and the valve ring of the tissue valve and the artificial valve support ring are overlapped in position; the tissue valve, the artificial blood vessel with thevalve sinus and the artificial valve support ring are sutured and connected together with medical sutures. The invention also discloses a preparation method of the artificial valved blood vessel. Theartificial valved blood vessel is an artificial prosthesis more comprehensive in function, higher in durability, easier to obtain, more complete in specification and simpler in implantation and can achieve higher long-term therapeutic effects.

Description

technical field [0001] The invention belongs to the field of biomedical engineering, and relates to an artificial prosthesis, more specifically a prosthesis implanted through cardiac surgery, used for reconstruction or repair of blood vessels from the human right ventricle to the pulmonary artery or from the human left ventricle to the aorta artificial prosthesis. Background technique [0002] At present, there are many technologies applied to artificial valved vascular prosthesis, but there are certain problems in these technologies. [0003] In the 1980s, allografts with valves were used to reconstruct the right ventricular outflow tract with valves, and then problems such as vascular wall and valve calcification, and hemangioma-like expansion were found. At the same time, there are still problems in the allogeneic valve-bearing blood vessels, such as difficult to obtain materials, difficult to match the size, and inconvenient supply. The artificial biological valve or a...

Claims

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Application Information

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IPC IPC(8): A61F2/06
Inventor 黄欣
Owner 黄欣
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