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Pharmaceutical composition with calcium supplement effect, preparation thereof and preparation method thereof

A composition and drug technology, applied in the field of biomedicine, can solve problems such as chronic benzene poisoning, and achieve the effect of ensuring microbial limit, simple process and ensuring stability

Inactive Publication Date: 2019-07-02
HARBIN GLORIA PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Benzoic acid has certain toxicity, and long-term drinking can cause chronic benzene poisoning in humans

Method used

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  • Pharmaceutical composition with calcium supplement effect, preparation thereof and preparation method thereof
  • Pharmaceutical composition with calcium supplement effect, preparation thereof and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The preparation prescription is:

[0033] Calcium gluconate 500g;

[0034] Zinc gluconate 20g;

[0035] Lysine hydrochloride 80g;

[0036] Menthol 1g;

[0037] L-Aspartic Acid 28g.

[0038] The preparation method of the preparation is: take 9000ml of purified water, heat to 100°C, boil, add calcium gluconate, stir and reflux to dissolve it completely, continue to stir and reflux, heat to 100°C, boil, add zinc gluconate, continue to stir and reflux, heat Bring to 100°C, boil, add lysine hydrochloride, continue to stir and reflux, heat to 100°C, boil, stop heating, cool to 40°C-50°C, add L-aspartic acid, cool to room temperature, add menthol, After the solution is evenly stirred, the medicinal liquid is filtered through a microporous membrane into a liquid storage tank and mixed evenly, and purified water is added to 10000ml, and filled to obtain 1000 finished products.

Embodiment 2

[0040] The preparation prescription is:

[0041] Calcium gluconate 700g;

[0042] Zinc gluconate 40g;

[0043] Lysine hydrochloride 120g;

[0044] Menthol 2g;

[0045] L-Aspartic Acid 49g.

[0046] The preparation method of the preparation is: take 9000ml of purified water, heat to 100°C, boil, add calcium gluconate, stir and reflux to dissolve it completely, continue to stir and reflux, heat to 100°C, boil, add zinc gluconate, continue to stir and reflux, heat Bring to 100°C, boil, add lysine hydrochloride, continue to stir and reflux, heat to 100°C, boil, stop heating, cool to 40°C-50°C, add L-aspartic acid, cool to room temperature, add menthol, After the solution is evenly stirred, the medicinal liquid is filtered through a microporous membrane into a liquid storage tank and mixed evenly, and purified water is added to 10000ml, and filled to obtain 1000 finished products.

Embodiment 3

[0048] The preparation prescription is:

[0049] Calcium gluconate 600g;

[0050] Zinc gluconate 30g;

[0051] Lysine hydrochloride 100g;

[0052] Menthol 1.5g;

[0053] L-Aspartic Acid 38g.

[0054] The preparation method of the preparation is: take 9000ml of purified water, heat to 100°C, boil, add calcium gluconate, stir and reflux to dissolve it completely, continue to stir and reflux, heat to 100°C, boil, add zinc gluconate, continue to stir and reflux, heat Bring to 100°C, boil, add lysine hydrochloride, continue to stir and reflux, heat to 100°C, boil, stop heating, cool to 40°C-50°C, add L-aspartic acid, cool to room temperature, add menthol, After the solution is evenly stirred, the medicinal liquid is filtered through a microporous membrane into a liquid storage tank and mixed evenly, and purified water is added to 10000ml, and filled to obtain 1000 finished products.

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Abstract

The invention belongs to the technical field of biomedicine, and particularly relates to a pharmaceutical composition with calcium supplement effect, a preparation thereof and a preparation method thereof. The pharmaceutical composition raw materials are: calcium gluconate, zinc gluconate, lysine hydrochloride, menthol, and L-aspartic acid; the research shows that the pharmaceutical composition ofthe invention has good stability, and the microbial limit inspection accords with pharmacopoeia regulations.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to a pharmaceutical composition with a calcium supplementing effect, a preparation and a preparation method thereof. Background technique [0002] Calcium is the most abundant element in the human body, about 1200 grams, 99% of which form bones, and 1% exists in blood and soft tissues. It is one of the most easily deficient elements in the human body. Cereals and vegetables account for about 90% of the food in the daily diet of Chinese residents. These foods contain a lot of phytic acid, which prevents calcium absorption. Calcium deficiency can lead to many diseases, such as: 1. Night sweats; 2. Easy to wake up and jump; 3. Frequent irritability and crying during the day; The arrangement of the teeth is uneven; 6. The toddler is late; 7. Cramps often occur; 8. The nails are gray or white. [0003] Therefore, the human body should avoid lack of calcium and zinc. A...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/191A61K31/315A61K47/18A61K47/10A61K9/08A61P3/02
CPCA61K9/0095A61K31/191A61K33/30A61K47/10A61K47/183A61P3/02A61K2300/00
Inventor 朱吉满张保华高岩
Owner HARBIN GLORIA PHARMA CO LTD