Anhydrous vitamin A emulsion and preparation method thereof

A technology of vitamin and water emulsion, which is applied in the direction of pharmaceutical formulations, dressing preparations, cosmetic preparations, etc., to achieve the effect of eliminating wrinkles, good anti-oxidation and anti-aging effects, and maintaining skin vitality

Active Publication Date: 2019-08-09
广州市庚晖精细化工有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are two difficulties in the anhydrous system: 1. Replacing the best solvent "water" in nature with "polyol" puts forward higher technological requirements for the solubility

Method used

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  • Anhydrous vitamin A emulsion and preparation method thereof
  • Anhydrous vitamin A emulsion and preparation method thereof
  • Anhydrous vitamin A emulsion and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] This embodiment provides a vitamin A anhydrous emulsion, including the following raw materials in parts by weight:

[0058] 9.5 parts by weight of cyclopentasiloxane, 30 parts by weight of dimethicone crosspolymer, 35 parts by weight of 1,3-propanediol, 15 parts by weight of glycerin, 5 parts by weight of retinyl palmitate 2 parts by weight of ubiquinone, 0.5 parts by weight of lauryl PEG-10 tris(trimethylsiloxy)silylethyl polymethicone, 0.1 parts by weight of squalane, 0.1 parts by weight of resveratrol, Grape seed oil 0.1 weight part, peony seed oil 0.1 weight part.

[0059] Its preparation method is as follows:

[0060] (1) Take cyclopentasiloxane and add it to the main pot;

[0061] (2) Add dimethicone crosspolymer and lauryl PEG-10 tris(trimethylsiloxy)silylethylpolymethicone to the cyclopentasiloxane from step 1 Siloxane, stirred at room temperature until there are no particles, to obtain a mixed solution;

[0062] (3) Clean and disinfect the reaction equipmen...

Embodiment 2

[0066] This embodiment provides a vitamin A anhydrous emulsion, including the following raw materials in parts by weight:

[0067] 62.5 parts by weight of cyclopentasiloxane, 10 parts by weight of dimethicone crosspolymer, 20 parts by weight of 1,3-propanediol, 5 parts by weight of glycerin, 1 part by weight of retinyl palmitate 0.5 parts by weight of ubiquinone, 1.5 parts by weight of lauryl PEG-10 tris(trimethylsiloxy) silylethyl methicone, 0.5 parts by weight of squalane, 0.5 parts by weight of resveratrol, Grape seed oil 0.5 weight part, peony seed oil 0.5 weight part.

[0068] Its preparation method is as follows:

[0069] (1) Take cyclopentasiloxane and add it to the main pot;

[0070] (2) Add dimethicone crosspolymer and lauryl PEG-10 tris(trimethylsiloxy)silylethylpolymethicone to the cyclopentasiloxane from step 1 Siloxane, stirred at room temperature until there are no particles, to obtain a mixed solution;

[0071] (3) Clean and disinfect the reaction equipment,...

Embodiment 3

[0075] This embodiment provides a vitamin A anhydrous emulsion, including the following raw materials in parts by weight:

[0076] Cyclopentasiloxane 9.5 parts by weight, Dimethicone crosspolymer 10 parts by weight, 1,3-Propanediol 35 parts by weight, Glycerin 5 parts by weight, Retinyl palmitate 5 parts by weight 0.5 parts by weight of ubiquinone, 1.5 parts by weight of lauryl PEG-10 tris(trimethylsiloxy)silylethyl methicone, 0.1 parts by weight of squalane, 0.1 parts by weight of resveratrol, Grape seed oil 0.5 weight part, peony seed oil 0.5 weight part.

[0077] Its preparation method is as follows:

[0078] (1) Take cyclopentasiloxane and add it to the main pot;

[0079] (2) Add dimethicone crosspolymer and lauryl PEG-10 tris(trimethylsiloxy)silylethylpolymethicone to the cyclopentasiloxane from step 1 Siloxane, stirred at room temperature until there are no particles, to obtain a mixed solution;

[0080] (3) Clean and disinfect the reaction equipment, then add 1,3-pr...

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Abstract

The invention provides an anhydrous vitamin A emulsion. The anhydrous vitamin A emulsion comprises decamethylcyclopentasiloxane, a polydimethylsiloxane cross-linked polymer, propan-1,3-diol, glycerinum, retinyl palmitate, ubiquinone, lauryl PEG-10 tris(trimethylsiloxy) silylethyl dimethicone, squalane, resveratrol, grape seed oil and peony seed oil. The invention further provides a preparation method of the anhydrous vitamin A emulsion. According to the anhydrous vitamin A emulsion and the preparation method thereof, an alcohol-in-oil system serves as a solvent of cosmetics, inactivation of active ingredients which are easily oxidated or denatured in water can be reduced, and the utilization rate of the active ingredients is increased. By using the natural and safe raw materials, a preservative can be effectively prevented from being used, the safety of the product is improved, and the risk of irritation is reduced; the anhydrous vitamin A emulsion can have good anti-oxidant and anti-aging effects and further can have an effect of brightening the skin color.

Description

technical field [0001] The invention relates to an emulsion and a preparation method thereof, in particular to an anhydrous vitamin A emulsion and a preparation method thereof. Background technique [0002] Water is an indispensable basic raw material in cosmetics; at the same time, it is also the best solvent in nature. Water, as the most important raw material in cosmetics, usually accounts for 60%-80%, or even higher. [0003] However, when water is used as a solvent for cosmetics, chemical modification, microencapsulation or process improvement are usually required for active ingredients that are easily oxidized and attenuated when exposed to water, or polypeptide ingredients that need to be effective within a specific pH range to fulfill. Among them, the safety risk caused by the residual by-products of chemical modification cannot be underestimated; microcapsule encapsulation and process improvement have correspondingly increased the timeliness of product development...

Claims

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Application Information

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IPC IPC(8): A61K8/92A61K8/891A61K8/67A61K8/58A61K8/34A61K8/31A61K8/06A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/922A61K8/891A61K8/585A61K8/345A61K8/31A61K8/347A61K8/671A61K8/06A61Q19/00A61Q19/02A61Q19/08
Inventor 曾宝仪
Owner 广州市庚晖精细化工有限公司
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