Method for preparing butoxyethyl trichloropyridoxoacetate by aqueous phase synthesis method

Abstract

The invention discloses a method for preparing butoxyethyl trichloropyridoxoacetate by an aqueous phase synthesis method, which comprises the following operation steps: (1) adding tetrachloropyridine,sodium hydroxide, water and a catalyst into a high-pressure reaction kettle, carrying out heat preservation reaction, filtering, washing with water, and drying a filter cake to obtain sodium trichloropyridinol; (2) adding sodium trichloropyridinol, methyl chloroacetate and dimethylformamide into a flask provided with a dryer, a condenser, a thermometer and a stirrer, heating the reaction system under stirring, collecting filter cakes and drying to obtain methyl 2-(3,5,6-trichloro-2-pyridyloxy) acetate; (3) adding methyl 2-(3,5,6-trichloro-2-pyridyloxy) acetate, ethylene glycol monobutyl etherand a catalyst into a flask provided with a dryer, a condenser, a thermometer and a stirrer, and obtaining butoxyethyl trichloro-pyridyloxy acetate after reaction treatment. The water phase synthesismethod for preparing the butoxyethyl trichloropyrazolecetate provided by the invention is simple to operate, green and environment-friendly, the starting material is tetrachloropyridine, and the costis lower.

Description

technical field [0001] The technical field of preparation of chemical herbicides of the present invention particularly relates to a method for preparing triclopyroxyethyl butoxyethyl ester by an aqueous phase synthesis method. Background technique [0002] Pyroxypyr (cap irrigation energy), is a systemic conduction selective herbicide, the mechanism of action of synthetic hormones, is not easy to produce resistance, complete control, not easy to relapse, is the world's famous control of trees, shrubs, vines and Agents of malignant broadleaf weeds. This ingredient is absorbed by the leaves and roots of the plant, and is transmitted to the whole plant in the plant, causing deformity of the roots, stems, and leaves, exhaustion of stored substances, embolization or rupture of vascular bundles, and gradual death of the plant. Strong selectivity, highly safe for grass crops. It has special effects on a variety of vicious and difficult-to-control weeds such as chamaejasba, Oxytro...

AI Technical Summary

Problems solved by technology

Triclopyr (triclopyr), as a chloropyridine herbicide, has developed multiple synthetic routes at home and abroad: the original route will produce a large amount of waste water during condensation, and the highly toxic chloroacetic acid is used at the same time. Insufficient esterification leads to low yield. In the final condensation reaction, an isomer is produced which affects product quality. It is difficult to prepare high-quality products with a content of more than 98%.