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Experiment device for detecting activity of antineoplastic antibacterial peptide

A technology of activity detection and experimental device, which is applied in measurement devices, material inspection products, and microorganism determination/inspection, etc., can solve problems such as unsatisfactory experimental efficiency, and achieve the effect of convenient operation, high experimental efficiency and uniform mixing.

Active Publication Date: 2019-09-10
QINGDAO UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, when the activity of antitumor antimicrobial peptides is tested, a certain amount of antimicrobial peptide solution needs to be mixed with tumor cells, and then the tumor cells are measured to obtain antimicrobial peptides The degree of activity of the experiment requires multiple experiments for comparison, and the efficiency of the experiment is not ideal.

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  • Experiment device for detecting activity of antineoplastic antibacterial peptide
  • Experiment device for detecting activity of antineoplastic antibacterial peptide
  • Experiment device for detecting activity of antineoplastic antibacterial peptide

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Embodiment Construction

[0027] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0028] according to figure 1 , figure 2 , image 3 , Figure 5 , Figure 6 and Figure 7 The shown experimental device for antitumor activity detection of antimicrobial peptides includes a housing 1, a first reaction chamber 2 is provided inside the housing 1, and a second reaction chamber 3 is provided at the bottom of the first reaction chamber 2. The bottom of the second reaction chamber 3 is provided with a third reaction chamber 4, the top of the ho...

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Abstract

The invention discloses an experiment device for detecting activity of an antineoplastic antibacterial peptide, and particularly relates to the field of detection of activity of antibacterial peptides. The experiment device comprises a shell, a first reaction chamber is formed in the shell, a second reaction chamber is formed in the bottom of the first reaction chamber, and a third reaction chamber is formed in the bottom of the second reaction chamber; a tumor cell tank is arranged at the top of the shell, an alkaline reagent tank is formed in one side of the tumor cell tank, and feeding ports are formed in the tops of the tumor cell tank and the alkaline reagent tank; total pipes are arranged on one sides of the tumor cell tank and the alkaline reagent tank, first switch valves are arranged on the total pipes, three branch pipes are arranged at the bottom of each first switch valve, and second switch valves are arranged on the branch pipes. According to the experiment device, a tumorcell solution and an alkaline reagent are subjected to metrological control separately through transparent metering pipes and drained into mixing boxes at the same time for activity detection, imagesare displayed on a display screen at the same time and contrasted, and the experiment efficiency of the whole experiment device is higher.

Description

technical field [0001] The invention relates to the technical field of antibacterial peptide activity detection, and more specifically, the invention relates to an experimental device for antitumor antimicrobial peptide activity detection. Background technique [0002] Antimicrobial peptide refers to a class of basic polypeptide substances with antibacterial activity induced by insects, with a molecular weight of about 2000-7000 and composed of 20-60 amino acid residues. Most of these active peptides have the characteristics of strong alkalinity, thermal stability and broad-spectrum antibacterial properties. [0003] With the in-depth development of people's research work, it has been found that some antibacterial peptides have a strong killing effect on some fungi, protozoa, viruses, and cancer cells. Therefore, many scholars tend to name such active peptides as peptides. antibiotic. [0004] At present, when testing the activity of antitumor antimicrobial peptides, it is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/02G01N33/48
CPCG01N33/5011G01N33/48Y02A50/30
Inventor 石媛嫄白靖琨吴岁寒
Owner QINGDAO UNIV