Application of artificially synthesized antibacterial peptides in preparation of antibacterial, anti-inflammation and acne-removing cosmetics or external medicine preparations as well as antibacterial, anti-inflammation and acne-removing composition

A technology for artificial synthesis and external use of drugs, which can be used in drug combinations, cosmetics, antibacterial drugs, etc., and can solve the problems of low market application, high production costs, and complex processes.

Pending Publication Date: 2019-09-27
浙江星杭泰乐生物医药有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The invention patent with the application number CN102824282A discloses an antibacterial peptide skin care cosmetic. The patented product has the advantages of high stability, strong permeability, antibacterial factor and good skin care function. However, the product has no effect on the prevention and treatment of acne. Mention; the invention patent with the application publication number CN105411873A discloses a kind of anti-inflammatory and acne-removing agent in cosme

Method used

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  • Application of artificially synthesized antibacterial peptides in preparation of antibacterial, anti-inflammation and acne-removing cosmetics or external medicine preparations as well as antibacterial, anti-inflammation and acne-removing composition
  • Application of artificially synthesized antibacterial peptides in preparation of antibacterial, anti-inflammation and acne-removing cosmetics or external medicine preparations as well as antibacterial, anti-inflammation and acne-removing composition
  • Application of artificially synthesized antibacterial peptides in preparation of antibacterial, anti-inflammation and acne-removing cosmetics or external medicine preparations as well as antibacterial, anti-inflammation and acne-removing composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] See Table 1 for the proportioning of an antibacterial, anti-inflammatory, anti-acne composition containing antimicrobial peptides provided in this implementation.

[0095] The formula of the composition of table 1 embodiment 1

[0096]

[0097]

[0098] The preparation method of the above-mentioned anti-inflammatory and acne-removing composition containing antimicrobial peptides provided in this embodiment comprises the following steps:

[0099] S1 Mix the raw materials contained in phase A and stir at 80-90°C for 15-20 minutes to mix them evenly to form phase A;

[0100] S2 After the mixture of phase A is cooled to 50-55°C, add the raw materials contained in phase B to phase A, and stir for 30 minutes. After mixing evenly, the composition is obtained.

[0101] The antimicrobial peptide composition of the present invention still maintains high chemical and biological stability of the antimicrobial peptide after being stored at 1-6° C. for 24 months.

Embodiment 2

[0103] The ratio of an antibacterial, anti-inflammatory, and acne-removing composition containing antimicrobial peptides provided in this implementation is shown in Table 2. The preparation method is the same as that in Example 1, except that the ratio of raw materials is different.

[0104] The formula of the composition of table 2 embodiment 2

[0105]

Embodiment 3

[0107] The ratio of an antibacterial, anti-inflammatory, and anti-acne composition containing antimicrobial peptides provided in this implementation is shown in Table 3. The preparation method is the same as that in Example 1, except that the ratio of raw materials is different.

[0108] The formula of the composition of table 3 embodiment 3

[0109]

[0110]

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Abstract

The invention discloses an application of artificially synthesized antibacterial peptides in preparation of antibacterial, anti-inflammation and acne-removing cosmetics or external medicine preparations as well as antibacterial, anti-inflammation and acne-removing composition containing the antibacterial peptides. The antibacterial, anti-inflammation and acne-removing composition comprises 0.001-10 parts of antibacterial peptides, 0.001-10 parts of an antioxidant, 5-20 parts of a moisturizer, 0.1-5 parts of a penetrant, 70-95 parts of a carrier and a hydrotrote, 1-10 parts of a thickening agent or a gelling agent and 0.5-12 parts of a pH buffering agent. The composition is added to cosmetics or external medicine preparations with antibacterial peptides as antibacterial agents, has the functions of regulating sebum secretion of skin, diminishing inflammation and relieving swelling, particularly has good inhabitation and killing effects on propionibacterium acnes causing acne, can effectively prevent and remove acne and pimples and makes skin full of vitality and vigor. The antibacterial peptides have wide application range, can be well compatible with most cosmetic materials or external medicine preparation materials and are simple and convenient to add.

Description

technical field [0001] The present invention relates to the field of anti-inflammatory and anti-acne products, more specifically, it relates to the application of a class of artificially synthesized antibacterial peptides in the preparation of cosmetics or external pharmaceutical preparations for antibacterial, anti-inflammatory and anti-acne products, and antibacterial, anti-inflammatory and anti-acne products containing the antibacterial peptides. Composition for acne. Background technique [0002] Acne, also known as "acne", "pimples" or "pimples", is a common chronic hair follicle and sebaceous gland inflammatory skin disease caused by multiple factors. parts. The etiology is not only related to factors such as endocrine, immunity, excessive sebaceous gland secretion and hyperkeratosis of hair follicles, but also closely related to the mixed infection of Propionibacterium acnes, Staphylococcus epidermidis, Staphylococcus aureus and other bacteria. Among them, Propionib...

Claims

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Application Information

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IPC IPC(8): A61K38/07A61P31/04A61P17/10A61K8/64A61Q19/00
CPCA61K38/07A61P31/04A61P17/10A61K8/64A61Q19/00
Inventor 胡庆堂范伟民程浩楼威洋钟冠盛郑俊
Owner 浙江星杭泰乐生物医药有限公司
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