A dry eye moisturizing spray and preparation method thereof

A technology for moisturizing spray and dry eye, which is applied in the field of dry eye moisturizing spray and its preparation, which can solve the problems of poor compliance of patients and achieve the effects of accelerated recovery, gentle and safe administration, and scientific prescription proportioning

Active Publication Date: 2021-11-09
WENZHOU MEDICAL UNIV
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Patent CN1456167A provides an artificial tear containing phospholipids, and patent CN1651090A provides an ocular drug delivery system containing trehalose and hyaluronic acid. The above treatment strategies are all effective by dripping into the patient's eyes, but in actual operation many The patient has obvious discomfort in the process of adding eye drops and artificial tears, and the patient's compliance is poor
In addition, many ocular medications currently available for dry eye lack the effectiveness of simultaneously keeping the eye moist while treating the ocular damage caused by dry eye

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A dry eye moisturizing spray and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] The invention relates to a preparation method of dry eye moisturizing spray, which comprises hyaluronic acid, aloe extract, allantoin, sodium chloride and phosphate buffer saline.

[0046] Prepare 100g of this spray, take each component by weight as follows:

[0047] Hyaluronic acid: 0.01g

[0048] Aloe Vera Extract: 0.2g

[0049] Allantoin: 0.25g

[0050] Sodium chloride: 0.9g

[0051] Add pure water to 100g,

[0052] And use an appropriate amount of phosphate buffer to adjust the pH to 7.0~7.5.

[0053] Wherein the preparation process is as follows:

[0054] A. Pre-sterilize all containers used to prepare the moisturizing spray,

[0055] B. The above raw materials were weighed and mixed,

[0056] C. Add ultrapure water to a total mass of 100g, use phosphate buffer to adjust the pH to 7.0~7.5, and fully stir to dissolve at normal temperature and pressure.

Embodiment 2

[0058] A moisturizing spray for dry eyes, which comprises dextran 70, dipotassium glycyrrhizinate, allantoin, sodium chloride and phosphate buffer.

[0059] Prepare 100g of this spray, take each component by weight as follows:

[0060] Dextran 70: 0.03g

[0061] Dipotassium glycyrrhizinate: 0.3g

[0062] Allantoin: 0.2g

[0063] Sodium chloride: 0.7 parts

[0064] Add pure water to 100g, and use an appropriate amount of phosphate buffer to adjust the pH to 7.0~7.5.

[0065] Wherein the preparation process is as follows:

[0066] A. Pre-sterilize all containers used to prepare the moisturizing spray,

[0067] B. The above raw materials were weighed and mixed,

[0068] C. Add ultrapure water to a total mass of 100g, use phosphate buffer to adjust the pH to 7.0~7.5, and fully stir to dissolve at normal temperature and pressure.

Embodiment 3

[0070] A moisturizing spray for dry eyes, which comprises hyaluronic acid, dipotassium glycyrrhizinate, allantoin, sodium chloride, potassium chloride, calcium chloride and phosphate buffer.

[0071] Prepare 100g of this spray, take each component by weight as follows:

[0072] Hyaluronic acid: 0.08g

[0073] Dipotassium glycyrrhizinate: 0.1g

[0074] Allantoin: 0.3g

[0075] Sodium chloride: 0.6g

[0076] Potassium chloride: 0.02g

[0077] Calcium chloride: 0.03g

[0078] Add pure water to 100g, and use an appropriate amount of phosphate buffer to adjust the pH to 7.0~7.5.

[0079] Wherein the preparation process is as follows:

[0080] A. Pre-sterilize all containers used to prepare the moisturizing spray,

[0081] B. The above raw materials were weighed and mixed,

[0082] C. Add ultrapure water to a total mass of 100g, use phosphate buffer to adjust the pH to 7.0~7.5, and fully stir to dissolve at normal temperature and pressure.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention provides a dry eye moisturizing spray, which mainly includes moisturizing ingredients, inflammation inhibitors, ulcer repair ingredients, osmotic regulators and pH buffers, and every 100 parts by weight of the moisturizing spray includes the following parts by weight: Components: Hydrating and moisturizing ingredients: 0.01-0.1 parts; Inflammation inhibitors: 0.1-0.3 parts; Ulcer repairing ingredients: 0.15-0.3 parts; Osmotic regulator: 0.6-0.9 parts; The balance is ultra-pure water, and use a pH buffer to adjust the pH to 7.0-7.5. The invention also provides a preparation method of the moisturizing spray. The moisturizing spray of the present invention is specially used for alleviating and treating symptoms related to dry eye syndrome. It produces micron-sized atomized droplets to warm and moisten the eyeball through a special atomizing moisturizing device. Dry symptoms, safe and non-toxic ingredients, low irritation, and high user compliance.

Description

technical field [0001] The invention relates to the field of eye care, in particular to a dry eye moisturizing spray and a preparation method thereof. Background technique [0002] Dry eye syndrome is a general term for a variety of diseases caused by a variety of reasons for the decrease in the stability of the tear film, accompanied by ocular discomfort and (or) ocular surface tissue lesions. The main symptoms of dry eye syndrome include dry eyes and fatigue, strong foreign body sensation in the eyes, burning sensation, fear of wind, photophobia, sensitivity to external stimuli, etc.; more severe cases will have red and swollen eyes, hyperemia, keratinization, corneal epithelial rupture, etc. There are filaments attached to the skin, and this kind of damage can cause keratoconjunctival lesions over time and affect vision. [0003] In general, dry eye treatment strategies include: [0004] 1. Eliminate the triggers: Avoid using computers for long periods of time, and avoi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/886A61K36/896A61K9/12A61K47/02A61P27/02A61K31/4166A61K31/704A61K31/721A61K31/728A61K33/14
CPCA61K9/0048A61K9/12A61K31/4166A61K31/704A61K31/721A61K31/728A61K33/14A61K36/886A61K36/896A61K47/02A61P27/02A61K2300/00
Inventor 周铁丽方人驰曹建明陈涛张秀彩
Owner WENZHOU MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap