Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of 2,4-diaminophenoxyethanol hydrochloride

A technology of diaminophenoxyethanol hydrochloride and dinitrobenzene, which is applied in two fields, can solve the problems of high price, and achieve the effects of low production cost, simple raw materials, and convenient industrial production

Inactive Publication Date: 2019-11-15
YIXING XINYU CHEM
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] 2,4-diaminophenoxyethanol hydrochloride, currently the main foreign producers of this product are James Robinson Company in India and JOS.H.LOEENSTEIN Company in the United States, and most of the domestic market still needs to be imported, which is expensive

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0012] In order to make the technical means, creative features, goals and effects achieved by the present invention easy to understand, the present invention will be further described below in conjunction with specific embodiments.

[0013] A kind of preparation method of 2,4-diaminophenoxyethanol hydrochloride, comprises the following steps:

[0014] (1) Using 1,5-dichloro-2,4-dinitrobenzene and 1,2-propanediol as raw materials, using dichloromethane as a solvent, reacting at a temperature of 50-60°C for 20 hours to prepare The intermediate product was obtained; the reaction molar ratio of 1,5-dichloro-2,4-dinitrobenzene and 1,2-propanediol was 1:8.

[0015] (2) Use the intermediate product obtained in step (1) as a raw material, use dichloromethane as a solvent, add a reducing agent and a catalyst, react at a temperature of 50-60°C for 4-5 hours, add hydrochloric acid and water , then concentrate the water and dichloromethane to dryness under reduced pressure, add ethanol, ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a preparation method of 2,4-diaminophenoxyethanol hydrochloride. The preparation method comprises the following steps: taking 1,5-dichloro-2,4-dinitrobenzene and 1,2-propylene glycol as raw materials, and taking a protic solvent or a polar aprotic solvent as a solvent to carry out reacting for 20 hours at a temperature of 50-60 DEG C to prepare an intermediate product; taking the intermediate product as a raw material, taking dichloromethane as a solvent, adding a reducing agent and a catalyst, carrying out reacting for 4-5 hours at a temperature of 50-60 DEG C, adding hydrochloric acid and water, then carrying out vacuum concentration drying to remove the water and dichloromethane, adding ethanol, carrying out reflux for 4-5 hours, and finally adding hydrochloric acid for acidification to obtain the 2,4-diaminophenoxyethanol hydrochloride. According to the preparation method, the product is synthesized in two steps, the raw materials are simple and easily available, the synthesis process is simple, amplification production is facilitated, production cost is low, industrial production is facilitated, and the preparation method has a great market potential.

Description

technical field [0001] The invention belongs to the technical field of organic chemical synthesis, and in particular relates to a preparation method of 2,4-diaminophenoxyethanol hydrochloride. Background technique [0002] 2,4-Diaminophenoxyethanol hydrochloride is mainly produced abroad by JAMES ROBINSON Company in India and JOS.H.LOEENSTEIN Company in the United States, and most of the domestic market still needs to be imported, which is expensive. Due to the great demand for 2,4-diaminophenoxyethanol hydrochloride in the market, it is urgent to develop a preparation method with reasonable cost and suitable for industrial production. Contents of the invention [0003] In order to solve the above technical problems, the present invention provides a method for preparing 2,4-diaminophenoxyethanol hydrochloride. [0004] In order to achieve the above object, the concrete technical scheme that the present invention adopts is as follows: [0005] A kind of preparation method...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07C213/02C07C213/08C07C217/84C07C201/12C07C205/37
CPCC07C201/12C07C213/02C07C213/08C07C205/37C07C217/84
Inventor 袁顺福范洪振袁郡范琳许薇
Owner YIXING XINYU CHEM
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com