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Novel turmeric rhizome composite solid preparation and preparation method thereof

A technology of solid preparation and turmeric is applied in the fields of nutrition and health care products, food and medicine to achieve the effects of reducing production costs, making the preparation process green and environmental protection, and improving biological activity.

Pending Publication Date: 2019-11-19
广州市康伦生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, polymer materials are mainly used to improve the water solubility and stability of curcumin at home and abroad: patent CN108815123A uses polyvinylpyrrolidone, poloxamer 188, etc. as auxiliary materials to prepare curcumin solid dispersion; patent CN107496359A uses Pluronic F127, etc. Curcumin liposome, the patent CN106943604A adopts cyclodextrin polymer to prepare water-soluble curcumin supramolecular inclusion complex, and there are no related documents and patent reports about using turmeric's own soluble fiber to absorb and disperse curcumin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] (1) Take turmeric medicinal material, pulverize it and pass through a 24-mesh sieve to obtain turmeric medicinal powder;

[0033] (2) Take turmeric powder, add deionized water according to the material-to-liquid ratio of 1:8, infiltrate for 20 minutes, heat and distill at 100°C for 6 hours, and collect through separation and extraction to obtain turmeric volatile oil;

[0034] (3) Add 65% ethanol water to the turmeric medicine powder residue extracted in step (2) according to the material-to-liquid ratio of 1:10, heat and extract at 65°C for 2 hours, extract twice, filter through 100 mesh, and combine the filtrates to obtain curcumin ethanol solution , add 5% polyglycerol monooleate, homogeneously emulsify at 3000rpm, obtain curcumin emulsified solution;

[0035] (4) Add deionized water to the turmeric powder residue extracted in step (3) according to the ratio of material to liquid 1:10, adjust the pH to 5.0 with citric acid, heat at 100°C for 36 h, filter through 100 ...

Embodiment 2

[0040] (1) Take turmeric medicinal material, pulverize it and pass through a 24-mesh sieve to obtain turmeric medicinal powder, which is set aside;

[0041] (2) Take turmeric powder, add deionized water according to the material-to-liquid ratio of 1:10, soak for 25 minutes, heat and distill at 100°C for 6 hours, and collect through separation and extraction to obtain turmeric volatile oil;

[0042](3) Add 80% ethanol water to the turmeric powder residue extracted in step (2) according to the ratio of material to liquid 1:8, heat and extract at 65°C for 3 hours, extract twice, filter through 100 mesh, and combine the filtrates to obtain curcumin ethanol solution , add 2% polyglycerol monooleate and 3% Tween-20, homogeneously emulsify at 3000 rpm, obtain curcumin emulsified solution;

[0043] (4) Add deionized water to the turmeric powder residue extracted in step (3) according to the ratio of material to liquid 1:5, adjust the pH to 5.5 with citric acid, heat at 100°C for 12 ho...

Embodiment 3

[0048] (1) Take turmeric medicinal material, pulverize it and pass through a 24-mesh sieve to obtain turmeric medicinal powder, which is set aside;

[0049] (2) Take turmeric powder, add deionized water according to the material-to-liquid ratio of 1:6, soak for 20 minutes, heat and distill and extract at 100°C for 4 hours, and collect through separation and extraction to obtain turmeric volatile oil;

[0050] (3) Add 70% ethanol water to the turmeric medicine powder residue extracted in step (2) according to the ratio of material to liquid 1:8, heat and extract at 60°C for 4 hours, extract twice, filter through 100 mesh, and combine the filtrates to obtain curcumin ethanol solution , add 4% polyglycerol monooleate and 1% soybean protein isolate, and emulsify homogeneously at 3000 rpm to obtain curcumin emulsified solution;

[0051] (4) Add deionized water to the turmeric powder residue extracted in step (3) according to the ratio of solid to liquid 1:7, adjust the pH to 6.5 wi...

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Abstract

The invention relates to a turmeric rhizome composite solid preparation which is prepared by taking medicinal and edible resource of turmeric rhizome extracts including curcumin, turmeric volatile oiland turmeric soluble fibers as raw materials. The turmeric rhizome composite solid preparation is composed of the following components in percentage by weight: 0.5%-30% of the curcumin, 0.5%-50% of the turmeric soluble fibers, 1%-10% of the turmeric volatile oil, 0.5%-10% of a food emulsifier and the balance of a filling agent. According to the technology disclosed by the invention, effective components of the curcumin, the turmeric volatile oil and the turmeric soluble fibers of turmeric rhizomes are fully extracted and applied, the turmeric rhizome composite solid preparation is obtained through emulsion homogenizing emulsification, concentration and drying processes, the water solubility and bioavailability of the curcumin are effectively improved, and the turmeric rhizome composite solid preparation can be used as a functional raw material to be applied to the fields of foods, nutritional health-care products, medicines and the like.

Description

technical field [0001] The invention belongs to the technical fields of food, nutraceuticals, medicine and the like. The invention relates to a turmeric composite solid preparation and a preparation method thereof, in particular to a turmeric composite solid preparation prepared from curcumin, turmeric soluble fiber, turmeric volatile oil, food emulsifier and filler as raw and auxiliary materials and a preparation method thereof . Background technique [0002] Turmeric is derived from the dried rhizome of turmeric, a plant of the family Zingiberaceae. It is pungent, bitter, and warm in nature and belongs to the spleen and liver meridians. The effect of turmeric is to break blood and promote qi, stimulate menstruation and relieve pain. It is used for tingling pain in the chest and hypochondrium, chest pain, dysmenorrhea, amenorrhea, lump in the abdomen, rheumatism, shoulder and arm pain, tumbling and swelling. The active ingredients of turmeric mainly include curcumin, vola...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K31/12A61P29/00A61P39/06A23L33/105A23L33/115A23P10/47
CPCA61K36/9066A61K31/12A61P29/00A61P39/06A23L33/105A23L33/115A23P10/47A61K2236/331A61K2236/39A23V2002/00A61K2300/00A23V2200/30A23V2250/2112A23V2300/14
Inventor 杜志云林丽马诗经李志威朱林静韩萍郑希
Owner 广州市康伦生物技术有限公司
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