Blood collection separation tube and separation method

Abstract

The invention discloses a blood collection separation tube and a separation method. The blood collection separation tube comprises a test tube and a rubber plug arranged at the top of the test tube, aconcave cavity is disposed at the bottom surface center of the rubber plug, a positioning annular plate is arranged at the bottom surface of the rubber plug, the inner circle of the positioning annular plate is located right below the concave cavity, and the diameter of the inner circle is smaller than that of the concave cavity. The blood collection separation tube also includes a physical separator arranged below the rubber plug, the upper end of the physical separator has a protruding part, which is clamped between the concave cavity and the positioning annular plate, the inner diameter ofthe test tube has a big end up, the conicity of the physical separator is identical to that of the test tube, and the physical separator is a solid elastic object. According to the blood collection separation tube and the separation method provided by the invention, a physical mode is employed for isolation of blood cells and serum / blood plasma after centrifugation, extra impurities in serum / blood plasma can be avoided after centrifugation, sampling needle blocking cannot be caused, and the detection result cannot be affected either.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a blood collection separation tube and a separation method. Background technique [0002] In the medical field, medical personnel collect venous blood samples to obtain human physiological and pathological information for correct diagnosis of diseases, which is widely used in clinical practice. Blood collection tubes usually contain additives (anticoagulants or coagulants), which can be separated by centrifugation due to the density gradient between blood cells and serum / plasma. Then take serum / plasma and use biochemical or immunological methods for disease diagnosis. In order to prevent the exchange of substances between blood cells and serum / plasma, and to ensure that the biochemical properties and chemical processes of serum / plasma do not change for a long time, separation gels are often used in clinical practice to isolate blood cells from serum / plasma, but the curre...

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Problems solved by technology

[0003] The technical problem to be solved by the present invention is that separation gel is often used in clinical practice to block blood cells and serum / plasma, but the separation gel is a high molecular polymer, and small particles and agglomerates are often precipitated and floated in serum / plasma after centrifugation. In the process, the fibrin filaments (or clusters) after centrifugation are also floating in the serum / plasma; causing the sampling needle to be blocked during sampling. Isolation from serum / plasma can avoid extra impurities in serum / plasma after centrifugation, will not cause clogging of the sampling needle and will not affect the test results, and secondly, it can solve the uneven quality of serum separation gels on the market or be affected by storage temperature , often have the defect that the centrifugation process of the serum separation gel cannot be completely reversed or the blood cells cannot be completely blocked from the serum / plasma

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