Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Elastic degradable tracheal stent and construction method thereof

A technique for tracheal stents and construction methods, applied in stents, coatings, medical science, etc., to achieve good tissue infiltration, good elasticity, and good pore connectivity

Active Publication Date: 2019-12-17
FOURTH MILITARY MEDICAL UNIVERSITY
View PDF4 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, it has not been successfully reported that the above three conditions can be satisfied at the same time.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Elastic degradable tracheal stent and construction method thereof
  • Elastic degradable tracheal stent and construction method thereof
  • Elastic degradable tracheal stent and construction method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0043] The present invention will be described in detail below in combination with specific embodiments.

[0044] The invention relates to an elastic degradable tracheal stent, the stent is a three-layer elastic tracheal composite structure, which sequentially includes a PGS tube core, a C-shaped PCL ring and a PCL sheath arranged in parallel to form a PGS tube core-C Type PCL ring-PCL sheath has elastic degradable tracheal stent material.

[0045] The PGS core is a tubular structure made of polyglycerol sebacate (PGS) material; the C-shaped PCL ring is a C-shaped structure made of polycaprolactone (PCL); the PCL sheath The layer is a polycaprolactone sheath prepared by electrospinning. The C-type PCL ring is used as the middle supporting ring layer, including at least two rings, which are equal in size and arranged in parallel axially. The inner diameter of the stent is 4-9 mm, and the outer diameter is 6-11 mm; the width of the C-type PCL ring is 2-3 mm, and the adjacent d...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
The inside diameter ofaaaaaaaaaa
Outer diameteraaaaaaaaaa
Login to View More

Abstract

The invention relates to an elastic degradable tracheal stent and a construction method thereof. The stent is of a three-layer elastic tracheal shape composite structure, and successively includes a PGS tube core, C-type PCL rings arranged in parallel and a PCL sheath layer from inside to outside; the PGS tube core is of a tubular structure made of a poly(glycerol-sebacate) material; the C-type PCL rings are of C-type structures made of polycaprolactone, and the PCL sheath layer is a polycaprolactone sheath layer prepared by electrospinning. According to the elastic degradable tracheal stent and the construction method thereof, by constructing a three-layer elastic tracheal shape composite scaffold material with the PGS tube core-C-type PCL rings-PCL sheath layer, a tracheal scaffold material with good elasticity, good pore connectivity, good support and timely degradation is obtained, the tracheal scaffold material is superior to other tissue engineering materials in the past, the scaffold material can realize the advantages of rapid vascularization, good tissue infiltration, good flexibility and the like, and the scaffold material paves the way for follow-up application in clinical researches.

Description

technical field [0001] The invention relates to the technical field of biomedical devices, in particular to an elastic degradable tracheal stent and a construction method thereof. Background technique [0002] Tracheal tumors, tracheal trauma, or congenital tracheal deformities often lead to tracheal stenosis and even seriously threaten the lives of patients. Clinically, the incidence of tracheal malformation is high in children with congenital heart disease. According to literature reports, tracheal malformation accounts for about 12.9% of children with congenital heart disease. In my country, the incidence of congenital heart disease accounts for 0.7%-0.8%, and it is increasing by about 150,000 children every year. Among them, many children with congenital heart disease are complicated with tracheal deformities every year. Tracheal stenosis is the most common form of tracheal malformation, and compression and softening of the trachea by cardiovascular malformations is on...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61F2/82D01D5/00B29C33/38B29C64/153B33Y10/00
CPCA61F2/82D01D5/0007D01D5/003D01D5/0084B29C64/153B29C33/3842B33Y10/00A61F2240/002
Inventor 吴炜加三三张心驰张思倩
Owner FOURTH MILITARY MEDICAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com