Unlock instant, AI-driven research and patent intelligence for your innovation.

Antimicrobial compounds and nanostructures

A compound and composition technology, applied in the field of treatment of diseases, can solve the problems of long dehydration time, ineffectiveness and the like

Active Publication Date: 2020-01-31
THE BOEING CO
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In addition, the hydrophobic binding of existing antimicrobial materials requires a long dehydration time before being effective, so that a large amount of microbial transmission occurs during the dehydration process, so that the antimicrobial activity is ineffective against strong microorganisms such as Escherichia coli (E.coli)

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Antimicrobial compounds and nanostructures
  • Antimicrobial compounds and nanostructures
  • Antimicrobial compounds and nanostructures

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0214] experiment:

[0215] Measurement

[0216] Nuclear Magnetic Resonance (NMR). All NMR spectra were performed using an external lock (CDCl 3 or DMSO-d 6 ) and referenced to residual non-deuterated solvent (CHCl 3 or DMSO) were recorded on a Bruker DRX 400 or 500 MHz spectrometer.

[0217] Size Exclusion Chromatography (SEC) and Triple Detection-Size Exclusion Chromatography (TD-SEC). Molecular weight distribution analysis of polymers was determined using a Polymer Laboratories GPC50 Plus equipped with a differential refractive index detector. The absolute molecular weight of the polymers was determined using a Polymer Laboratories GPC50Plus equipped with a dual angle laser light scattering detector, viscometer and differential refractive index detector. High performance liquid chromatography (HPLC) grade N,N-dimethylacetamide (DMAc, containing 0.03% by weight LiCl) was used as eluent at a flow rate of 1.0 mL / min. Separation was performed using two PLGel Mixed B ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present disclosure provides compounds and nanostructures having one or more quaternary ammonium salts, compositions including the compounds and nanostructures, and methods useful for treating conditions using the compounds, nanostructures, and compositions. In at least one aspect, a compound is represented by formula (I): or a pharmaceutically acceptable salt thereof, wherein: Q is fluoro, chloro, bromo, or iodo; each of s, b, and n is independently an integer from about 10 to about 100; and each of v, j, p, z, q, x and m is independently an integer from 1 to about 20.

Description

[0001] Cross References to Related Applications [0002] This application is a PCT application claiming priority to co-pending U.S. Nonprovisional Patent Application No. 15 / 838,751, filed December 12, 2017, which claims co- Benefit of pending U.S. Provisional Patent Application Serial No. 62 / 521,040. The entire contents of the above-mentioned related patent applications are hereby incorporated by reference. technical field [0003] The present invention provides compounds and nanostructures having one or more quaternary ammonium salts, compositions comprising the compounds and nanostructures, and methods of using the compounds, nanostructures and compositions to treat disorders. Background technique [0004] Preventing the spread of disease on airplanes usually focuses on improvements to air conditioning / filtration systems. Recent research suggests that one way to further improve disease prevention on board aircraft and spacecraft could include surface contamination treatm...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/787A61K31/795C08F120/34C08F120/56
CPCA01N47/02C08F293/005C08F212/08C08F120/34A61K31/795C08F2438/03C07D207/416C08F299/00Y02A50/30A61K2300/00C08F220/54A61K31/4188A61K31/4402A61K31/4015
Inventor M·蒙蒂罗J·W·阿姆斯特朗
Owner THE BOEING CO