Multiple-nuclide gamma imaging system and method

A nuclide and imaging technology, applied in the field of multi-nuclide gamma imaging systems, can solve the problems of difficulty in accurately delineating the scope of brain tumor tumor tissue infiltration, limited accuracy, and single information, and achieves wide practical value, The effect of improving the system signal-to-noise ratio and reducing the demand

CN110772274AInactive Publication Date: 2020-02-11NANCHANG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2020-02-11
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention discloses a multiple-nuclide gamma imaging system and method and belongs to the field of medical imaging. The multiple-nuclide gamma imaging system comprises a multiple-nuclide tracer injection module, a multi-nuclide scintillation crystal detector module, a configurable circuit module and an image reconstruction and imaging module. The multiple-nuclide gamma imaging method comprises the following steps: S1, starting the imaging system, setting acquisition time of the imaging system, and injecting 11C, 13N, 15O and 18F labeled compounds into an imaging object; S2, obtaining a decay event emission gamma pulse data set by positioning a gamma detector; S3, outputting an electrical signal (scintillation pulse) by a silicon photomultiplier; S4, conducting time discrimination, energy discrimination, data acquisition and coincidence processing by a detector; and S5, displaying images in a tomographic manner by a computer. The disclosed multiple-nuclide gamma imaging system and method can obtain more comprehensive data than the prior art, comprehensively analyze multi-molecule events and related influences, reduce requirements on the total gamma photon counting, reduce irradiation risks on organisms and improve a signal-to-noise ratio of reconstructed images.
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Description

technical field

[0001] The invention relates to the field of medical imaging, in particular to a multi-nuclide gamma imaging system and method. Background technique

[0002] Gamma or gamma-ray (γ-ray) imaging technology and systems play an important role in the research of many aspects of life science or biomedicine (such as genetics, genetics, etc.), especially in precision medicine and targeted diagnosis and treatment. It is an important means or approach for understanding, diagnosing, treating diseases and developing new drugs. It not only promotes the development of molecular biology and molecular medicine, but also promotes the progress of molecular imaging technology. It uses radionuclide-labeled tracer molecules to participate in the physiological metabolic process of organisms, detects X-rays or gamma photons emitted by radionuclide outside the body and reconstructs the image to obtain the distribution of radionuclide, so as to use radioactive elements Tracing metho...

Examples

Embodiment Construction

[0028] The technical solutions of the present invention will be further described below in conjunction with the accompanying drawings and through specific implementation methods.

[0029] Such as Figure 1-Figure 4 As shown, according to one aspect of the present invention, a multi-nuclide gamma imaging system is provided in this embodiment, including a multi-nuclide tracer injection module 100, a multi-nuclide scintillation crystal detector module 200, which can Configuration circuit module 300, image reconstruction and imaging module 400, multi-nuclide tracer injection module 100 has a corresponding 11 C. 13 N. 15 O. 18 Four independently controllable channels of F gamma photon rays, the multi-nuclide scintillation crystal detector module 200 consists of corresponding 11 C. 13 N. 15 O. 18 F is made up of detectors of nuclides of four kinds of energies, which are fixed by a ring bracket, and an imaging object is placed in the center of the circle. The multi-nuclides tr...