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Preparation method of medical catheter with ultrasonic capability and product thereof

A medical catheter and capability technology, applied in the field of medical catheter preparation, can solve problems such as difficulty in precise positioning, delayed treatment timing, inability to precisely position, etc., and achieve the effects of low price, good ultrasound imaging, and obvious effects

Active Publication Date: 2020-02-18
BEIJING UNIV OF CHEM TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Medical catheters have become an indispensable tool in medical treatment. When medical catheters are inserted into the human body for operation, it is difficult for inexperienced doctors to achieve accurate positioning during intubation. At the same time, they cannot be accurately positioned many times during intubation. Causes great pain to the patient and sometimes delays the timing of treatment

Method used

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  • Preparation method of medical catheter with ultrasonic capability and product thereof
  • Preparation method of medical catheter with ultrasonic capability and product thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] (1) Accurately weigh 100 parts of polyether polyol (303), 25 parts of polyether polyol (390), 4.5 parts of triethanolamine, 1.0 part of deionized water, 1,1,1-trimethylol Mix 1.2 parts of propane, 1.8 parts of 1,4-butanediol and 2.2 parts of silicone oil, stir at a speed of 300r / min for 30s, and let stand to form a composite material (material A);

[0028] (2) Accurately weigh 167 parts of isocyanate prepolymer MDI, which is material B;

[0029] (3) Quickly pour material B into material A, and stir at 300r / min for 35s, then immediately pour the whitened material into the mold to foam freely, and take out the foam after about 6 minutes to obtain rigid polyurethane foam (RPUF ), sample cutting after normal temperature curing;

[0030] (4) Blending the cut sample in step (3) with TPU pellets, the ratio of TPU / RPUF is 100 / 0, and it is sent into a twin-screw extruder for extrusion, the screw speed is 100r / min, and the extrusion temperature The temperature is 195°C, and the...

Embodiment 2

[0037] (1) Accurately weigh 100 parts of polyether polyol (303), 40 parts of polyether polyol (390), 5.0 parts of triethanolamine, 0.5 part of deionized water, 1,1,1-trimethylol Mix 1.5 parts of propane, 2.5 parts of 1,4-butanediol and 2.0 parts of silicone oil, stir at a speed of 300r / min for 30s, and let stand to form a composite material (material A);

[0038] (2) Accurately weigh 165 parts of isocyanate prepolymer MDI, which is material B;

[0039] (3) Quickly pour material B into material A, and stir at 300r / min for 35s, then immediately pour the whitened material into the mold to foam freely, and take out the foam after about 6 minutes to obtain rigid polyurethane foam (RPUF ), sample cutting after normal temperature curing;

[0040] (4) Blending the cut sample in step (3) with TPU pellets, the ratio of TPU / RPUF is 90 / 10, and it is sent into a twin-screw extruder for extrusion, the screw speed is 100r / min, and the extrusion temperature The temperature is 190°C, and the...

Embodiment 3

[0046] (1) Accurately weigh 100 parts of polyether polyol (303), 30 parts of polyether polyol (390), 5.0 parts of triethanolamine, 1.0 part of deionized water, 1,1,1-trimethylol Mix 1.0 parts of propane, 2.0 parts of 1,4-butanediol and 2.0 parts of silicone oil, stir at a speed of 300r / min for 30s, and let stand to form a composite material (material A);

[0047] (2) Accurately weigh 168 parts of isocyanate prepolymer MDI, which is material B;

[0048] (3) Quickly pour material B into material A, and stir at 300r / min for 35s, then immediately pour the whitened material into the mold to foam freely, and take out the foam after about 6 minutes to obtain rigid polyurethane foam (RPUF ), sample cutting after normal temperature curing;

[0049] (4) Blending the cut sample in step (3) with TPU pellets, TPU / RPUF is 80 / 20, and sent into a twin-screw extruder for extrusion, the screw speed is 105r / min, and the extrusion temperature is 190 ℃, the wire sample was obtained after cooling...

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Abstract

The invention discloses a preparation method of a medical catheter with ultrasonic capability. The preparation method comprises the following steps that 1), polyether polyol, polyether polyol, triethanolamine, deionized water, 1,1,1-trimethylolpropane, 1,4-butanediol and silicone oil are mixed and stirred to form a material A; 2), isocyanate prepolymer MDI is taken as a material B; 3), the material B is quickly poured into the material A, after being stirred, the mixed material is poured into a mold to be freely foamed, foam is taken out so that a hard polyurethane foam RPUF can be prepared, and finally sample cutting is performed after aging at room temperature; and 4), the cut sample in step 3) is blended with thermoplastic polyurethane TPU pellets, wherein the ration of TPU / RPUF was 2.3-4, and extruding and cooling are performed so that a wire rod can be obtained. The medical catheter obtained by adopting the preparation method has good ultrasonic imaging effects, and can meet the application requirements of the medical industry compared with an existing medical catheter with mechanical properties.

Description

technical field [0001] The invention belongs to the field of biomedical materials, and relates to a preparation method of a medical catheter with ultrasonic capability and a product thereof. Background technique [0002] With the development of disciplines such as medicine, materials science, biology and chemistry, medical polymer materials have been widely used in the field of biomedicine. First of all, polymer materials have excellent mechanical properties and chemical stability, which are very suitable for medical use. Secondly, polymer materials have a wide range of sources and low prices, and are suitable for making disposable medical products, avoiding the problems of disinfection and cross-infection caused by the high price of traditional material products that have to be used many times. [0003] Polyurethane (PU) has been used in the production of medical catheter materials for a long time. It has stable chemical properties and has good biocompatibility such as low...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B29C48/05B29C48/40B29B9/06B29C45/00B29C45/78B29C44/02C08G18/79C08G18/66C08G18/48C08G18/32
CPCB29B9/06B29C44/02B29C45/00B29C45/78B29C48/05B29C48/40B29C2945/76531B29L2031/753C08G18/3206C08G18/3278C08G18/4804C08G18/6674C08G18/6677C08G18/6688C08G18/794
Inventor 徐福建王明丁小康丁雪佳
Owner BEIJING UNIV OF CHEM TECH