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Microfluidic temperature control system and nucleic acid analysis system

A temperature control system and nucleic acid analysis technology, applied in the field of microfluidics, can solve the problems of high thermal inertia, achieve the effects of reducing thermal inertia, rapid PCR amplification reaction, and reducing complexity

Active Publication Date: 2020-02-18
深圳市呈晖医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Based on this, it is necessary to provide a microfluidic temperature control system and nucleic acid analysis system for the high thermal inertia of the air and structural parts in the chamber of the centrifugal microfluidic chip.

Method used

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  • Microfluidic temperature control system and nucleic acid analysis system
  • Microfluidic temperature control system and nucleic acid analysis system
  • Microfluidic temperature control system and nucleic acid analysis system

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Embodiment Construction

[0020] In order to facilitate the understanding of the present application, the microfluidic temperature control system and the nucleic acid analysis system will be more fully described below with reference to the relevant drawings. The preferred embodiments of the microfluidic temperature control system and nucleic acid analysis system are given in the accompanying drawings. However, the microfluidic temperature control system and nucleic acid analysis system can be implemented in many different forms, and are not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the microfluidic temperature control system and nucleic acid analysis system more thorough and comprehensive.

[0021] It should be noted that when an element is referred to as being “fixed” to another element, it can be directly on the other element or there can also be an intervening element. When an element is referred to as being...

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Abstract

The present invention relates to a microfluidic temperature control system and a nucleic acid analysis system. The nucleic acid analysis system comprises an outer shell, a cover body, a temperature zone separation frame, an inner temperature control mechanism and an outer temperature control mechanism, and an accommodating cavity is formed in the cover body; the cover body covers the outer shell;the temperature zone separation frame is located in the accommodating cavity and connected with the outer shell; the inner temperature control mechanism is located in an inner temperature area and used for heating air temperature in the inner temperature area; and the outer temperature control mechanism comprises a first heating assembly and a second heating assembly, the first heating assembly and the second heating assembly are arranged in an outer temperature area at intervals. In the nucleic acid analysis system, a hot overshoot is applied to heating control and a cold overshoot is appliedto cooling control. Therefore, complexity of the nucleic acid analysis system is ingeniously reduced by reasonably utilizing layout of the structural areas, a problem of relatively high thermal inertia of air and structural parts in a cavity of a centrifugal micro-fluidic chip is solved, and time required by PCR analysis is further shortened.

Description

technical field [0001] The present application relates to the technical field of microfluidics, in particular to a microfluidic temperature control system and a nucleic acid analysis system. Background technique [0002] Polymerase chain reaction (PCR) is a method for amplifying a large number of specific DNA fragments. The reactants include templates, primers, polymerases and buffers, etc., and denaturation, annealing and extension are achieved by controlling the temperature of the reaction environment periodically. The cyclical cycle of the process. After each cycle, the specific DNA fragment is doubled, and after dozens of cycles, the amplified DNA sequence is easier to identify and detect. Polymerase chain reaction analysis technology is used in many fields such as biomedical research, environmental monitoring and protection, health and quarantine, judicial identification and disease diagnosis. [0003] Microfluidic technology can integrate the entire process of nuclei...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/38C12M1/02C12M1/00
CPCB01L7/5255B01L3/5027B01L2300/1894B01L2300/1838
Inventor 白晨
Owner 深圳市呈晖医疗科技有限公司
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