Intracavity tissue endoscope Raman spectroscopy detection device

A spectral detection and tissue technology, applied in the use of spectral diagnosis, oral mirror, diagnostic recording/measurement, etc., to achieve the effects of improving sensitivity and specificity, improving signal-to-noise ratio, and prolonging service life

Pending Publication Date: 2020-02-28
FUJIAN NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For nasopharyngeal electronic mirrors without biopsy holes, there is no biopsy channel, and the existing Raman probes passing through the biopsy holes cannot be used. Therefore, it is urgent to develop a device that is closely combined with electronic nasopharyngoscopes for spectral detection of nasopharyngeal tissue

Method used

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  • Intracavity tissue endoscope Raman spectroscopy detection device
  • Intracavity tissue endoscope Raman spectroscopy detection device
  • Intracavity tissue endoscope Raman spectroscopy detection device

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Embodiment Construction

[0021] see figure 1 , a kind of intracavitary tissue endoscopic Raman spectrum detection device 100, comprises a hand-held probe 1, Raman spectrometer 2, Raman excitation light source 3, white light source 4, fluorescence excitation light source 5, reflection / fluorescence spectrometer 6, detector ( not shown), an endoscope system 7; the hand-held probe 1 has a probe holder 11 and a fiber optic probe 12.

[0022] see again figure 1 and figure 2 , the probe holder 11 includes a handle 111 and a hollow probe conduit 112, the handle 111 is connected to one end of the probe conduit 112; the handle 111 includes a handle 111a and a finger hole 111b, the finger The hole 111b is provided at the lower end of the handle 111a. Both ends of the probe conduit 112 are open structures, one end of the probe conduit 112 corresponding to the handle 111 is the entrance end 1121, and the other end is the detection end 1122; the optical fiber probe 12 passes through the entrance end 1121, and ...

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Abstract

The invention provides an intracavity tissue endoscope Raman spectroscopy detection device which comprises a handheld probe. The handheld probe comprises a probe support and an optical fiber probe, the probe support comprises a handheld portion and a hollow probe catheter, the handheld portion is connected at one end of the probe catheter, openings are formed in the front end and the tail end of the probe catheter, one end of the probe catheter corresponding to the handheld portion serves as an inlet end, the other end of the probe catheter serves as a detecting end, and the optical fiber probe penetrates the inlet end and is fixed in the probe catheter. The device is applicable to a nasopharyngeal fiberscope, a biopsy channel of the nasopharyngeal fiberscope cannot be occupied, the biopsychannel and a channel for extracting intracavity mucus are reserved for a doctor, the handheld probe can be matched with an empty endoscope with a biopsy hole, and the handheld probe and an endoscopewithout a biopsy hole or nasopharyngeal hard endoscope can detect a nasopharyngeal tissue together. The device is applicable to a stomatoscope, a hysteroscope and the like, so that observation requirements of different human intracavity positions are met.

Description

【Technical field】 [0001] The invention specifically relates to a Raman spectrum detection device for intracavity tissue endoscopy. 【Background technique】 [0002] Nasopharyngeal carcinoma is one of the malignant tumors that occur in the head and neck, mainly in China's Fujian Province, Guangdong Province, Hong Kong, Southeast Asia and some countries in Asia. Because nasopharyngeal carcinoma has no obvious symptoms in the early stage and the nasopharynx is located deep in the head and neck, it is difficult to detect early nasopharyngeal carcinoma. By the time nasopharyngeal carcinoma is diagnosed, more than 70% of nasopharyngeal carcinoma patients are already in the advanced stage. The survival rate of early nasopharyngeal carcinoma is more than 90%, and the survival rate of advanced nasopharyngeal carcinoma is less than 30.3%. Therefore, the early diagnosis of nasopharyngeal carcinoma becomes the key to the treatment of nasopharyngeal carcinoma. Conventional diagnostic me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B1/233A61B1/24A61B1/267A61B1/303
CPCA61B1/233A61B1/24A61B1/267A61B1/303A61B5/0075A61B5/725
Inventor 陈荣林学亮黄伟陈冠楠冯尚源吴琼林慧晶黄祖芳
Owner FUJIAN NORMAL UNIV
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