Fluidized-bed spray granulation method for preparing probiotic microcapsule and product of fluidized-bed spray granulation method

A fluidized bed spray and microcapsule technology, applied in the direction of bacteria, lactobacillus, bifidobacteria, etc. used in food preparation, can solve the problems of harsh application conditions, less retention of probiotics, and limited storage environment. Achieving the effect of reducing moisture and water activity

Pending Publication Date: 2020-05-12
INNER MONGOLIA MENGNIU DAIRY IND (GRP) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the products related to probiotics are generally applied in the field of medicine, such as compressed tablets, capsules, powders, etc., generally need to be stored in low temperature refrigeration, and the storage environment is limited. Therefore, the application field is very limited
[0006] In addition, in the field of dairy products, prob

Method used

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  • Fluidized-bed spray granulation method for preparing probiotic microcapsule and product of fluidized-bed spray granulation method
  • Fluidized-bed spray granulation method for preparing probiotic microcapsule and product of fluidized-bed spray granulation method
  • Fluidized-bed spray granulation method for preparing probiotic microcapsule and product of fluidized-bed spray granulation method

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preparation example Construction

[0073] The invention relates to a preparation method of probiotic microcapsules, the probiotic microcapsules have one or more layers of embedding structure, including: bacterial core particles and optional at least one shell covering the bacterial core particles , wherein, the core particles include a core material and a first layer of wall material, the core material includes one or more probiotic powder or bacteria slime, and the core material is covered by the first layer of wall material , and the at least one shell covering the core particles includes one, two or more layers of wall materials, which are respectively the second layer of wall materials, the third layer of wall materials or more layers of wall materials, wherein , including the following steps:

[0074] (1) Preparation of single-layer microcapsules: Optionally mix and granulate bacteria powder or bacteria slime with binder, then uniformly mix with the first wall material by fluidized bed spray granulation me...

Embodiment 1

[0248] 1. Raw materials (based on 1000g dry microcapsules)

[0249] WPI: 550g, concentration 11%;

[0250] Bacteria powder 250g;

[0251] Curing agent solution: 0.5mol / L, pH-4.6

[0252] Palm oil: 200g

[0253] Starch: temperature 30°C, concentration 5%

[0254] 2. Preparation method

[0255] a. Mix whey protein with water and stir at 180rpm / min at 4°C for 16 hours;

[0256] b. heat-treat the whey protein solution at 78°C, 95rpm / min, and 45 minutes;

[0257] c. Cool immediately at 0°C; store at 4°C for 12 hours;

[0258] d. Mix 137g of sodium acetate, 100ml of glacial acetic acid and 6718g of water to make a curing agent solution, adjust the pH to 4.6, add 2.9g of Tween-20, mix well and set aside.

[0259] e. Fluidized bed granulation method: Put the probiotic powder into the fluidized bed, start the air intake to circulate the powder, and atomize the binder solution through the spray gun (the dosage and spray speed are granulated according to the required The particle...

Embodiment 2

[0286] 1. Raw materials (based on 1000g dry microcapsules)

[0287] Palm oil (the first layer of wall material) 200g (concentration 100%);

[0288] WPI (second layer wall material) 350g (concentration 11%);

[0289] Palm oil (the third layer of wall material) 200g (concentration 100%);

[0290] Bacteria powder 250g;

[0291] Curing agent solution: 0.5mol / L, pH-4.6

[0292] Starch: temperature 40°C, concentration 10%

[0293] 2. Preparation method

[0294] a. Mix whey protein with water and stir at 180rpm / min at 4°C for 16 hours;

[0295] b. heat-treat the whey protein solution at 78°C, 95rpm / min, and 45 minutes;

[0296] c. Cool immediately at 0°C; store at 4°C for 16 hours;

[0297] d. Mix 137g of sodium acetate, 100ml of glacial acetic acid and 6718g of water to make a curing agent solution, adjust the pH to 4.6, add 2.9g of Tween-20, mix well and set aside.

[0298] e. Fluidized bed granulation method: Put the probiotic powder into the fluidized bed, start the air i...

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Abstract

The invention relates to a fluidized-bed spray granulation method for preparing a probiotic microcapsule and the probiotic microcapsule prepared by virtue of the method. The preparation method comprises the following steps: (1) coating a first-layer microcapsule by virtue of the fluidized-bed spray granulation method; (2) optionally coating a second-layer microcapsule; and (3) optionally coating the microcapsule obtained in the step (2) in a fluidized bed for the third time or more.

Description

[0001] References to related applications [0002] This application claims the priority of Chinese Patent Application No. 201811314765.7 submitted on November 6, 2018, and the entire content of the application is incorporated herein as a part of the specification. technical field [0003] The invention belongs to the field of food biotechnology. More specifically, the present invention relates to a probiotic microcapsule and a preparation method of the probiotic microcapsule. Background technique [0004] Probiotics, as a kind of living microorganisms that can promote the health of the host, have multiple physiological functions in treatment and health care. However, during actual production, storage, and transportation, probiotics are affected by food components (acids, additives, etc.), ambient temperature, and host digestive system (gastric acid, enzymes, bile salts, etc.), resulting in a significant drop in the number of viable bacteria , the number of viable bacteria ...

Claims

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Application Information

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IPC IPC(8): A23L33/135A23P10/30A23P10/35
CPCA23L33/135A23P10/30A23P10/35A23V2002/00A23V2400/133A23V2400/137A23V2400/145A23V2400/147A23V2400/143A23V2400/151A23V2400/181A23V2400/165A23V2400/173A23V2400/125A23V2400/513A23V2400/515A23V2400/517A23V2400/519A23V2400/175A23V2400/529A23V2400/113A23V2400/169A23V2400/533A23V2400/249A23V2200/224A23V2200/236A23V2200/3204A23V2250/022A23V2250/18A23V2250/54252A23V2300/10A23V2250/5118
Inventor 石红丽任宪峰张志尧张杰俞伟祖马莉石涵羽樊梦原郑利君王慧李源李文清白皓雪皇永胜王旭
Owner INNER MONGOLIA MENGNIU DAIRY IND (GRP) CO LTD
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