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Antiviral urea cream compound preparation

A technology of compound preparation and urea cream, which is applied in the field of medicine, achieves the effect of definite curative effect, reducing the impact of skin barrier function damage, and stabilizing the process

Inactive Publication Date: 2020-05-22
AFFILIATED HOSPITAL OF JIANGNAN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, through literature search, there is no antiviral urea cream compound preparation type hand cream or body lotion with dual effects of skin care and antivirus both at home and abroad at present.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Prescription composition: The oil phase of this product is: stearic acid 110g, liquid paraffin 70g, vaseline 20g; the water phase is urea 110g, interferon 2 million IU, rhubarb extract 150mg, triethanolamine 18g, glycerin 60g, distilled water to volume 1000ml. Work together to make an oil-in-water cream.

[0017] Preparation: Take the oil phase ingredients, put them in a suitable container, heat them in a water bath to melt and keep them warm at about 65-80°C, take another water phase ingredient, put them in another beaker, heat them in a water bath to dissolve them, and keep them warm at about 65-80°C, slowly add the water phase In the oil phase, stir continuously in the same direction until it is semi-solid.

Embodiment 2

[0019] Prescription composition: The oil phase of this product is: stearic acid 115g, liquid paraffin 150g, lanolin 15g; the water phase is urea 140g, interferon 3 million IU, rhubarb extract 100mg, triethanolamine 18g, glycerin 40g, distilled water to volume to 1000ml. Work together to make an oil-in-water cream.

[0020] Preparation: Take the oil phase ingredients, put them in a suitable container, heat them in a water bath to melt and keep them warm at about 65-80°C, take another water phase ingredient, put them in another beaker, heat them in a water bath to dissolve them, and keep them warm at about 65-80°C, slowly add the water phase In the oil phase, stir continuously in the same direction until it is semi-solid.

Embodiment 3

[0022] Prescription composition: The oil phase of this product is: stearic acid 115g, liquid paraffin 120g, vaseline 15g; the water phase is urea 140g, interferon 3 million IU, rhubarb extract 120mg, triethanolamine 18g, glycerin 45g, distilled water to volume 1000ml. Work together to make an oil-in-water cream.

[0023] Preparation: Take the oil phase ingredients, put them in a suitable container, heat them in a water bath to melt and keep them warm at about 65-80°C, take another water phase ingredient, put them in another beaker, heat them in a water bath to dissolve them, and keep them warm at about 65-80°C, slowly add the water phase In the oil phase, stir continuously in the same direction until it is semi-solid.

[0024] The evaluation of curative effect and safety is carried out to the prepared hand cream below:

[0025] 1. Finished product quality inspection:

[0026] (1) General inspection: take appropriate amount of each of 3 batches of finished products, and insp...

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PUM

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Abstract

The invention discloses a novel antiviral urea cream compound preparation. The novel antiviral urea cream compound preparation is used for moisturizing hand skin and preventing virus infection for broad public, especially clinical medical personnel working in the front line of epidemic prevention and disease treatment. The novel antiviral urea cream compound preparation with stable process, exactcurative effect and good safety is screened and prepared through experiments by taking urea, interferon and rheum officinale as main components and adding matrixes at the same time. The antiviral ureacream compound preparation provided by the invention is used as a hand cream for external use on the hand skin, can play a dual role in protecting the skin and preventing viruses, and greatly reducesthe possibilities of infection and transmission of various viruses through the hand skin.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an antiviral urea cream compound preparation. Background technique [0002] The skin is the largest external organ of the human body and plays an important role in barrier protection. Hands are the most exposed parts to the outside world, and their skin is exposed to various substances every day. Because of the need for cleaning, they often need to be cleaned many times a day. Especially for the majority of medical staff working in the clinical frontline, strict hand hygiene operations are required. After washing for the first time, the skin of the hands is prone to dryness, peeling, and even chapping, which not only affects the appearance, but also seriously damages the barrier protection of the skin, which is easy to cause the invasion of various pathogens. At present, our country is in a special stage of fighting against novel coronavirus pneumonia. Due to the ne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/64A61K8/42A61Q19/00A61P31/12A61P17/00A61K38/21A61K9/06A61K36/708A61K31/17
CPCA61K8/42A61K8/64A61K9/0014A61K9/06A61K31/17A61K36/708A61K38/21A61K47/44A61Q19/00A61K8/9789A61P17/00A61P31/12A61K2300/00
Inventor 董达科王国华
Owner AFFILIATED HOSPITAL OF JIANGNAN UNIV