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Traditional Chinese medicine composition for sobering up and preparation method thereof

A composition and technology of traditional Chinese medicine, which are applied in the field of traditional Chinese medicine composition for hangover and its preparation, can solve the problems of insignificant improvement of drunkenness symptoms, slow hangover speed, and low content of active ingredients of medicines, etc.

Inactive Publication Date: 2020-06-02
陶玉华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are many anti-alcohol products on the market, but the effect is not good, the speed of anti-alcohol is slow, and the protective effect on multiple systems of the human body other than the liver is weak, and the improvement of drunk symptoms is not obvious; in terms of preparation technology, most products use a single Extraction methods or preparation methods such as simple pulverization into tablets and pellets; the content of active ingredients in the product is low, or due to the limitation of the extraction process of active ingredients, the insoluble ingredients are lost; or due to the volume and dosage of raw materials, lignin, cellulose There are more ingredients in the drug, resulting in less active ingredients in the unit volume, which affects the hangover effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] The raw materials of the traditional Chinese medicine composition for hangover are 30 parts of kudzu root, 30 parts of kudzu flower, 3 parts of Hovenia dulcis, 2 parts of medlar, 2 parts of schisandra, 2 parts of licorice, 30 parts of weeping grass, 30 parts of Patrinia. 3 parts of tangerine peel, 4 parts of jujube seed, 1 part of Shichangpu;

[0055] The preparation method comprises the following steps:

[0056] Prepare the raw materials according to the above-mentioned raw material composition ratio;

[0057] Soak kudzu root, kudzu flower, weeping grass and Patrinia in water for 2 hours, then use water as a solvent to carry out normal pressure extraction respectively to obtain kudzu root extract, kudzu flower extract, weeping grass extract and Patrinia extract; kudzu root, kudzu flower, weeping grass and Patrinia are flakes, and the mass ratio of water to water is 1:8, and a total of 2 extractions are carried out, each extraction time is 1.5 to 2.0 hours, twice The ...

Embodiment 2

[0067] The raw materials of the traditional Chinese medicine composition for hangover are 25 parts of kudzu root, 35 parts of kudzu flower, 2 parts of Hovenia dulcis, 3 parts of medlar, 1 part of schisandra, 3 parts of licorice, 25 parts of weeping grass, 35 parts of Patrinia. 2-parts of tangerine peel, 5 parts of jujube seed, 1 part of calamus;

[0068] Preparation method is with embodiment 1, and difference is:

[0069] (1) Negative pressure extraction is carried out after soaking; the mass ratio of kudzu root, kudzu flower, weeping grass or Patrinia to water is 1:9, each extraction time is 1.0 to 1.5 hours, and the working pressure during extraction is -0.06 to -0.08MPa;

[0070] (2) Filtration adopts centrifugal filter coarse filtration, ceramic membrane ultrafiltration and hollow fiber membrane nanofiltration successively;

[0071] (3) The quality of the concentrate is 22% of the total mass of the purified filtrate;

[0072] (4) The amount of disintegrating agent added...

Embodiment 3

[0076] The raw materials of the traditional Chinese medicine composition for hangover are 35 parts of kudzu root, 25 parts of kudzu flower, 4 parts of Hovenia dulcis, 1 part of medlar, 3 parts of schisandra, 1 part of licorice, 35 parts of weeping grass, 25 parts of Patrinia. 4 parts of tangerine peel, 3 parts of jujube seed, 2 parts of calamus;

[0077] Preparation method is with embodiment 1, and difference is:

[0078] (1) Ultrasonic extraction is carried out respectively after soaking; Pueraria lobata, Pueraria japonica, Patrinia and Patrinia are first crushed to a particle size below 5mm, and traditional Chinese medicine ultrasonic extraction equipment is used, and the extraction time is 25 to 35 minutes each time; Pueraria lobata, Pueraria japonica, The mass ratio of weeping grass or Patrinia to water is 1:9;

[0079] (2) The quality of the concentrate is 24% of the total mass of the purified filtrate;

[0080] (3) The amount of disintegrating agent added is 3% of the ...

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Abstract

The invention discloses a traditional Chinese medicine composition for sobering up and a preparation method thereof. Raw material ingredients of the traditional Chinese medicine composition comprise 15 parts to 50 parts of radix puerariae, 15 parts to 50 parts of pueravia flowers, 1 part to 6 parts of hoveniae semoveniae semen, 1 part to 6 parts of fructus lycii, 1 part to 6 parts of fructus schisandrae chinensis, 1 part to 6 parts of radix glycyrrhizae, 15 parts to 50 parts of herba sedi, 15 parts to 50 parts of herba patriniae, 1 part to 6 parts of tangerine peel, 1 part to 10 parts of semenziziphi spinosae and 1 part to 3 parts of grassleaved sweetflag rhizomes. The method comprises the following steps: (1), preparing the raw materials; (2), soaking the radix puerariae, the pueravia flowers, the herba sedi and the herba patriniae with water, and carrying out extraction to obtain radix puerariae extracting solutions, extracting solutions of pueravia flowers, herba sedi extracting solutions and herba patriniae extracting solutions; (3), mixing the extracting solutions and then performing filtration; (4), performing evaporating to prepare concentrated solutions; (5), drying the hoveniae semoveniae semen, the fructus lycii, the fructus schisandrae chinensis, the radix glycyrrhizae, the tangerine peel, the semen ziziphi spinosae and the grassleaved sweetflag rhizomes to obtain adried product, pulverizing the dried product, finely grinding the dried product, and performing ultra-micro pulverization to obtain ultra-fine mixed powder; and (6), mixing the ultra-fine mixed powder with the concentrated solutions to obtain a mixture, and adding a binding agent and preservatives into the mixture to obtain aggregates; and pressing the aggregates into tablets. According to the method disclosed by the invention, the production efficiency can be effectively improved, absorption of active ingredients is improved, the onset time is shortened, and the drug efficacy is enhanced; and the product is convenient to carry and provides convenience for oral administration and application.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for relieving alcoholism and a preparation method thereof. Background technique [0002] Alcohol consumption plays an important role in our daily lives. Alcohol can cause more than 200 diseases and injuries, including alcohol dependence, liver cirrhosis, tumors and cardiovascular diseases, mental illness, and injuries caused by violence, traffic accidents and collisions. [0003] Alcoholism is commonly known as drunkenness. After alcohol enters the human body, 30% is absorbed through the stomach, 70% is absorbed in the upper part of the small intestine, and transported to the liver and other organs and tissues through the blood; more than 90% of the alcohol entering the human body is metabolized through the liver. , first transformed into acetaldehyde, then transformed into acetic acid, and finally decomp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P39/02
CPCA61K36/41A61K36/484A61K36/488A61K36/57A61K36/72A61K36/725A61K36/752A61K36/79A61K36/815A61K36/84A61K36/888A61K2236/331A61K2236/51A61P39/02A61K2300/00
Inventor 陶玉华
Owner 陶玉华