Amisulpride impurity and preparation method thereof
A technology for amisulpride and impurities, which is applied in the field of amisulpride impurities and its preparation, can solve the problems that the synthesis method has no literature reports, etc., and achieve the effects of simple operation, short reaction route and mild reaction conditions
Active Publication Date: 2020-06-12
NANJING HEALTHNICE MEDICAL TECH +2
5 Cites 0 Cited by
AI-Extracted Technical Summary
Problems solved by technology
View more
Abstract
The invention belongs to the technical field of medicinal chemistry, in particular to an amisulpride impurity and a preparation method thereof. The preparation method comprises the following steps: inthe co-existence of a condensing agent and an activating agent, a compound I is subjected to a self-condensation reaction at the temperature of 10-70 DEG C, and a compound crude product shown as a formula (II) is prepared, wherein the molar ratio of the compound I to the condensing agent is 1: (0.4-0.7), the molar ratio of the compound I to the activating agent is 1: (0.4-0.7), and the specific is shown as follows.
Application Domain
Organic chemistryOrganic compound preparation +1
Technology Topic
Combinatorial chemistryPharmaceutical Substances +4
Image
Examples
- Experimental program(1)
- Comparison scheme(3)
Example Embodiment
PUM


Description & Claims & Application Information
We can also present the details of the Description, Claims and Application information to help users get a comprehensive understanding of the technical details of the patent, such as background art, summary of invention, brief description of drawings, description of embodiments, and other original content. On the other hand, users can also determine the specific scope of protection of the technology through the list of claims; as well as understand the changes in the life cycle of the technology with the presentation of the patent timeline. Login to view more.
Similar technology patents
Preparation method of thifluzamide key intermediate, namely 2,6-dibromo-4-(trifluoromethoxy)aniline
Owner:YANCHENG LIMIN CHEM
Method for extracting vitexin from mung bean hulls
Owner:HENAN UNIV OF SCI & TECH
Method for Oligomerizing Olefins
Owner:SK GEO CENTRIC CO LTD +1
Catalyst for preparing 1,4-cyclohexane dimethanol as well as preparation method and application thereof
Owner:CHANGZHOU UNIV
Method for preparing large-particle lithium carbonate from salt lake lithium-rich brine
Owner:QINGHAI INST OF SALT LAKES OF CHINESE ACAD OF SCI
Classification and recommendation of technical efficacy words
- short reaction path
- High yield and purity
Preparation method of high-purity DOPO (9,10-dihydro-9-oxa-10- phosphaphenanthrene-10-oxide) derivative
ActiveCN103408594Ashort reaction path
Owner:JIANGSU YOKE TECH
New method for preparing solid lignin quaternary ammonium salt and application of solid lignin quaternary ammonium salt
Owner:CHINA TOBACCO JIANGSU INDAL
Method for synthesizing 2, 5-dichloro-phthaldialdehyde
Owner:XUZHOU HUARI CHEM IND
Synthetic method for N, N-disubstituted-2-hydroxyl aliphatic amide compound
Owner:浙江交通科技股份有限公司 +1
Method for preparing 2,6-dimethylnaphthalene from isoprene and methyl p-benzoquinone
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI