Resorbable implant material made from magnesium or a magnesium alloy
A technology of implant materials and magnesium alloys, which is applied in the field of implant materials and its manufacturing, can solve the problems of complex detection and high cost
Active Publication Date: 2020-06-16
ヘルムホルツツェントルムヘレオンゲーエムベーハー
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Problems solved by technology
[0005]
However, a disadvantage of existing implants is that, so far, their absorption can only be traced via X-ray or CT inspections, which are relatively complex and costly
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[0007] Fluorescent Naval Nights (FND) is known protein markers, such as K.Merchand and S.K.SARKAR, IEEE Journal of Slected Topics in Quantum Electronics, Vol.22, No.3, May / June 2016. So far, these have been used for visualized biological cells. Fluorescent nano diamonds are harmless in biology and provide stable emissions in the near-infrared range due to the nitrogen center (NV center).
[0008] The NV center in diamonds consists of a nitrogen atom, which replaces the carbon atom in diamond lattice, as well as direct adjacent vacancy in the diamond lattice. This empty lack makes the NV center can have negative (NV — Center) or neutral (NV 0 The charge of the center. The NV center of diamonds has non-extraordinary photophysical properties.
[0009] In the case of biometric imaging, the negative NV — The center of extraordinary nature is an optically excited between 480 nm to 580 nm, thereby emitting a wide-proof band with approximately 700 nm. Excited life is approximately 17ns,...
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Abstract
The present invention relates to a resorbable implant material made from magnesium or a magnesium alloy and to a method for producing said resorbable implant material. A disadvantage of known resorbable implants is that the resorption thereof hitherto could be tracked only by means of x-ray or CT examinations. According to the invention, a resorbable implant material is provided which comprises fluorescent nanodiamonds homogeneously distributed in a matrix of magnesium or a magnesium alloy. Fluorescent nanodiamonds are harmless to the organism and provide stable emission in the near-infrared range because of nitrogen vacancies (nitrogen-vacancy centers, N-V centers). This enables the detection of the implant material in the blood plasma of the patient. According to the invention, the resorbable implant material according to the invention is produced by a method in which magnesium or a magnesium alloy is melted, nanodiamonds are added to the melt, and the melt of magnesium or a magnesium alloy provided with nanodiamonds is subjected to an ultrasound treatment.
Description
Technical field [0001] The present invention relates to an implant material made of magnesium or magnesium alloy and a method of producing thereof. Background technique [0002] In veterinary and human medicine, treatment of long bone fractures is made of medical implants made of medical steel or titanium. However, the mechanical properties of these implants are harder than bones, which may cause stress masking. Due to these and other reasons, this implant is usually removed after its function is completed, which will make patients weak due to the desired anesthesia and new tissue trauma. [0003] The absorbable implant is more concerned about fracture treatment. The purpose here is to adjust the implant by slowly reducing its stability as the healing bone intensity. To date, the best use of absorbable implants made of different polymers have not yet achieved their strength in the stressed bones. In contrast, magnesium and its alloys have a bone elastic modulus and good stretchin...
Claims
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IPC IPC(8): A61L27/04A61L27/08A61L27/42A61L27/58A61L31/02A61L31/12A61L31/14
CPCA61L27/047A61L27/08A61L27/427A61L27/58A61L31/022A61L31/024A61L31/124A61L31/148A61L2300/442A61L2400/12A61K49/005A61K49/0067C22C1/02C22C23/00
Inventor 哈乔·迪仁格
Owner ヘルムホルツツェントルムヘレオンゲーエムベーハー