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Dendrobii officinalis caulis for assisting in reducing blood sugar and application

A Dendrobium candidum, hypoglycemic technology, applied in the field of medicine and health, can solve problems such as not found, achieve good results, and assist the effect of hypoglycemic effect

Inactive Publication Date: 2020-06-30
顶诚医药科技(厦门)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Have not found yet at present, only use Dendrobium candidum as raw material to assist hypoglycemic and application

Method used

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  • Dendrobii officinalis caulis for assisting in reducing blood sugar and application
  • Dendrobii officinalis caulis for assisting in reducing blood sugar and application
  • Dendrobii officinalis caulis for assisting in reducing blood sugar and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A preparation method of dendrobium officinale powder bag, comprising the steps of:

[0024] (1) Wash the fresh stem section of Dendrobium candidum, drain and set aside;

[0025] (2) Drained Dendrobium officinale is placed in a freeze-drying device, and frozen for 2-4 hours below 0 °;

[0026] (3) Under low temperature, Dendrobium candidum is coarsely crushed with a coarse crusher, crushed into a coarse powder with a particle size of 5-10 mm, then finely crushed with a knife-type fine crusher, and crushed into a fine powder with a particle size of 20-80 mesh;

[0027] (4) keep the dendrobium candidum fine powder obtained under the low temperature and carry out ultrafine pulverization with a GMP airflow mill, and obtain the dendrobium candidum cell wall-broken ultrafine powder;

[0028] (5) The superfine powder of dendrobium candidum cell wall breaking is made into bags, each bag is 2.5 ± 0.1g.

Embodiment 2

[0030] Pharmacodynamic test:

[0031] 1 Experimental materials

[0032] 1.1 Animals

[0033] 256 healthy adult male mice of SPF grade Kunming, weighing 26±2g.

[0034] 1.2 Test samples and reagents

[0035] Embodiment 1 of the present invention, blood glucose test paper

[0036] 2 Experimental grouping and drug administration method

[0037] They were blank group, model group and treatment group.

[0038] Blank group and model group: give pure water;

[0039] Treatment group: the medicines prepared in Example 1 were given respectively, once a day with water orally, 1 pack each time.

[0040] Administration method: intragastric administration once a day for 30 consecutive days.

[0041] 3 Experimental methods

[0042] 3.1 Modeling

[0043] After fasting for 24 hours, the mice were given intraperitoneal injection of alloxan (120mg / kg BW) once to establish the model. After 5 days of fasting for 4 hours, blood was taken from the inner canthus of the eyes to measure blood...

Embodiment 3

[0063] The effect and the effect of medicated wine of the present invention are further exemplified below by 3 cases.

[0064] 1. Wang, male, 60 years old, had high blood sugar. Take Dendrobium candidum powder, 2.5±0.1g per bag, take after boiling water, 2 times a day, 1 bag each time. Results After taking it for three days, the fasting blood sugar dropped from 11.2mmol / L to 6.6mmol / L without recurrence.

[0065] 2. Lin, female, 61 years old, had high blood sugar. Take Dendrobium candidum powder, 2.5±0.1g per bag, take after boiling water, 2 times a day, 1 bag each time. Results After taking it for three days, the fasting blood sugar dropped from 11.8mmol / L to 7.1mmol / L without recurrence.

[0066] 3. Wu, male, 65 years old, with high blood sugar. Take Dendrobium candidum powder, 2.5±0.1g per bag, take after boiling water, 2 times a day, 1 bag each time. Results After taking it for three days, the fasting blood sugar dropped from 12.2mmol / L to 7.5mmol / L without recurrence...

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Abstract

The invention discloses dendrobii officinalis caulis for assisting in reducing blood sugar and an application. Only dendrobii officinalis caulis is used as the raw material for assisting in reducing blood sugar. The invention relates to the application only using the dendrobii officinalis caulis for assisting in reducing blood sugar. Other components are not added, so that the dendrobii officinalis caulis is safe and free from side effect, and can achieve favorable effect of assisting in reducing blood sugar.

Description

technical field [0001] The invention relates to the field of medicine and health, in particular to a dendrobium officinale which assists in lowering blood sugar and its application. Background technique [0002] Diabetes mellitus (DM) is a group of clinical syndromes caused by both genetic and environmental factors, with the clinical manifestation of glucose metabolism disorder. It is caused by insulin deficiency alone or in combination with insulin action disorder, which causes metabolic disorders of the three major substances, water and electrolytes; clinically, chronic hyperglycemia is the main feature, and the main clinical symptoms are polyphagia, polydipsia, polyuria, and weight loss. Performance. [0003] At present, diabetes has become the third major chronic disease that seriously endangers human health after cardiovascular and cerebrovascular diseases and tumors in the world. According to the latest statistics from Nature magazine in 2012, there are about 90 mill...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P3/10A61K135/00
CPCA61K36/8984A61P3/10A61K2236/15
Inventor 方祖开
Owner 顶诚医药科技(厦门)有限公司
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