Thin-layer tissue blood oxygen imaging method and device based on Lambert-Beer's law
An imaging method and tissue image technology, applied in the field of biomedicine, can solve problems such as inability to apply to skin surface or tissue blood oxygen saturation, high misjudgment rate, etc., achieving high real-time performance, high accuracy, and avoiding blood contamination effects.
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Embodiment 1
[0039] Such as figure 1 As shown, the embodiment of the present invention provides a thin-layer tissue blood oxygen imaging method based on Lambert-Beer's law, the method includes the following steps:
[0040] S101. Control the light source to sequentially emit the first wavelength λ 1 light, the second wavelength λ 2 light and the third wavelength λ3 the light;
[0041] S102. Collecting data at the first wavelength λ respectively 1 light, the second wavelength λ 2 light and the third wavelength λ 3 The images of the thin-layer tissue to be measured under the irradiation of the light are sequentially recorded as the first thin-layer tissue image, the second thin-layer tissue image and the third thin-layer tissue image;
[0042] S103. According to the first thin-layer tissue image, the second thin-layer tissue image, and the third thin-layer tissue image, calculate and obtain the blood oxygen distribution of the thin-layer tissue to be measured by using a preset blood oxyg...
Embodiment approach
[0076] As a possible implementation, the experimental calibration method is specifically:
[0077] In the air, an n*n detector array is fixed at a preset position away from the light source, and the first wavelength λ is measured by the detector array 1 The two-dimensional light intensity distribution of Second wavelength λ 2 The two-dimensional light intensity distribution of the light is third wavelength λ 3 The two-dimensional light intensity distribution of the light is then there is In order to ensure the accuracy of detection, the larger the value of n, the better the accuracy, for example, it can be set as a 10*10 detector array.
[0078] Since the blood oxygen saturation value is between 0 and 1, as a possible implementation, the above step S104 is specifically: mapping the blood oxygen distribution of the thin-layer tissue to be measured between 0 and 255 to form a gray scale Figure to display.
Embodiment 2
[0080] Correspondingly, an embodiment of the present invention also provides a thin-layer tissue blood oxygen imaging device based on Lambert-Beer's law, which is used to implement the above method. The device includes: a control unit 201 , an image acquisition unit 202 , a blood oxygen distribution calculation unit 203 and a display unit 204 . in:
[0081] The control unit 201 is used to control the light source to sequentially emit the first wavelength λ 1 light, the second wavelength λ 2 light and the third wavelength λ 3 light; the image acquisition unit 202 is used to collect the light at the first wavelength λ respectively 1 light, the second wavelength λ 2 light and the third wavelength λ 3 The images of the thin-layer tissue to be measured under the irradiation of light are sequentially recorded as the first thin-layer tissue image, the second thin-layer tissue image and the third thin-layer tissue image; the blood oxygen distribution calculation unit 203 is used ...
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