A composition for preventing neonatal breastmilk jaundice, its preparation method and application

A technology of composition and pharmaceutical preparation, which is applied in the field of composition for preventing neonatal breastmilk jaundice and its preparation, can solve the problems that the cause of breastmilk jaundice is not completely clear, and achieve clinical drug safety, optimized preparation process, and stable quality Effect

Active Publication Date: 2022-03-01
LIAONING HUANREN PHARMA
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The cause of breastmilk jaundice is not yet fully understood

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A composition for preventing neonatal breastmilk jaundice, its preparation method and application
  • A composition for preventing neonatal breastmilk jaundice, its preparation method and application
  • A composition for preventing neonatal breastmilk jaundice, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0053] In yet another specific embodiment of the present invention, a preparation method of the above-mentioned composition for preventing neonatal breast milk jaundice is provided, the method comprising:

[0054] S1, preparation of deer horn cream superfine powder inclusion compound;

[0055] S2. Preparation of volatile oil clathrate and water extract 1;

[0056] S3. Prepare water extract 2.

[0057] In yet another specific embodiment of the present invention, the specific method of step S1 includes:

[0058] S1.1 Ultrafine powder the antler cream to control the particle size of the antler cream D95≤10μm;

[0059] S1.2 After mixing β-cyclodextrin with water, add the superfine powder of antler cream of S1.1 to it for inclusion, and obtain the inclusion compound of superfine powder of deer horn cream; the superfine powder of the medicinal material can effectively improve the human body's ability to treat the medicinal material Absorption rate, and then use β-cyclodextrin to ...

Embodiment 1

[0083] A composition for preventing neonatal breastmilk jaundice, the composition is composed of the following raw materials in parts by weight:

[0084] 40 parts of Astragalus, 30 parts of Rehmannia glutinosa, 40 parts of Qumai, 40 parts of Codonopsis pilosula, 30 parts of white peony, 30 parts of Bupleurum, 40 parts of angelica, 30 parts of Chuanxiong and 20 parts of antler cream;

[0085] Preparation methods include:

[0086] S1, preparation of deer horn cream superfine powder inclusion compound;

[0087] S2. Preparation of volatile oil clathrate and water extract 1;

[0088] S3. Prepare water extract 2.

[0089] Wherein, the specific method of step S1 includes:

[0090] Take deer horn cream and pulverize it with a pulverizer to obtain ordinary Chinese medicine powder; then pulverize the ordinary powder with a vibrating ultrafine pulverizer for 1.5 hours, and measure its particle size distribution with a Mastersizer 2000 laser diffraction particle size analyzer, repeat t...

Embodiment 2

[0096] A kind of pellet medicine for preventing neonatal breastmilk jaundice, the preparation method of said pellet medicine is as follows:

[0097] The antler cream superfine powder clathrate, volatile oil clathrate, water extract 1 and water extract 2 prepared in Example 1 were mixed uniformly, and were pulverized into fine powder through vacuum belt drying, and compressible starch and The water-based soft material is made into pellets by extrusion-spheronization.

[0098] Wherein, the add-on of compressible starch is 45% of fine powder quality;

[0099] The adding amount of described water is 40% of fine powder quality.

[0100] The specific method of vacuum belt drying is as follows: vacuum degree -100KPa, temperature in zone one is 120°C, temperature in zone two is 100°C, temperature in cooling zone is 30°C, feed pump is 15Hz, and crawler belt is 20Hz;

[0101] The specific method of the extrusion-spheronization method is as follows: add the soft material to the extrusi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a composition for preventing neonatal breastmilk jaundice, a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. The composition is composed of the following raw materials in parts by weight: 35-45 parts of Radix Astragali, 25-35 parts of Rehmannia glutinosa, 35-45 parts of Qumai, 35-45 parts of Codonopsis pilosula, 25-35 parts of Radix Paeoniae Alba, 25-35 parts of Bupleuri 35 parts, 35-45 parts of angelica, 25-35 parts of Chuanxiong and 15-25 parts of antler cream. The present invention optimizes the combination of multi-flavored natural traditional Chinese medicines and optimizes the product preparation process, so that the pharmaceutical composition of the present invention can be suitable for pregnant women to take before giving birth, and then be used to prevent neonatal jaundice. At the same time, the present invention is preferably made into a micropill dosage form, and the micropill prepared by the preparation method of the present invention has stable quality and is safe and effective for clinical use. It has the value of good practical application and the prospect of industrial application.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a composition for preventing neonatal breastmilk jaundice, a preparation method and application thereof. Background technique [0002] The information disclosed in this background section is only intended to increase the understanding of the general background of the present invention, and is not necessarily taken as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to those skilled in the art. [0003] With the improvement of breastfeeding rate, the incidence of breastmilk jaundice increases year by year, and has reached 20% to 30% at present. It has also become one of the main causes of hyperbilirubinemia in hospitalized newborns. Although the prognosis of this disease is good, only severe cases need treatment, but it should also be paid attention to in order to promote breastfeeding smoothly...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61P1/16A61K35/32
CPCA61K36/481A61K36/804A61K36/36A61K36/344A61K36/71A61K36/65A61K36/233A61K36/232A61K36/236A61K35/32A61P1/16A61K2236/37A61K2236/331A61K2236/39A61K2236/51A61K47/6951A61K2300/00
Inventor 郑继宇李国栋杨玉周书繁汪巍罗红王辉
Owner LIAONING HUANREN PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap