23 results about "Newborn jaundice" patented technology

The invention discloses a neonatal jaundice health management system based on big data, and belongs to the technical field of jaundice health management, and the system specifically comprises the steps: collecting the transdermal jaundice measurement value, hemoglobin concentration, day age and weight data of a neonate through a data collection module; an individualized drift index is calculated based on the hemoglobin concentration and the day age data through a physiological parameter calibration module; inputting the transdermal jaundice measurement numerical value and the individualized drift index into a dynamic correction model through a dynamic prediction analysis module to generate a serum bilirubin prediction numerical value; a time sequence data processing module is used for smoothing the predicted numerical value and calculating the variable quantity of adjacent time points; constructing trend indexes and generating serum bilirubin change trend data through a trend analysis and detection module; and finally, generating a health management scheme based on the threshold level and the trend change point through an intelligent decision module. According to the invention, effective assessment and personalized management of the neonatal jaundice risk are realized.

The invention discloses a semi-supervised non-contact neonatal jaundice home intelligent early warning method based on image calibration, and the method comprises the steps: building a camera response function database, and building a color constancy depth model and a skin region segmentation network; designing a strong and weak enhancement strategy by using a large amount of label-free home data, constructing a time and context comparison learning module, and performing self-supervised training on a feature encoder; a small amount of labeled hospital data and a large amount of unlabeled family data are combined, and semi-supervised fine tuning is realized through pseudo label generation and supervised comparative learning; image sequences continuously uploaded by a user are input into the model, multi-day prediction of the bilirubin level is achieved, prediction uncertainty is quantified in combination with a Bayesian method, the risk boundary is dynamically adjusted, and personalized early warning is provided. According to the method, a user does not need to use a physical colorimetric card, color measurement errors caused by model differences of mobile equipment and variability of household illumination are inhibited from a data source, and the accuracy and robustness of subsequent jaundice assessment are improved; through a training framework combining self-supervised pre-training and semi-supervised fine tuning, the understanding ability and generalization performance of the model for the sequential characteristics of jaundice are improved.

The application discloses an animal bifidobacterium producing bile salt hydrolase and application thereof in neonatal jaundice, and belongs to the technical field of microorganisms. The animal bifidobacterium lactis WXM screened by the application has the effect of relieving neonatal jaundice, can significantly improve weight loss of a jaundice individual in an early life stage, improve abnormal increase of a bilirubin level in serum, improve liver damage, improve the level of an enzyme related to liver function, the expression level of a related inflammatory factor in the liver and the expression level of an enzyme UGT1A1 related to bilirubin metabolism, and has the effect of relieving neonatal jaundice. The strain of the application has high safety and has wide application value in the fields of food, functional food, health products, medicine and the like.

1. Name of the product in this design: Portable neonatal jaundice treatment device. 2. Purpose of this design: For the treatment of neonatal jaundice. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The invention relates to the technical field of neonatal jaundice monitoring, in particular to a neonatal jaundice follow-up monitoring system. The system obtains bilirubin concentration data of a current newborn; according to the similar condition of the daily bilirubin concentration data between the historical newborn and the current newborn, obtaining a matching day of the current day of the historical newborn and the current day of the current newborn; the newborns with pathological jaundice in the historical newborns are used as a first category, the newborns with non-pathological jaundice are used as a second category, and bilirubin concentration data in the current day of the current newborn and the matching day of the historical newborns in each category are determined according to the similar condition of the bilirubin concentration data in the current day of the current newborn; and obtaining the category of the current day of the current newborn so as to determine the jaundice severity of the current day of the current newborn. By comparing the bilirubin concentration data of the current newborn with the bilirubin concentration data of the historical newborn, the jaundice severity of the current newborn can be accurately analyzed in real time, and the jaundice problem of the current newborn can be solved in time.

1. The name of the design product: platform type neonatal jaundice treatment instrument. 2. The use of the design product: for neonatal jaundice treatment. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

This invention discloses a smart bracelet for monitoring neonatal jaundice, relating to the field of neonatal medical monitoring and nursing technology. It includes a bracelet storage box and a lid hinged to the surface of the storage box. A battery plate is fixedly installed at the bottom of the inner wall of the storage box, and a flame-retardant partition is fixedly installed in the middle of the inner wall. The surface of the flame-retardant partition has a bracelet groove and multiple storage slots. This invention uses transcutaneous jaundice values ​​as trigger conditions, combined with the core logic of adaptive sleep depth analysis, changing the traditional disconnect between jaundice and sleep monitoring. By preset clinically recognized bilirubin thresholds, it can automatically and without manual intervention initiate precise tracking of the key neurological symptom of "drowsiness" when jaundice reaches a risk level, achieving early and objective warning of acute bilirubin encephalopathy and buying valuable time for medical intervention.

1. The name of the design product: neonatal jaundice treatment lamp. 2. The use of the design product: for treating neonatal jaundice. 3. The design features of the design product: in the shape of the product. 4. The picture or photo that best indicates the design features: perspective view.

The invention belongs to the field of medical treatment, and particularly relates to a neonatal jaundice treatment incubator with a pacifying device, the neonatal jaundice treatment incubator comprises a supporting seat, the top of the supporting seat is fixedly connected with a transparent box, one end of the transparent box is of a portal structure capable of being rotatably opened, and the top of the transparent box is fixedly connected with a power table; a blue light irradiation module and a uniform exhaust module are mounted at the bottom of the power table, an adjusting bed is mounted at the bottom of the inner side of the transparent box, and adjusting arms are mounted on the two sides of the transparent box; through the arrangement, the treatment environment of the newborn is improved, health problems caused by long-term treatment are reduced, manual operation is not needed, labor cost and pressure are reduced, when the emotion of the newborn is worsened, the newborn can be gently pressed and swung through the adjusting arms, the rhythm of a mother is simulated, and the sedation effect is achieved; the treatment quality is further improved.

A phototherapy garment for treating jaundice includes a base garment configured to conform to a patient's body and includes a stretchable textile substrate, a plurality of conductive traces integrated into the base garment, and a plurality of light-emitting diodes (LEDs) oriented to direct light toward a wearer's skin. Methods of treating jaundice using the phototherapy garment and methods of manufacturing the phototherapy garment further define characteristics of the phototherapy garment.

The invention relates to the technical field of neonatal non-invasive medical monitoring, in particular to a non-invasive neonatal jaundice monitoring method and system.The light reflection measuring unit adopts the design of dual-wavelength alternate emission and an inclination angle light source, the mirror reflection of fetal fat is inhibited, and the measurement accuracy is improved; a dual-wavelength reflected light intensity ratio is converted into an original percutaneous bilirubin value, a fetal fat analysis unit accurately recognizes a fetal fat area and calculates the coverage degree through multispectral imaging and a convolutional neural network, a dynamic pressure sensing unit monitors contact pressure in real time and triggers an acousto-optic alarm when a standard interval is exceeded, an intelligent calibration processing unit calls a three-dimensional lookup table, and the coverage degree is calculated. And through bilinear interpolation matching correction coefficients, superposition of fetal age and measurement part compensation factors and output of a corrected percutaneous bilirubin value, the interference of fetal fat reflection and pressure fluctuation is eliminated, accurate non-invasive monitoring is realized, and a reliable basis is provided for clinical diagnosis of neonatal jaundice.

The invention discloses a baby carriage with a neonatal jaundice illumination nursing function. The baby carriage includes a frame, a cabin mounted on the frame, and a light barrier assembly disposed above the cabin. The light barrier assembly is provided with a blue light band selective transmission layer, and the transmission layer is configured to perform spectrum screening on natural light or ambient light irradiated to the baby carriage. The spectrum screening has a band-pass filtering characteristic: treatment wave band light with the wavelength ranging from 400 nm to 550 nm is allowed to penetrate through, and ultraviolet light with the wavelength smaller than 400 nm and visible light and infrared light with the wavelength larger than 550 nm are blocked or attenuated. The optical coating structure and the light energy conversion material are utilized, harmful components in natural light are accurately filtered out without an external power source, only effective treatment light is reserved to enter a cabin, safe and convenient jaundice auxiliary nursing under the outdoor scene is achieved, and the problems that a mother and an infant are separated and depend on a power source due to traditional phototherapy are solved.

1. The name of the design product: cabin type neonatal jaundice treatment instrument. 2. The use of the design product: for neonatal jaundice treatment. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external treatment pharmaceutical preparation for neonatal jaundice and a preparation method thereof. The external treatment medicinal preparation for neonatal jaundice comprises the following raw materials in parts by weight: 14-28 parts of oriental wormwood, 12-23 parts of scabiosa, 9-18 parts of ficus sarmentosa, 6-15 parts of potentilla discolor, 5-13 parts of poria cocos, 3-10 parts of astragalus membranaceus, 2-6 parts of immature bitter orange and 3-7 parts of liquorice. Test results show that the external treatment pharmaceutical preparation for the neonatal jaundice, which is prepared by the invention, can be smeared on the planta pedis of the neonatal, so that the total serum bilirubin level of each group of child patients can be remarkably reduced, and the total cure rate of clinical treatment is improved, and therefore, the external treatment pharmaceutical preparation has a remarkable treatment effect on the neonatal jaundice and has a wide application prospect.

AI-BASED NEWBORN JAUNDICE TREATMENT DEVICE

The present application relates to the technical field of non-invasive medical monitoring of newborns, in particular, the present application relates to a non-invasive jaundice monitoring method and system for newborns, in the present application, the light reflection measurement unit adopts a dual-wavelength alternate emission and tilt angle light source design, suppresses the fetal grease mirror reflection, converts the dual-wavelength reflection light intensity ratio into the original transcutaneous bilirubin value, the fetal grease analysis unit accurately identifies the fetal grease area and calculates the coverage through multispectral imaging and convolutional neural network, the dynamic pressure sensing unit monitors the contact pressure in real time, triggers the audible light warning when the value is out of the standard interval, the intelligent calibration processing unit calls the three-dimensional lookup table, matches the correction coefficient through bilinear interpolation, superimposes the gestational age and measurement site compensation factor, and outputs the corrected transcutaneous bilirubin value, eliminates the interference of fetal grease reflection and pressure fluctuation, realizes accurate non-invasive monitoring, and provides a reliable basis for clinical diagnosis of neonatal jaundice.

1. Name of the product in this design: Vertical Neonatal Jaundice Treatment Device. 2. Purpose of this design: For the treatment of neonatal jaundice. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The application discloses a new-born jaundice health management system based on big data, and belongs to the technical field of jaundice health management, and specifically comprises the following steps: collecting the transcutaneous jaundice value, hemoglobin concentration, day age and weight data of a new-born through a data collection module; calculating individualized drift indexes based on the hemoglobin concentration and day age data through a physiological parameter calibration module; inputting the transcutaneous jaundice value and the individualized drift indexes into a dynamic correction model through a dynamic prediction analysis module to generate serum bilirubin prediction values; performing smoothing processing on the prediction values and calculating the change amount of adjacent time points by using a time series data processing module; constructing trend indexes and generating serum bilirubin change trend data through a trend analysis detection module; and finally generating a health management scheme based on threshold levels and trend change points through an intelligent decision module; and the application realizes effective evaluation and individualized management of the risk of new-born jaundice.

The invention relates to the technical field of jaundice phototherapy, in particular to a portable neonatal jaundice phototherapy and body position adjustment integrated device which comprises a base and a placement box, and a phototherapy mechanism is arranged on the base; the phototherapy mechanism comprises a frame, the back wall of the frame is slidably connected with a closing plate, the frame is slidably connected with a plurality of moving frames, the moving frames are made of rubber and have shape plasticity, the moving frames are fixedly connected with mounting frames, the mounting frames are made of rigid materials, and the mounting frames are fixedly connected with the frame. The blue light lamp has the beneficial effects that the blue light lamp gets rid of the position constraint of a traditional preset connecting piece, rapid adjustment in the non-stop state is achieved, and no matter a lamp set is temporarily additionally arranged to strengthen local irradiation or a faulty lamp body is replaced, the operation is convenient, and the cost is low. The phototherapy jaundice removing can be efficiently completed without interrupting the phototherapy process, and the stability of the phototherapy jaundice removing efficiency is guaranteed.

The invention discloses a phototherapy equipment irradiance dynamic regulation and control method and system based on a neonatal jaundice index, relates to the field of irradiance dynamic regulation and control, and pre-estimates a bilirubin decline rate in an ideal state through a preset phototherapy kinetic model in combination with child patient individual baseline characteristics. In the treatment process, the real bilirubin decline rate of a child patient is monitored in real time and calculated, and the real bilirubin decline rate and an expected target value are subjected to difference comparison of physiological response dimensions. And reversely deducing the current physical attenuation coefficient of the hardware by using the difference value. And finally, acting the attenuation coefficient on an original set value, and correcting the drive output of hardware in real time by dynamically generating an irradiance compensation instruction. Therefore, automatic closed-loop regulation and control from clinical effect evaluation to hardware power compensation are realized, the influence of hardware performance fluctuation on treatment accuracy is eliminated fundamentally, and continuous stability and high efficiency of phototherapy irradiance are ensured.

The invention relates to the technical field of medical data mining, in particular to a neonatal jaundice four-level early warning system and method based on multi-modal analysis. The method comprises the steps of firstly obtaining feeding record data; further obtaining a bilirubin increment-day age-growth increment change curved surface according to the growth increment of the historical neonates of the same day age and the distribution of the corresponding bilirubin increment; historical predicted bilirubin is further obtained based on the change curved surface; further obtaining network prediction bilirubin based on the pre-trained neural network; and finally, according to the difference between the historically predicted bilirubin and the network predicted bilirubin, in combination with the difference between the historically predicted feeding interval and the network predicted feeding interval, four-level early warning of jaundice is carried out. According to the scheme, the influence of breast feeding is considered, the physiological model and the neural network are fused, dynamic personalized prediction and multi-source comparison of bilirubin are realized, the problems of poor model generalization and early warning lag in traditional jaundice monitoring are solved, and the accuracy and timeliness of jaundice risk identification are improved.

The utility model provides a cover structure for neonatal jaundice treatment bed, and the cover structure is used for covering the neonatal jaundice treatment bed, the neonatal jaundice treatment bed is equipped with control part and bed part, and the cover structure comprises: the cover structure is equipped with accommodating space, and the accommodating space is used for accommodating the neonatal jaundice treatment bed, a cooperation component is used for cooperating with the control part, and the shape of cooperation component is adapted to the shape of control part, a plurality of window parts are arranged in cooperation component, and a plurality of window parts are arranged corresponding to the control part, are used to make the part of control part and outside intercommunication, a plurality of curtain parts are arranged in cooperation component, and a plurality of curtain parts are used for shielding bed part, and are attached to each other but are not connected. The utility model makes the cover structure more adapt to the neonatal jaundice treatment bed.

This invention belongs to the field of pharmaceutical technology and relates to a novel medical use of caffeine for premature infants, specifically its application in improving jaundice in premature infants. This invention analyzes clinical data from premature infants, constructs a mouse model of jaundice, and conducts in vivo imaging and gene knockout verification experiments in premature mice. It was found that clinical caffeine treatment can effectively reduce serum bilirubin levels in premature infants; in jaundice mice and premature mouse models, caffeine intervention significantly reduces brain tissue and serum bilirubin concentrations; gene knockout mouse experiments confirmed that caffeine enhances hepatic bilirubin uptake by upregulating OATP1A / 1B. The caffeine in this invention shows a significant effect in improving neonatal jaundice. Furthermore, caffeine is a commonly used medication for premature infants, is easy to use, and is readily accepted by medical staff and families, making it suitable for relieving apnea combined with jaundice symptoms in premature infants.