49 results about "Newborn jaundice" patented technology

Methods of determining levels of unbound metabolites are disclosed. Probes derived from fatty acid binding protein muteins are described that bind preferentially to a number of unbound metabolites including oleate, stearate, linoleate, palmitate, arachidonate and unconjugated bilirubin. A profile for a patient is determined using one or more of the described probes. The profile is useful in diagnosis of disease, particularly myocardial infarction, non-alcoholic fatty liver disease (NAFLD), diabetes, stroke, sepsis and neonatal jaundice. The responses of multiple probes to a test sample are used to classify the degree of acute coronary syndrome by comparison to multi-probe profiles generated from unstable angina, non ST elevation myocardial infarction, and ST elevation myocardial infarction.

The invention discloses a neonatal jaundice recognition device, equipment and system based on artificial intelligence. The device collects a large number of historical neonatal jaundice images and extracts the features of the images to obtain training samples and inputs the training samples into a fine-grained classification model for training to obtain a neonatal jaundice recognition model. Lastly, a camera shoots a current neonatal jaundice image, the target features of the image are extracted according to the feature extraction method, and then the target features are introduced into the trained neonatal jaundice recognition model, thereby obtaining the jaundice level corresponding to the image. Thus it can be seen that the device can achieve recognition of neonatal jaundice, prevents auser from going to and from the hospital, reduces general expenses and has higher efficiency. The neonatal jaundice recognition equipment based on the artificial intelligence corresponds to the abovedevice, and therefore, the equipment has the above advantages.

The invention discloses a direct bilirubin determination kit and a preparation method and application thereof. The problem that jaundice interferes with direct bilirubin determination in specimens of the newborn is solved. A direct bilirubin determination kit body and Emulgen A-90 and / or Emulgen B-66 are provided. By means of the direct bilirubin determination kit, it can be effectively avoided that the jaundice of the newborn interferes with specimen detection, and the problem that false determination results of the specimens due to the jaundice of the newborn are a bit more is solved, so that the detection accuracy of the specimens of the newborn jaundice is greatly improved.

The invention discloses a neonatal jaundice therapeutic instrument. On the basis of real-time monitoring of the bilirubin concentration in blood of the newborn, the treatment efficiency of the neonatal jaundice can be improved substantially. The neonatal jaundice therapeutic instrument is characterized in that one end of a cable connector is connected to a photoelectric source case and the other end of the cable connector is connected with a blue-light treatment blanket by an optical fiber hose. The blue-light treatment blanket consists of a light transmitting layer, a light leakage layer, a reflective layer and a constant temperature layer; optical fibers and fabric filaments are knitted, woven, or wound to form the light leakage layer; and the constant temperature layer is made of a material with a melting point of 30 to 38 DEG C. A jaundice detection module connected with the photoelectric source case electrically is used for feeding back real-time monitoring data of bilirubin in the blood of the newborn to the photoelectric source case. The neonatal jaundice therapeutic instrument is suitable for the newborn nursing after delivery, especially for treatment of diseases like the neonatal jaundice and serves as one of necessary devices of a delivery room, a newborn room, or a newborn monitoring center.

The invention relates to a blue light irradiation bed for pediatric jaundice treatment. The bed comprises a bottom rack, a swinging mechanism, a height adjusting mechanism, a movable rack, a baby bed and a blue light irradiation mechanism. The blue light irradiation bed for pediatric jaundice treatment can solve the following problems in the treatment process of neonatal jaundice: a, in the traditional pediatric jaundice treatment process, the blue light irradiation effect is influenced due to unconscious turning of a newborn in the blue light irradiation process, thus the blue light irradiation is not uniform, the irradiation time of blue light on the surface of the newborn body is influenced, and the neonatal jaundice treatment effect is affected; and b, in the traditional pediatric jaundice treatment process, the newborn needs to be turned over frequently to ensure that the front and back of the newborn are irradiated by blue light, the area of the newborn irradiated by the blue light is larger, however, as the newborn is poor in autonomous consciousness and cannot turn over by himself, the newborn needs to turn over manually by nurses, and the workload is large.

The invention relates to the technical field of jaundice treatment equipment, in particular to a newborn jaundice treatment instrument. The newborn jaundice treatment instrument comprises a base (1),a housing (2) which is snap fitted to the base (1) and a light guiding assembly which is connected with the base (1), wherein a light source assembly (12), a cooling module assembly (13), a fan(14), awind channel separating plate (113) and a power source module are sequentially arranged on the inner side of the base (1) from top to bottom; and a ventilation hole (1131) is formed in the wind channel separating plate (113), and is formed in a wind sucking opening of the fan(14). According to the newborn jaundice treatment instrument disclosed by the invention, the elements in the machine body of the jaundice treatment equipment are reasonable in layout; and the wind channel separating plate is arranged, so that the situation that air repeatedly circulates in the machine body is avoided, andthe heat dissipation effect is better.

The invention relates to the technical field of neonatal jaundice treatment equipment, in particular to a neonatal jaundice treatment box convenient for a remote mobile phone app to follow up data, which comprises a treatment box, bases are vertically welded at four corners of the lower end surface of the treatment box, and a treatment inner cavity is formed in the middle of the upper end surfaceof the treatment box. A monitor and a therapeutic instrument are fixedly arranged on the left side and the right side of the upper end face of the treatment box respectively, and the newborn baby incubator has the beneficial effects a transparent bottom plate is arranged at the upper end of an LED lamp, so that a newborn baby is prevented from making direct contact with the LED lamp, and meanwhilebuffering of illumination of the LED lamp is achieved; the newborn is prevented from being directly stimulated by illumination, and the protection of the newborn is greatly improved; the signal transmission device is arranged on the monitoring device, so that the monitored data is transmitted to the cloud in real time, medical staff can remotely download and monitor the treatment condition of thetreatment box conveniently, the working efficiency of the medical staff is greatly improved, meanwhile, the treatment process is recorded, and data storage and statistics are facilitated.

The invention discloses a traditional Chinese medicine rectum instillation preparation for treating neonatal hyperbilirubinemia. Traditional Chinese medicine holds that the neonatal hyperbilirubinemia belongs to the field of jaundice, yang jaundice and newborn jaundice. The preparation is prepared from the following traditional Chinese medicinal materials with effects of clearing damp-heat of liver and gall, bitter-cold for purging and inducing diuresis: small-leaved desmodium, pumpkin flower, swertia mileensis, farges catalpa bark, chrysosplenium sinicum maxim, isodon amethystoides, indochinese cassia fruit, thlaspi arvense, smilax riparia and patience dock root. Clinical tests prove that the preparation has a remarkable curative effect.

The invention provides a blue-light fluorescent powder in an LED device for the treatment of neonatal jaundice, and a synthetic method thereof. The chemical composition formula of the blue-light fluorescent powder is SiO2-Mg1xCl2: Eu<2+>x, wherein 0.001<=x<=0.90. The synthetic method of the above blue-light fluorescent powder comprises the steps of calcinating MgO, SiO2 and Eu2O3 at 500-1000 DEG C in the air atmosphere for 1 to 5 hours to form a fluorescent powder A; grinding the fluorescent powder A, and calcinating the ground fluorescent powder A at 500-1000 DEG C in the reducing atmosphere for 1 to 5 hours to form the final blue-light fluorescent powder. The above reactions are conducted in a ceramic crucible and a tube-type reducing furnace. Firstly, the obtained fluorescent powder is of a quartz-type structure, and the raw materials of the fluorescent powder are non-toxic, cheap and easy to obtain. The synthetic method of the fluorescent powder is conducted based on the high-temperature solid-phase reaction, and has the advantages of simple synthetic method, short synthesis time and the like. Secondly, the ultraviolet content of a product of the invention accounts for less than a thousandth of the overall fluorescence emission quantity thereof. The radiation range required for the illumination treatment of neonatal jaundice is perfectly covered. Meanwhile, the energy utilization rate and the safety are improved.

The invention discloses a traditional Chinese medicine composition for preventing ABO maternal-fetal blood group incompatibility. Infant jaundice caused by the ABO maternal-fetal blood group incompatibility mostly belongs to the scope of fetal jaundice and newborn jaundice of traditional Chinese medicine, and the key is preventive treatment during progestation and pregnancy for the infant jaundice. The composition adopts the following traditional Chinese medicines: Japanese angelica tree root bark, orchis, black soybean coat, parmelia tinctourium, thalictrum aquilegiifolium, astragalus bhotanensis, axillary choerospondias bark, dioscorea subcalva prain et bur-kill, dryland willow leaves, hempleaf negundo chastetree leaves and nothapodytes pittosporoides which are decocted by water into decoction. Clinical trials show that a total effective rate of the composition is 98%, and is obviously better than that of 70% of a control group, and the composition has a significant curative effect.

The invention discloses traditional Chinese medicine enema for treating hyperbilirubinemia of newborn. The hyperbilirubinemia of newborn belongs to traditional Chinese medicine fetal jaundice-newborn jaundice, and the theory of traditional Chinese medicine thinks that the newborn jaundice is caused by the weakness of the spleen and the stomach, dampness-heat fumigation or dampness and hotness obstruction and biliary excretion blockage of a fetus in the maternal body. The traditional Chinese medicine enema for treating the hyperbilirubinemia of newborn is prepared from traditional Chinese medicines comprising wintergreen barberry root, pilosella-leaved drymoglossum herb, japanese xylosma bark, senna, common clearweed herb, creeping rostellularia herb, mile swertia, smallflower epipactis herb, rust-coloured crotalaria herb with root and smallflower seaberry herb, and the traditional Chinese medicines are prepared into enema. The clinic test proves that each index is better than the control group, and the curative effect is obvious.

The invention discloses a laser therapy house intelligent system for neonatal jaundice treatment. In particular, a blue laser serves as a light source, and the laser is transmitted to different beds through optical fibers and beam expanding is carried out in a step-by-step power distribution mode; an intelligent monitoring and control system is configured at the same time, a medical staff knows the condition of each child patient through a bed display screen and a remote electronic device, and effective nursing is carried out timely. The stable light source of the blue laser and the step-by-step optical fiber beam expanding method are used for regulating the power of a treatment unit, and personalized treatment in view of different conditions is realized; the condition changes and the conform of the child patient are monitored in real time through the intelligent system, thereby realizing a more humanized nursing mode. The innovation points are that the accurate laser source is adopted, and the operation is safe and efficient; the systematic treatment room is used, and management is facilitated; remote and real-time monitoring is carried out, and timely nursing is facilitated; and the comfort of the child patient is focused, and a personalized and intelligent treatment scheme is realized.

The invention provides a traditional Chinese medicine drug for treating neonatal jaundice and a preparation method thereof. The traditional Chinese medicine drug is prepared by mixing and smashing 13-18 parts by weight of bark and leaves of abelia macrotera (Graebn. et Buchw.) Rehd. and 2-3 parts by weight of herba artemisiae scopariae, extraction is conducted, and patches or injections or smearing preparations or oral preparations are obtained to treat the neonatal jaundice. The traditional Chinese medicine drug is prepared from pure natural plants, essence is taken, the drug properties are fully exerted, the curative effect is significant, and no toxic or side effect exists. The distribution of raw materials is wide, collection is convenient, the preparation method is simple, the cost is low, and the effect is significant.

The invention relates to an intelligent evaluation system and equipment for neonatal jaundice, and a storage medium. The system comprises: a feature extraction module for acquiring feature information of symptom change of the neonatal jaundice by using a TextRank algorithm; a feature classification module which is used for constructing a reference feature information classification library of physiological jaundice, pathological jaundice and breast milk jaundice; a symptom acquisition module which is used for acquiring feature information of the change of the neonatal jaundice symptom to be identified by using a TF-IDF word segmentation technology; a preliminary matching module which is used for preliminarily acquiring a corresponding reference feature information classification library in a keyword combination retrieval mode based on the feature information of the to-be-identified neonatal jaundice symptom change; and an intelligent evaluation module which is used for calculating the similarity between the to-be-identified neonatal jaundice feature information and the reference feature information, and evaluating whether the neonatal jaundice is affected or not according to a similarity matching result. According to the invention, neonatal jaundice intelligent cognition is carried out, pathogenesis can be reasonably positioned, and a basis is provided for neonatal jaundice diagnosis and treatment.

The invention provides a traditional Chinese medicine composition for preventing neonatal jaundice. The traditional Chinese medicine composition is prepared from the following crude drugs in parts by weight: 100 parts of flos lonicerae, 100 parts of radix scutellariae and 100 parts of fructus gardeniae. A preparation form of the medicine can be capsules, granules, tablets or powder. Based on clinical research, the security and the effectiveness of the traditional Chinese medicine composition for preventing the neonatal jaundice are verified; medicine flavor of the composition is little, the quality is easy to control, and the cost is also low. The traditional Chinese medicine composition is applied to the preparation of the traditional Chinese medicine composition for preventing the neonatal jaundice.

The invention discloses a traditional Chinese medicine composition for treating neonatal jaundice, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following Chinese herbal medicines of capillary wormwood herb, large-leaved gentian, astragalus root, giant knot weed, rhizome of Chinese atractylodes, plantain seed, honeysuckle, dried ginger, root of hairy asiabell and licorice root. The traditional Chinese medicine composition has the advantages that by utilizing all Chinese herbal medicines according to the prescription, the effects of clearing heat and detoxifying, and removing dampness and relieving jaundice are realized, and the neonatal pathologic jaundice can be treated; the symptoms of a neonatal patient, such as skin yellow staining, sclera yellowing and yellow urine, can be effectively relieved, the bilirubin level of the neonatal patient is obviously decreased, the neonatal jaundice is quickly eliminated, and the function of treating the neonatal jaundice is realized; after clinical proofing, compared with prior art, the traditional Chinese medicine composition has the advantages that the compatibility is concise, the treatment process is short, the treatment effect is good, the curative rate is obviously better than the curative rate of the traditional Chinese medicine at existing market, and the traditional Chinese medicine composition is suitable for being popularized and applied.

The invention relates to a meconium metabolism marker and a screening method and application thereof, the meconium metabolism marker is used for evaluating neonatal jaundice, and the meconium metabolism marker comprises valine, leucine and isoleucine. The valine, the leucine and the isoleucine are closely related to the neonatal jaundice, and the occurrence of the neonatal jaundice can be reliably judged by detecting the metabolic markers. Therefore, whether the neonates are prone to jaundice or not can be judged at the first time only by detecting meconium excreted by the newly born neonates, relevant monitoring and intervention are carried out in time, judgment does not need to be carried out two or three days after the neonates are born, and early discovery, early intervention and early treatment are truly achieved.

The invention provides a composition for preventing neonatal breastmilk jaundice, a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. The composition is composed of the following raw materials in parts by weight: 35-45 parts of Radix Astragali, 25-35 parts of Rehmannia glutinosa, 35-45 parts of Qumai, 35-45 parts of Codonopsis pilosula, 25-35 parts of Radix Paeoniae Alba, 25-35 parts of Bupleuri 35 parts, 35-45 parts of angelica, 25-35 parts of Chuanxiong and 15-25 parts of antler cream. The present invention optimizes the combination of multi-flavored natural traditional Chinese medicines and optimizes the product preparation process, so that the pharmaceutical composition of the present invention can be suitable for pregnant women to take before giving birth, and then be used to prevent neonatal jaundice. At the same time, the present invention is preferably made into a micropill dosage form, and the micropill prepared by the preparation method of the present invention has stable quality and is safe and effective for clinical use. It has the value of good practical application and the prospect of industrial application.

The invention discloses an identification method and device for simply detecting neonatal jaundice disease risk, and relates to the technical field of picture identification. The method comprises thefollowing steps: S1, acquiring an initial value; collecting a face image of a newborn, processing the image through a conversion process to obtain an HSV color value, and recording the HSV color valueas A1, and similarly, in the same scene, obtaining an HSV color value of the reference object, and recording the HSV color value as B1; s2, obtaining a detection value; in a new environment, collecting a baby face image, processing the image through a conversion process to obtain an HSV color value, and recording the HSV color value as A2; similarly, in the same scene, obtaining an HSV color value of the reference object, and recording the HSV color value as B2; s3, judging and analyzing; and when the absolute value of (a-b) is greater than or equal to the threshold value, judging that the jaundice condition is abnormal, otherwise, judging that the jaundice value is normal. The invention is based on on-line image recognition, wherein the real-time jaundice condition of the newborn is judged by collecting the environment condition of the newborn discharged from a hospital and the current face data of the newborn, and the current jaundice risk is estimated.

The invention provides a jaundice monitoring method and device. Applied to a server, the method includes: receiving a calibration image sent by an image acquisition terminal and a skin image of a monitoring object; determining a jaundice monitoring value according to the calibration image, the skin image, and a pre-trained jaundice prediction model; The jaundice monitoring value is fed back to the image acquisition terminal. The embodiment of the present invention provides convenience for real-time monitoring of neonatal jaundice symptoms, provides support for doctors' real-time diagnosis and decision-making, and ensures the health and life of newborns.

The invention discloses a special spectrometer for a neonatal jaundice blue light therapeutic instrument and an optical mechanism design method of the special spectrograph. The special spectrometer comprises a box body, an optical mechanism located in the box body and a drive circuit module, wherein a slit for light transmission is formed in the top surface of the box body, and the optical mechanism comprises a collimating mirror, a grating, a focusing mirror and a CCD detection module; and the drive circuit module comprises a signal conditioning circuit module, an ADC analog-to-digital converter, an FPGA system, a USB control chip and an upper computer which are connected in sequence. According to the special spectrograph applied to the blue light therapeutic instrument, by changing the position of the slit and the corresponding design of the optical mechanism, the redundant function is omitted, the equipment size is reduced, the cost is reduced, the responsibility to the wavelength within the blue light range is improved, the required wavelength can be better matched, and the using effect is increased.

The invention provides a body position adjusting device for a blue light treatment instrument for neonatal jaundice, and relates to the technical field of blue light treatment instruments. The body position adjusting device for the blue light treatment instrument for neonatal jaundice comprises a first transverse plate, a rotating rod is arranged at the top of the first transverse plate, the outer side of the rotating rod is rotationally connected with a second gear and a fourth gear through one-way damping bearings, and the top of the second gear is connected with a first gear in an engaged mode. According to the body position adjusting device for the blue light treatment instrument for neonatal jaundice, a vertical rod moves downwards to drive a hiccup beating block to move downwards, milk hiccup beating is conducted on a baby, when a fifth gear and a sixth gear lose the meshing state, a transverse rod is driven to rotate reversely under the force of a torsion spring of a clockwork spring, an outer frame moves upwards to drive the hiccup beating block to move upwards, the structure is beneficial for beating milk hiccups of the baby, and the situation that the baby is held up to beat the milk hiccups, so that time and labor are wasted, and the treatment time and the treatment effect of the baby are delayed is avoided.

The invention relates to the technical field of medical instruments, and discloses a special percutaneous jaundice instrument for newborns and a monitoring method of the special percutaneous jaundice instrument. The special percutaneous jaundice instrument comprises a percutaneous jaundice instrument shell, wherein an intelligent chip internally integrated with a detection system and a storage battery used for providing electric energy are sequentially and fixedly mounted in the percutaneous jaundice instrument shell from left to right, a liquid crystal display screen used for displaying detection data of the intelligent chip and a touch screen function operation area used for operating the whole device are sequentially inlaid in the outer surface of the upper end of the percutaneous jaundice instrument shell from left to right, a detection probe used for detection is fixedly mounted at the front end of the percutaneous jaundice instrument shell, and an on-off key for controlling the on-off of the whole device is embedded in the rear side wall surface of the percutaneous jaundice instrument shell. In addition to the function of measuring the skin bilirubin value of all percutaneous jaundice instruments in the market, the special percutaneous jaundice instrument also has the function of providing reference on the treatment modes of jaundice of newborns with different gestational ages, different birth weights and different hours or day ages.

The invention relates to a jaundice elimination assisting device, in particular to a neonatal jaundice elimination assisting device. The technical problem of the invention is to provide a neonatal jaundice elimination assisting device which can provide a comfortable mimicry environment for a neonate and can carry out comprehensive irradiation. A neonatal jaundice elimination assisting device comprises a base, a treatment box, a placement plate, blue light lamps, a shaking mechanism and an irradiation mechanism, the treatment box is arranged on the base in a sliding mode, the placement plate is arranged in the treatment box, the three blue light lamps are arranged on the upper portion of the inner side of the treatment box in a sliding mode, the shaking mechanism is arranged on the base, and the irradiation mechanism is arranged on the rear side of the treatment box. The motor drives the belt pulley assembly to move, so that the treatment box shakes, and the effect of providing a comfortable mimicry environment for newborns is achieved.

The efficient pediatric jaundice treatment equipment comprises a base body, electric appliance boxes are fixedly connected to the tops of the inner walls of the two sides of the base body, treatment devices are fixedly connected to the positions, located on the two sides of the electric appliance boxes, of the top of the base body, and a control box door is arranged in the middle of the outer wall of the left side of each treatment device. The middle position of the left side of the top of the treatment device is fixedly connected with an observer, and the left side of the back face of the treatment device communicates with an oxygen supply pipe. According to the efficient pediatric jaundice treatment equipment, internal sealing can be conveniently guaranteed, meanwhile, an observer can observe various internal data and treatment states in real time, so that shaking generated when an infant is pushed is avoided, an anti-skid soft cushion is attached to the interior of a movable sleeping box, the treatment position of the infant is effectively limited, and the treatment effect of the infant is improved. The neonatal jaundice treatment agent can relieve infant skin injury, protect neonatal skin and improve the neonatal jaundice treatment efficiency.

The invention relates to diagnosis in general and more specifically a system and a method for determining the presence of jaundice in newborn babies, also known as neonatal jaundice.A main objective of the present invention is to provide a simple system and method for determining the presence of jaundice. Particularly since most deaths due to jaundice occur in low-income countries, there is a large unmet need of simple, reliable and affordable technologies able to identify at-risk newborn.The objective is accomplished through receiving a depiction of skin from an RGB sensor, and then using either an optical diffusion model of the skin or Monte Carlo simulations to calculate the bilirubin concentration. A meta model of the optical diffusion model or Monte Carlo simulations can also be used. Colour calibration is also performed by e.g. thin-plate spline interpolation.

The invention discloses a method for preparing a traditional Chinese medicine composition for treating neonatal jaundice and belongs to the technical field of traditional Chinese medicine. According to the preparing method, capillary wormwood herbs, radix gentianae macrophyllae, radix astragali, polygonum cuspidatum, rhizoma atractyloidis, semen plantaginis, honeysuckle, dried ginger, codonopsis pilosula and liquorice are smashed, mixed uniformly, extracted with water and concentrated to obtain thick paste, alcohol extracting and concentrating are carried out on filter residues to obtain thick paste, and two kinds of thick paste are combined to prepare the medicine preparation. The preparing method is simple, equipment is simple, the medicine effect is stable, universality is good, and production can be enlarged easily; in addition, the traditional Chinese medicine composition can relieve symptoms of xanthochromia, sclera jaundice, yellow urine and the like of child patients, can remarkably reduce the bilirubin level of the child patients, enables neonatal jaundice to subside fast, and has the function of treating neonatal jaundice. By means of clinical verifications, compared with the prior art, the traditional Chinese medicine has the advantages of being simple in compatibility, short in treatment course and good in curative effect, and is worthy of application and popularization, and the cure rate is remarkably higher than that of existing traditional Chinese medicine sold in the market.

The invention discloses a special spectrometer for neonatal jaundice blue light treatment instrument and its optical mechanism design method, which comprises a box body, an optical mechanism located in the box body and a drive circuit module, and the top surface of the box body is provided with a light-transmitting hole. The slit, the optical mechanism includes a collimating mirror, a grating, a focusing mirror and a CCD detection module, and the driving circuit module includes a signal conditioning circuit module, an ADC analog-to-digital converter, an FPGA system, a USB control chip and a host computer connected in sequence. The present invention designs a special spectrometer applied to the blue light therapy instrument. By changing the position of the slit and the corresponding design of the optical mechanism, it not only saves the redundant function, reduces the volume of the equipment, reduces the cost, but also improves the blue light range. The responsivity of the wavelength within can better match the required wavelength and improve the use effect.