Bedside pulmonary ventilation-blood perfusion impedance tomography method based on saline radiography

Abstract

The invention discloses a bedside pulmonary ventilation-blood perfusion impedance tomography method based on saline radiography, an image monitoring device based on the method, an image monitoring system based on the method and a pulmonary embolism diagnosis system based on the method. By means of the method, the quality of blood perfusion imaging is improved, and dead space ventilation%, intrapulmonary shunt% and regional ventilation-blood match% are calculated according to blood perfusion imaging, so that the practicability is higher. Pulmonary embolism can be diagnosed by means of the method, the sensitivity is 90.9%, the specificity is 98.6%, and the method has very high clinical application value.

Description

technical field [0001] The invention belongs to the field of clinical medicine, and in particular relates to a bedside electrical impedance tomography method based on saline contrast-enhanced lung ventilation-blood perfusion. Background technique [0002] Electrical impedance tomography (EIT) is a non-invasive imaging technique used to study and monitor regional lung ventilation and perfusion (blood flow) in humans and animals. In contrast to conventional methods, EIT does not require the patient to breathe through a tube or sensor, does not apply ionizing X-rays, and can be used for extended periods of time, such as 24 hours or even longer. Therefore, EIT can be used continuously and thus is suitable for real-time and long-term monitoring of therapeutic effects. EIT was first used to monitor respiratory function in 1983 and remains the only bedside method that allows continuous, non-invasive detection of regional changes in lung volumes, blood flow, and cardiac activity. ...

AI Technical Summary

Problems solved by technology

[0004] At present, the quality of bedside pulmonary vascular perfusion imaging based on electrical impedance technology (EIT) is poor, and it is interfered by electrical resistance signals such as heart beating and pulmonary vascular pulsation, so its clinical application is poor.

In order to improve the imaging quality, some studies have developed the electrical impedance imaging method of saline contrast technology. Saline is injected through the central venous catheter, and at the same time apnea, the change of thoracic resistance signal is collected, and the local resistance-time change curve of saline contrast is established, but the resistance- There are many types of time curve analysis methods. During the saline injection process, it is difficult to identify the arrival of saline into the right atrium, reduce the interference of the resistance signal, and affect the imaging analysis. It is difficult to obtain the accurate time point of the first arrival of saline in the lung. , to determine the inconsistency between the time when the lung resistance drops and the heart resistance drops in a certain area, but the practicability is poor and time-consuming

[0005] Bedside pulmonary blood perfusion imaging analysis, the current electrical impedance technology mostly focuses on the distribution percentage of ventilation and blood flow, which belongs to semi-quantitative evaluation, and it is technically difficult to go deep into the equivalent quantitative calculation of ventilation dead space and intrapulmonary shunt

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