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Preparation method of five-component sperm increasing soft capsules and preparation method

A technology of soft capsules and wolfberry fruit is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations containing active ingredients, which can solve the problems of difficulty in mass production, complicated processes, and high dosage, and achieve high production efficiency and quality. High controllability and good curative effect

Active Publication Date: 2020-07-28
FOSHAN SOIN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this extraction method is more complex and difficult to achieve mass production
and its consumption is still high

Method used

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  • Preparation method of five-component sperm increasing soft capsules and preparation method

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preparation example Construction

[0048] see figure 1 , the invention provides a kind of preparation method of Wuzi Yanzong soft capsule, it comprises the following steps:

[0049] S1: Extract the fruit of wolfberry with 60-80% ethanol at least once to obtain a filtrate; concentrate and dry the filtrate to obtain fruit extract powder of wolfberry;

[0050] Specifically, S1 includes:

[0051] S11: the Lycium barbarum is extracted twice with 60-80% ethanol under reflux to obtain a filtrate;

[0052] Specifically, Lycium barbarum is one of the monarch drugs in this prescription, and improving its extraction efficiency has positive significance for improving the curative effect of the prescription. Through research, it is found that the active ingredients of Lycium barbarum are mainly polysaccharides, flavonoids and alkaloids of Lycium barbarum; among them, polysaccharides have strong polarity, and their solubility in ethanol with a concentration of more than 80% is significantly reduced. Alkalis are weak in po...

Embodiment 1

[0088] The present embodiment provides a kind of preparation method of Wuzi Yanzong soft capsule:

[0089] Take 376g of Lycium barbarum, add 60% ethanol twice the weight of the medicinal material, heat and continuously reflux to extract twice, filter, and recover the ethanol from the filtrate under reduced pressure and concentrate to a thick paste with a relative density of 1.25 (65°C). Vacuum drying under reduced pressure below 70°C, crushed into fine powder to obtain Lycium barbarum extract powder.

[0090] Get 376g of Cuscuta (fried), 188g of raspberry, 94g of Plantago (fried with salt), 47g of Southern Schisandra (steamed), add 60% ethanol of 2 times the weight of medicinal materials, heat and continuously reflux for extraction twice, filter, and combine to obtain The filtrate A is ready for use; add 8 times the amount of water to the dregs, heat and boil for extraction for 1 hour, filter, concentrate the filtrate to a relative density of 1.05 (65°C), and let it cool. Add...

Embodiment 2

[0094] The present embodiment provides a kind of preparation method of Wuzi Yanzong soft capsule:

[0095] Take 352g of Lycium barbarum, add 70% ethanol twice the weight of the medicinal materials, heat and continuously reflux for extraction twice, filter, and recover the ethanol from the filtrate under reduced pressure (65°C) and concentrate to a thick paste with a relative density of 1.3 (60°C). The thick extract is vacuum-dried under reduced pressure below 60°C, and crushed into fine powder to obtain wolfberry extract powder.

[0096] Get Cuscuta (stir-fry) 352g, cross 60 mesh sieves after pulverizing, and control the sieving rate of 40%; Get Raspberry 176g, Plantaginacea (stir-fry with salt) 88g, Southern Schisandra (steam) 44g, cross 40 mesh sieves after pulverizing; Take the undersieve and mix, add 80% ethanol in an amount twice the weight of the medicinal material, heat and continuously reflux to extract twice, filter, and combine to obtain the filtrate A for use; add 6...

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Abstract

The invention discloses a preparation method of five-component sperm increasing soft capsules. The preparation method comprises the following steps: extracting fructus lycii with ethanol, concentrating and drying to obtain fructus lycii extract powder; mixing semen cuscutae, fructus rubi, semen plantaginis and fructus schisandrae chinensis, and carrying out alcohol extraction to obtain first filtrate and filter residues; carrying out water extraction and alcohol precipitation on the filter residues to obtain third filtrate, mixing the first filtrate and the third filtrate, concentrating and drying to obtain mixed extract powder; adding the fructus lycii extract powder and the mixed extract powder into a suspension, stirring and degassing to obtain liquid medicine; and jointly forming the liquid medicine and glue solution auxiliary materials to obtain finished five-component sperm increasing soft capsule soft capsules. The preparation method is high in raw material utilization efficiency, the extraction rate of effective components can be increased effectively, and excessive impurities in extracts can be avoided. The soft capsules are good in efficacy and small in dosage.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a Wuzi Yanzong soft capsule and a preparation method thereof. Background technique [0002] The prescription of Wuzi Yanzong Pills comes from Xuanjielu in Tang Dynasty. The original prescription is Wuzi Shouxian Pills. It has the functions of nourishing the liver and kidney, replenishing the essence and benefiting the marrow. It is effective for kidney deficiency, low back pain, urination, spermatorrhea, premature ejaculation, impotence and infertility. The 2015 edition of "Chinese Pharmacopoeia" listed two dosage forms of Wuzi Yanzong Pill and Wuzi Yanzong Tablet; among them, Wuzi Yanzong Tablet is made of 275g of medlar, 275g of dodder, 135g of raspberry, 35g of schisandra, and 68g of psyllium; its preparation The process is as follows: part of the dodder is finely powdered, and part of it is decocted with raspberry; the three medicinal ingredients such a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/48A61P29/00A61P1/14A61P13/12A61P15/08A61P15/10A61P13/00
CPCA61K9/4858A61K36/39A61K36/43A61K36/57A61K36/68A61K36/73A61K36/79A61K36/815A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P1/14A61P13/00A61P13/12A61P15/08A61P15/10A61P29/00A61K2300/00
Inventor 黄锦峰孟召光窦荣霞王俊付虎生
Owner FOSHAN SOIN PHARMA CO LTD
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