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Toothpaste capable of inhibiting helicobacter pylori and preparation method of toothpaste

A technology for Helicobacter pylori and toothpaste is applied in the field of toothpaste that can inhibit Helicobacter pylori and its preparation, can solve the problems of stubborn bad breath and difficult to remove, and achieves the effect of improving and relieving bad breath.

Pending Publication Date: 2020-08-18
江苏宝芝林多抗生物工程技术研究有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After being infected with Helicobacter pylori, Helicobacter pylori can cause gastritis, periodontitis, etc., thereby causing bad breath, and bad breath is very stubborn and difficult to remove

Method used

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  • Toothpaste capable of inhibiting helicobacter pylori and preparation method of toothpaste
  • Toothpaste capable of inhibiting helicobacter pylori and preparation method of toothpaste
  • Toothpaste capable of inhibiting helicobacter pylori and preparation method of toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] The toothpaste preparation method of the present embodiment is as follows:

[0046] S1. Take out the components of component B in sequence, and ultrasonically stir for 1-1.5 hours to make it evenly stirred;

[0047]S2. Take out the components of component A in sequence, then ultrasonically stir for 0.5-1 hour, then pour the stirred mixture into the mixer of S1 to mix and stir evenly, and emulsify;

[0048] S3, add component C into the mixer of S2, and continue to stir for 1-1.5 hours;

[0049] S4. Pour component D into the agitator of S3 and stir for 0.5-1 hour; if there is no component D, this step is omitted;

[0050] S5, perform homogenization, and stand for 4-8 hours to obtain toothpaste.

[0051] Prepare different toothpaste respectively according to table 1 according to preparation method of the present invention:

[0052] Table 1

[0053]

[0054]

[0055] Put each toothpaste into the toothpaste tube after it is made, because the caliber of the toothpas...

Embodiment 2

[0057] Select 100 cases of Helicobacter pylori-positive patients with bad breath (the mouth has peculiar smell or bad smell), and 100 cases of non-Helicobacter pylori-positive patients with bad breath, and divide them into five groups, with 20 cases of Helicobacter pylori-positive patients and 20 cases of non-Helicobacter pylori-positive patients in each group. Bacteria-positive patients with bad breath were named as experimental group 1, experimental group 2, experimental group 3, experimental group 4, and control group, and experimental group 1, experimental group 2, experimental group 3, experimental group 4, and control group were used and implemented The No. 1 toothpaste, No. 2 toothpaste, No. 3 toothpaste, No. 4 toothpaste, and the toothpaste of the control group in Example 1, each time in the morning and evening, each time about 1 cm (about 1g), brush your teeth with an ordinary soft-bristled toothbrush, and brush your teeth for at least 1 g each time. 5 minutes, the tes...

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Abstract

The invention discloses toothpaste capable of inhibiting helicobacter pylori and a preparation method of the toothpaste. The toothpaste is prepared from the following components in parts by weight: 27to 36.5 parts of a component A, 57 to 82 parts of a component B and 0.35 to 1.3 parts of a component C, wherein the component A is prepared from 25 to 30 parts of hydrated silica, 1 to 2.5 parts of glycerol laurate and 1 to 4 parts of cellulose gum; the component B is prepared from 40 to 55 parts of sorbitol (sugar), 0.1 to 0.4 part of IgY, 0.04 to 0.06 part of sodium pyrophosphate, 1 to 2 partsof cocamidopropyl betaine, 0.1 to 0.3 part of tetrasodium glutamate diacetate and 10 to 15 parts of water; the component C is prepared from 0.04 to 0.07 part of tranexamic acid and 0.1 to 0.4 part ofnisin. By adopting the IgY component, helicobacter pylori in the oral cavity can be effectively inhibited, so that the halitosis problem is relieved and improved. In addition, various food-grade antibacterial and antiviral components are adopted, microorganisms causing food residue rotting, tooth damage and oral inflammation in the oral cavity can be inhibited at the same time, and therefore the halitosis problem is further relieved.

Description

technical field [0001] The invention relates to daily chemical products, in particular to a toothpaste, in particular to a toothpaste capable of inhibiting Helicobacter pylori and a preparation method thereof. Background technique [0002] Toothpaste is a very common daily chemical product at present, and it mainly scrubs teeth and oral cavity by toothbrush, thereby playing the effect of cleaning teeth and oral cavity and freshening breath. However, with people's irregular work and rest, oral hygiene and other habits, it is easy to cause inflammation of the gums and oral ulcers. Therefore, many toothpaste manufacturers will add anti-inflammatory ingredients to the toothpaste, so that it can directly act on the affected area when using it for treatment and prevention. Inflammatory effect. However, most of these anti-inflammatory ingredients are medicinal ingredients, many of which are chemically synthesized raw materials, so long-term use will affect human health. [0003] ...

Claims

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Application Information

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IPC IPC(8): A61K8/24A61K8/25A61K8/34A61K8/37A61K8/44A61K8/64A61K8/73A61Q11/00
CPCA61K8/25A61K8/375A61K8/731A61K8/345A61K8/64A61K8/24A61K8/442A61K8/44A61Q11/00
Inventor 杨严俊张乔荔陈颖杨昌顺
Owner 江苏宝芝林多抗生物工程技术研究有限公司