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Feed additive, preparation method, and application of feed additive in resisting piglet diarrhea

A technology for feed additives and piglet diarrhea, applied in application, animal feed, pharmaceutical formula, etc., can solve the problems of undisclosed prevention and treatment of diarrhea, and achieve the effect of protecting the intestinal epithelial mucosa, reducing decomposition, and reducing the stimulation of external adverse factors

Inactive Publication Date: 2020-09-08
无锡利必多生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the patents on monoglyceryl laurate are more focused on the anti-mold of feed, digestion and absorption of animals, etc., and the prior art does not disclose the combination of short- and medium-chain fatty acid esters such as monoglyceryl laurate and zinc oxide. Prevent diarrhea

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A preparation method and application of a feed additive with high-efficiency anti-diarrhea in piglets, the steps are:

[0022] (1) Add 30 parts of monoglyceride laurate and 20 parts of tributyrin into the container, heat and keep stirring until the material melts;

[0023] (2) Add 20 parts of zinc oxide and stir evenly;

[0024] (3) Add 30 parts of silicon dioxide and stir evenly, take out the material and cool it to room temperature, and obtain a feed additive with high efficiency against piglet diarrhea.

[0025] 300 weaned piglets (21-28 days old) were used as experimental subjects, and were randomly divided into 3 groups, 100 piglets in each group. Experimental group 1 added 3000 mg / kg zinc oxide to the basic diet, experimental group 2 added 300 mg / kg of the above-mentioned high-efficiency anti-diarrhea feed additive to the basic diet, and the control group was only fed the basic diet. During the test period of 0 to 14 days, the diarrhea rates of the experimental ...

Embodiment 2

[0027] A preparation method and application of a feed additive with high-efficiency anti-diarrhea in piglets, the steps are:

[0028] (1) Add 20 parts of monoglyceride laurate and 20 parts of tributyrin into the container, heat and keep stirring until the material melts;

[0029] (2) Add 40 parts of zinc oxide and stir;

[0030] (3) Add 20 parts of silicon dioxide and stir evenly, take out the material and cool it to room temperature, and obtain a feed additive with high efficiency against piglet diarrhea.

[0031] A total of 450 weaned piglets (21-28 days old) were used as experimental subjects and randomly divided into 3 groups, 150 piglets in each group. Experimental group 1 added 300 mg / kg of the above-mentioned high-efficiency anti-diarrhea feed additives for piglets to the basal diet, and experimental group 2 added 300 mg / kg of monoglyceride laurate, tributyrin, zinc oxide and dioxide to the basal diet. Silicon compound was simply physically mixed according to the same...

Embodiment 3

[0033] A preparation method and application of a feed additive with high-efficiency anti-diarrhea in piglets, the steps are:

[0034] (1) Add 20 parts of monoglyceride laurate and 20 parts of tributyrin into the container, heat and keep stirring until the material melts;

[0035] (2) Add 30 parts of zinc oxide and stir evenly;

[0036] (3) Add 30 parts of silicon dioxide and stir evenly, take out the material and cool it to room temperature, and then get high-efficiency antibacterial

[0037] Feed additive for piglets with diarrhea.

[0038] Experiment 1: 450 weaned piglets (21-28 days old) were used as experimental subjects, and were randomly divided into 3 groups, 150 piglets in each group. Experimental group 1 added 100 mg / kg of the above high-efficiency anti-diarrhea feed additives for piglets to the basic diet, and experimental group 2 added 100 mg / kg of monoglyceride laurate, tributyrin, zinc oxide and dioxide to the basic diet. Silicon compound was simply physically ...

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PUM

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Abstract

The invention discloses a feed additive, a preparation method thereof and an application of the feed additive in resisting piglet diarrhea. The preparation method comprises the following steps: (1) adding glycerol monolaurate and tributyrin into a container, and performing heating until the glycerol monolaurate and tributyrin are molten; (2) adding zinc oxide and performing uniform stirring; and (3) adding silicon dioxide and performing uniform stirring. By compounding glycerol monolaurate, tributyrin and zinc oxide, a good anti-diarrhea effect can still be achieved when the usage amount is reduced by one order of magnitude compared with that of single use of glycerol monolaurate, tributyrin or zinc oxide,, and the feed additive has the advantages of low dosage and high efficiency.

Description

technical field [0001] The invention relates to the field of animal feed additives, in particular to a preparation method and application of a high-efficiency anti-diarrhea feed additive for piglets. Background technique [0002] Diarrhea is a common symptom of piglets after the onset of the disease. The incidence rate is as high as 50% to 60%. Porcine diarrhea mainly occurs in newborn piglets aged 1-3 days, suckling pigs aged 7-20 days and nursery pigs aged 4-15 days after weaning. Piglet diarrhea leads to slow growth, decreased feed return rate, and in severe cases, reduced piglet survival rate, which has brought huge economic losses to the pig industry. Therefore, it is particularly important to effectively prevent piglet diarrhea. [0003] Monoglyceride laurate, also known as monoglyceride dodecanoate, is a medium-chain fatty acid ester with a melting point of 62°C. It naturally exists in breast milk, coconut oil and American palmflower. It is a monoester formed of lau...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K20/158A23K20/20A23K50/30A23K50/60A61K33/30A61P1/12A61K31/23A61K31/22A61K33/00A01K67/02
CPCA01K67/02A61K31/22A61K31/23A61K33/00A61K33/30A23K20/158A23K20/20A23K20/30A23K50/30A23K50/60A61P1/12A61K2300/00
Inventor 杨博田爱民陈华勇蓝东明刘峥曾煜辉
Owner 无锡利必多生物科技有限公司
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