Method for detecting purity of thioorganic arsenic finished product
A detection method and technology for finished arsenic products are applied in the field of detection of the purity of thioorganic arsenic products, which can solve the problems of underestimation, poor stability of thioorganic arsenic, and misjudgment of the nature of the sample itself.
Active Publication Date: 2020-12-18
JIANGHAN UNIVERSITY
View PDF9 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Due to the poor stability of thioorganoarsenic, there is no commercial standard product, and laboratory synthetic samples are often used in scientific research for follow-up experiments. After the existing forms are separated, the percentage of the response value of this form to the total response value of all forms is used for rough estimation
However, the response sensitivity of different arsenic species in the equipment is not exactly the same, therefore, this rough quantification method may underestimate or overestimate the content of sulfur-containing organoarsenic compounds in synthetic samples, which may lead to the inconsistency of the samples themselves in subsequent studies. Misjudgment of nature
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0068] Step 1. Configuration of the actual sample:
[0069] Accurately weigh 5mg DMMTA respectively V Synthetic samples and 5 mg DMDTA V Synthetic samples (Cullen, W.R.; Liu, Q.; Lu, X.; McKnight-Whitford, A.; Peng, H.; Popowich, A.; Yan, X.; Zhang, Q.; Fricke, M.; Sun , H., Methylated and thiolated arsenic species for environmental and health research—A review on synthesis and characterization. Journal of Environmental Sciences, 2016, 49, 7-27.), to DMMTA V Add 1 mL of 2% chloroform / ultrapure water, DMDTA to synthetic samples V Add 1mL of 2% ethanol / ultrapure water to the synthetic sample to help dissolve (chloroform and ethanol are both used as help solvents), vortex appropriately, and place an ultrasonic cleaner to gently sonicate to help dissolve until the powder is completely dissolved, and prepare 5mg / mL DMMTA respectively V Synthetic sample stock solution and 5mg / mL DMDTA V Synthetic sample mother liquor.
[0070] Step 2, use inductively coupled plasma mass spectro...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention belongs to the technical field of thio-organic arsenic finished product detection, and particularly relates to a method for detecting the purity of a thio-organic arsenic finished product. The method comprises the following steps: respectively dissolving a DMMTAV finished product and a DMDTAV finished product in water or an organic solvent to obtain a DMMTAV finished product to-be-detected solution and a DMDTAV finished product to-be-detected solution, detecting the solutions through HPLC-ICP-MS, and determining the response factors x and y of the DMMTAV and the DMDTAV in the HPLC-ICP-MS according to a binary linear equation set by combining total arsenic content, other arsenic component content and response value data. The detection method is easy to operate and good in controllability and repeatability, wherein recovery and determination of all separation forms of the compound are omitted, and the content and purity information of the compound can be obtained while formanalysis is performed, so that the problem of accurate analysis of purity of non-labeled compounds DMMTAV and DMDTAV finished products is solved.
Description
technical field [0001] The invention belongs to the technical field of detection of thioorganoarsenic finished products, and in particular relates to a detection method for the purity of thioorganoarsenic finished products. Background technique [0002] Due to natural or artificial sources, arsenic is widely distributed in various environmental media and is a toxic pollutant that seriously affects human health and has a potential carcinogenic risk. There are many kinds of arsenic metabolites, the sample matrix is complex, and the metabolic intermediates are unstable. Thioorganoarsenic compounds are a new class of arsenic metabolites discovered recently, among which the toxicity of monothiodimethylarsenic acid is equivalent to that of the more toxic arsenous acid, and monothiodimethylarsenic acid and dithiodi Methyl arsenic acid, two currently discovered and detected thioorganoarsenic compounds, can be transformed into each other. Therefore, it is necessary to further stud...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/34G01N30/72G01N30/86
CPCG01N30/02G01N30/34G01N30/7233G01N30/8675
Inventor 龙艳敏钟慧芳陈程雷梦瑾凌倩倩蔡勇
Owner JIANGHAN UNIVERSITY