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Human organ blood oxygenation system

A technology for blood oxygenation and human organs, applied in the field of blood oxygenation system of human organs, can solve the problems of inability to remove toxins, low level, and inability to effectively preserve severed limbs for a long time, so as to promote wound healing and ensure biochemical The effect of the indicator

Active Publication Date: 2021-01-01
BEIJING SHIJITAN HOSPITAL CAPITAL MEDICAL UNIVERSTY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional mechanical perfusion systems mimic physiological conditions to a lesser extent
[0007] In recent years, a large number of studies have used low temperature combined with organ perfusion fluid to preserve severed limbs, and achieved good results, but they cannot effectively preserve severed limbs for a long time, nor can they remove a large amount of toxins produced by tissue necrosis of severed limbs before replantation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Example 1 A human organ blood oxygenation system

[0065] Such as figure 1 As shown, the blood oxygenation system of human organs includes extracorporeal circulation transfers 1 and 5, membrane oxygenator 2, gas generator or cylinder 3, blood storage device 4, blood purification device 6, replacement fluid 7, and extracorporeal circulation circuit 8. Its working process: the venous blood of the human body is drained from the extracorporeal circulation line 8 to the blood storage device 4, and the oxygen in a special ratio is passed through the membrane oxygenator 2 to oxygenate the venous blood by using the gas generator or the gas cylinder 3, and then the Extracorporeal circulation transitions 1 and 5 drive the blood to undergo extracorporeal circulation, and the oxygenated blood will undergo ion exchange with a specially proportioned replacement fluid 7 in the blood purification device 6, and finally enter the human arterial system. Circulating blood will monitor te...

Embodiment 2

[0070] Example 2 A human organ blood oxygenation system

[0071] Such as figure 2 As shown, the blood oxygenation system of human organs includes extracorporeal circulation transfer 2-1, membrane oxygenator 2-2, blood purification device 2-3, sterile table 2-4, heparin pump 2-5, blood pressure sensor 2 -6, temperature control device 2-7. Extracorporeal circulation turning machine 2-1 is a centrifugal pump, which provides power for blood circulation, ensures continuous extracorporeal blood perfusion, and reduces the number of damaged red blood cells. The membrane oxygenator 2-2 is a membrane lung, which plays a part of cardiopulmonary replacement and maintains the oxygenation of limb tissues. The blood purification device 2-3 filters the inflammatory media and metabolic waste in the extracorporeal circulation blood to purify the blood. Sterile bench 2-4: Provide a sterile environment. Heparin pumps 2-5 continuously pump heparin into the circulation to prevent blood clottin...

Embodiment 3

[0076] Example 3 A human organ blood oxygenation system

[0077] Such as image 3 As shown, the human physiological data monitoring and detection device, such as the automatic blood gas detection device 3-1 and the automatic biochemical detection device 3-2, can detect PH, electrolyte, lactic acid, urea, creatinine, etc. in the circulating fluid, when the automatic blood gas detection device 3- 1 and the automatic biochemical detection device 3-2 detect that the above-mentioned value is too high or too low, through an intelligent remote control device such as an automatic detection control system 3-0, mobilize the gas regulating device 3-14 to adjust the blood gas of the circulating fluid, and mobilize the ion regulation Device 3-15, for preliminary correction of the ion level in the circulating fluid. The circulating fluid passes through the blood purification device such as the filter device 3-3, adjusts the ratio and flow rate of the replacement fluid to automatically corr...

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Abstract

The invention provides a human organ blood oxygenation system which comprises an extracorporeal circulation rotating machine, a membrane oxygenator and a blood purification device, the extracorporealcirculation rotating machine is used for replacing a heart to pump blood, the membrane oxygenator is used for replacing a lung to carry out oxygenation, and the blood purification device is used for replacing part of functions of a liver and a kidney; the human organ blood oxygenation system drives human venous blood through the extracorporeal circulation rotating machine, performs oxygenation inthe membrane oxygenator, drains the blood to the blood purification device to perform ion exchange with replacement liquid, and finally infuses the blood to a human tissue blood circulation system toestablish local blood circulation. According to the system, the survival ability of tissues is improved by oxygenating venous blood of human organs, toxic shock and acute renal failure after re-plantation are reduced by utilizing toxins generated by the extracorporeal blood purification device before re-plantation of broken limbs, and the system can also be used for treating lung diseases including but not limited to infectious lung diseases, such as corona virus disease.

Description

technical field [0001] The invention relates to a maintenance system of human organs, in particular to a blood oxygenation system of human organs. Background technique [0002] 2019-nCoV infection most commonly involves the respiratory system, resulting in pneumonia. Severe (including severe and critical) patients are characterized by respiratory failure and may be accompanied by heart, kidney, intestinal and other organ damage. Respiratory support therapy is the main treatment for respiratory failure. High-flow nasal cannula oxygen therapy or non-invasive mechanical ventilation is often ineffective, and invasive mechanical ventilation cannot solve the problem in critical cases. [0003] The shortage of donors in heart and lung transplantation has always been a bottleneck in the advancement of transplantation technology. Many patients who need organ transplantation have to wait for a long time for the appearance of a donor, and most patients eventually die because they cann...

Claims

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Application Information

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IPC IPC(8): A01N1/02
CPCA01N1/0247
Inventor 王江宁
Owner BEIJING SHIJITAN HOSPITAL CAPITAL MEDICAL UNIVERSTY
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