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Oral care composition and application

An oral care and composition technology, applied in the field of oral care, can solve problems such as unpleasant astringent taste and restrictions on the use of zinc salts, and achieve the effect of reducing astringent taste and increasing residence time

Active Publication Date: 2021-02-05
HAWLEY & HAZEL BVI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although zinc ions in a soluble state have been widely used in oral care compositions, when zinc ions in a soluble state are included in oral care compositions , there will be an unpleasant astringent taste, which limits the use of zinc salts in oral care products

Method used

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  • Oral care composition and application

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment

[0080] Evaluation method of astringent taste

[0081] 1) Establishment of the evaluation team

[0082] Select 30 qualified sensory evaluators with reference to GB / T 16291.1-2012 and GB / T12311-2012;

[0083] 2) Correction of the astringency evaluation standard by the scoring standard evaluator

[0084] Accurately weigh 0.010g, 0.025g, and 0.05g of grape tannins, add them into 500ml of pure water and stir evenly, then dilute to 1L with pure water. Strength is 0 points;

[0085] Take 20 mL of the above-mentioned reference sample solution, gargle fully for 30 seconds, and then spit it out (do not gargle with water), and evaluate the intensity of the astringent taste inside the cavity at this time. Repeat the measurement of the reference sample three times, and take the average of the three results, so that the evaluators can remember their own scoring strength. Then, according to the comprehensive re-scaling method stipulated in the value estimation method of the national stan...

Embodiment 1

[0088] Embodiment 1, comparative examples 1-2

[0089] According to table 1 formula configuration comparative example 1-2, embodiment 1:

[0090] Table 1 (percentages in the form are percentages by weight)

[0091]

[0092] As can be seen from Table 1, only a thickener of cellulose gum was added in Comparative Example 1, and the detectable concentration of soluble zinc in the formula was 25ppm; while in Comparative Example 2, the detectable concentration of soluble zinc increased To 45ppm; Embodiment 1 increases the carbomer on the basis of comparative example 2, simultaneously for the viscosity of stabilizing paste, reduces the consumption of cellulose glue, and the detectable concentration of soluble zinc is the same as that of comparative example 2 is equivalent to 47ppm.

[0093] Judging from the astringent taste evaluation results, when the detectable concentration of soluble zinc is only 25ppm, the subject does not feel the astringent taste of the paste; but when th...

Embodiment 2-6， comparative example 5

[0101] According to table 3 formula configuration embodiment 2-6, comparative example 5:

[0102] Table 3 (percentages in the form are percentages by weight)

[0103]

[0104]

[0105] As can be seen from Table 3: the formula of comparative example 5 does not add carbomer, while the content of carbomer in examples 2-6 is respectively 0.1%, 0.5%, 0.8%, 1.0%, 1.1%, the solubility of the six groups of formulas The detectable concentration of zinc is basically the same, but with the increase of the amount of carbomer added in the formula, the astringency of the formula is continuously decreasing, but when the added amount reaches 0.8%, the downward trend is obviously slowed down. Moreover, it was found in the paste preparation process that when the formula carbomer was added in an amount greater than 1.1%, the agitation of the paddle encountered resistance that was difficult to overcome, and the paste was not easy to pack and extrude in the later stage.

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Abstract

The invention discloses an oral care composition and application. The oral care composition comprises 1) soluble zinc, 2) carbomer and 3) an orally acceptable carrier, wherein the detectable concentration of the soluble zinc in the oral care composition is larger than or equal to 45 ppm. According to the oral care composition, the concentration of soluble zinc in the composition can be retained, and meanwhile, the unpleasant astringent taste of the soluble zinc is reduced, so that on one hand, the antibacterial effect of the composition is better exerted, and on the other hand, the use of thecomposition is not limited by the taste; and the composition can also effectively prolong the retention time of zinc in the oral cavity.

Description

technical field [0001] The invention relates to the technical field of oral care, in particular to an oral care composition and its application. Background technique [0002] Zinc ions, especially zinc ions in a soluble state, have good antibacterial effects and have a long history of application in the field of oral care. For example: Chinese patent application CN 102378627 A, titled "comprising 4-isopropyl-3 methylphenol and zinc ion antibacterial composition" discloses in the composition containing IPMP (4-isopropyl-3 methylphenol), zinc Combinations of ion sources and anionic surfactants enhance antibacterial activity; furthermore, the document finds that compositions comprising IPMPs have inherent anti-inflammatory activity, the activity of which is enhanced by the presence of a source of zinc ions. [0003] Chinese patent application CN 1649560A, titled "Antimicrobial Fresh Breath Oral Rinse", discloses a mouthwash containing CPC and zinc ions. It is antibacterial an...

Claims

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Application Information

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IPC IPC(8): A61K8/27A61K8/81A61Q11/00A61Q17/00
CPCA61K8/27A61K8/8147A61K8/8152A61Q11/00A61Q17/005
Inventor 谢森奎陈晓斌
Owner HAWLEY & HAZEL BVI
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