Cosmetic composition for increasing skin exfoliation
A technology of composition and cosmetics, which is applied in the direction of cosmetics, cosmetic preparations, dressing preparations, etc., and can solve the problems of reduced efficacy of keratin exfoliation
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Embodiment 1
[0058] Embodiment 1: evaluation of exfoliation of pigskin cuticle
[0059] According to the existing clinical evaluation method, it takes a long time, and it is difficult to conduct all experiments of various concentrations and pH conditions of various raw materials. In addition, because it is difficult to conduct experiments on all conditions of the composition composed of various raw materials, it is emerging The necessity of non-clinical keratinization evaluation method.
[0060] Therefore, the present invention uses the keratin exfoliation evaluation method mentioned in Journal of the European Academy of Dermatology and Venereology, 2014, 28, 415-423. In detail, the pig skin was biopsied and the materials to be tested were added. Thereafter, the amount of detached cutin was measured with a cell counter, and the sample put into water alone was shown as a negative control (0%), and 10% gluconolactone pH4 was shown as a positive control (100%).
[0061] (1) The experimental...
Embodiment 2
[0099] Example 2: Evaluation Method for Enhancement of Cutin Replacement Based on DHA Staining Method
[0100] The DHA hair dyeing method for evaluating the cutin turnover rate was carried out on 10 healthy males aged 20 to 40 using the method mentioned in Dermatology 1993, 186, 133-137. Before coating the sample, measure the lower arm of the experimenter's arm, the color of the inner side of the upper arm with a colorimeter (Chromameter), then dip the dihydroxyacetone of 10% concentration of about 0.4ml ( Dihydroxy acetone: DHA), and stick it on the inner side of the upper and lower arms for 8 hours. After 48 hours, the color of the part colored brown by DHA was measured to compare the color difference with that before the sample was applied. Thereafter, the sample was applied twice a day, and the degree of daily fading was measured with a colorimeter at the same time to measure the time required to return to the original skin color. TT (Turnover Time) 100% refers to the ti...
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