A microchannel hybrid catalytic hydrogenation device and method for preparing isophorol

Abstract

The invention discloses a microchannel mixed catalytic hydrogenation device and method for preparing isophorol. The device has a microchannel mixer and a hydrogenation reaction column connected in sequence, and the outlet of the hydrogenation reaction column is connected with a gas-liquid separation tank, the microchannel mixer is provided with two raw material inlets, one raw material inlet is a hydrogen feeding port, and the other raw material inlet is an isophorone feeding port, the raw material inlet of the hydrogenation reaction column is connected with the microchannel mixer The material outlet is connected, and the hydrogenation reaction column is filled with a hydrogenation catalyst; during preparation, the raw material hydrogen and isophorone flow into the microchannel mixer, and the isophorone and hydrogen are strongly mixed to form a The mixed fluid of the bubbles enters the hydrogenation reaction column for catalytic hydrogenation to obtain a liquid phase product containing isophorol, which is separated from the gas and liquid to obtain the isophorol product; the synthesis route of the present invention is simple, the reaction speed is fast, and the production cycle is short. Short, easy to operate, high yield, low cost, easy to industrial production.

Description

technical field [0001] The invention relates to the technical field of preparation methods of octocrylene, an ultraviolet absorber, in particular to a microchannel hybrid catalytic hydrogenation device and method for preparing isophorol. Background technique [0002] Isophorol, chemical name: 3,3,5-trimethylcyclohexanol, molecular formula: C 9 h 18 O, is a colorless oily liquid or solid, insoluble in water, soluble in organic solvents such as alcohols and hydrocarbons. It is an important intermediate for the synthesis of the ultraviolet absorber homosalate, and also an important intermediate for the synthesis of new plasticizers and lubricants. [0003] There are many reports on the synthesis of isophorol by isophorone reduction method, for example: J.Am.Chem.Soc.,1978,100(7):2226-2227; Tetrahedron,1980,36(13):1937- 1942; J.Org.Chem., 1986,51(10):1769-1773; Synth.Commun., 1988,18(1):89-96; Bull.Korean Chem.Soc., 2009,30(7) : 1588-1592 etc. have reported the chemical redu...

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Problems solved by technology

[0005] The problem to be solved by the present invention is: most of the catalytic hydrogenation reported at home and abroad are completed by intermittent hydrogenation tanks, the operation is cumbersome, frequent loading and unloading of catalysts is required, the hydrogen replacement is not complete, the reaction time is long, the efficiency is low, and the catalyst consumption is large. Poor safety and other issues, while the catalytic hydrogenation of the continuous process generally has a relatively large reaction volume and yield, which is not suitable for fine chemical and medical industries. There is a small contact area between the gas phase, liquid phase and the catalyst, and the efficiency of catalytic hydrogenation Low problem, the existing catalytic hydrogenation methods are not suitable for the process of isophorone catalytic hydrogenation to produce isophorol, and a microchannel mixed catalytic hydrogenation for preparing isophorol is provided Device and method

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