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Composition for preventing hair loss and nourishing scalp as well as preparation method and application of composition

A composition and scalp technology, applied in the composition of nourishing scalp, anti-hair loss field, can solve hair growth, itching, hair loss and other problems

Active Publication Date: 2021-03-16
HONGMEI PHARMA CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, the therapeutic effect of minoxidil is not achieved overnight, and long-term adherence to medication is required to achieve significant hair growth during use, and a rebound of hair loss will occur after stopping the drug for several months; and minoxidil may Drug allergic reaction, causing local itching and redness, etc.
The side effects of finasteride include gynecomastia, breast enlargement, breast tenderness, erectile dysfunction, testicular pain, abnormal ejaculation, etc. Long-term high-dose use can also weaken muscle strength and lead to osteoporosis, and it is prohibited to use Lactating and pregnant women; at the same time, the efficacy of finasteride in the treatment of hair loss is reversible, and patients need to take the drug for life. Once the drug is stopped, the patient's hair will continue or even intensify within 12 months.

Method used

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  • Composition for preventing hair loss and nourishing scalp as well as preparation method and application of composition
  • Composition for preventing hair loss and nourishing scalp as well as preparation method and application of composition
  • Composition for preventing hair loss and nourishing scalp as well as preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Embodiment 1 The preparation method of bovine spleen extract

[0077] The present embodiment provides a preparation method of bovine spleen extract, and the specific steps are as follows:

[0078] (1) get fresh and healthy bovine spleen 10kg, remove impurity and adipose tissue, obtain clean spleen, add the water homogenate of 8 times of spleen weight, obtain homogenate;

[0079] (2) heating the homogenate to 45°C, adjusting the pH value to 5.5, adding 1% by weight papain to keep in a water bath for 1.5h, and continuing to add 0.5% by weight 5'-phosphodiesterase for 2.5h;

[0080] (3) ultrasonically extracting the homogenate to obtain an extraction solution, wherein the ultrasonic extraction is ultrasonic extraction for 12 minutes under the conditions of a temperature of 55° C. and an ultrasonic power of 70W;

[0081] (4) Adjust the pH of the extract to 4.0, freeze at -20°C, thaw at 18°C, and freeze and thaw twice; the extract after the last thawing is centrifuged at 38...

Embodiment 2

[0085] Example 2 Anti-hair loss composition (1)

[0086] This embodiment provides an anti-hair loss composition, including bovine spleen extract, and a mixed extract of burdock and wild soybean seeds;

[0087] Among them, the raw materials and their weight ratios are as follows: 5 parts of bovine spleen, 2.5 parts of burdock, and 2.5 parts of wild soybean seeds.

[0088] The present embodiment further provides the preparation method of the above composition as follows:

[0089] (1) Mix and pulverize burdock and wild soybean seeds in a mass ratio of 1:1;

[0090] (2) Add water with an amount of 10 times the mass of the mixture to the pulverized mixture, soak for 1 hour, heat and decoct at 80°C for 2 times, extract for 2 hours each time and combine the two extracts, and then ultrasonically extract at 20 kHz. 0.5h;

[0091] (3) Centrifuge with a centrifuge for 30 minutes, control the centrifuge to be 4000 rpm, and filter the centrifuge twice with a Buchner funnel (the Buchner ...

Embodiment 3

[0093] Example 3 Anti-hair loss composition (2)

[0094] This embodiment provides an anti-hair loss composition, which is prepared from the following raw materials in parts by weight: 2.5 parts of bovine spleen, 5 parts of burdock, and 2.5 parts of wild soybean seeds.

[0095] The preparation method of the above composition is the same as that in Example 2, except that the mass ratio of burdock and wild soybean seeds in step (1) is 2:1.

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Abstract

The invention belongs to the field of traditional Chinese medicine compositions, and particularly relates to a composition for preventing hair loss and nourishing scalp as well as a preparation methodand application of the composition. The traditional Chinese medicine composition comprises a cattle spleen extract and a mixed extract of burdock and wild soybean seeds. The inventor finds that various bioactive substances with functions of preventing hair loss, nourishing and promoting hair growth in the traditional Chinese medicine composition can provide nutrient substances and promote hair growth starting from the internal environment and the external environment of hair growth; Besides, the scalp environment is protected, and good external conditions are provided for hair growth. Compared with common anti-hair-loss medicines (minoxidil, finasteride and the like), the traditional Chinese medicine composition provided by the invention has the advantages of smaller side effects and higher safety.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine compositions, and in particular relates to a composition for preventing hair loss and nourishing the scalp, and a preparation method and application thereof. Background technique [0002] With the development of society, people's life rhythm is getting faster and faster, bringing about such problems as irregular work and rest, high mental stress, insomnia, anxiety and so on. signs of youth. Clinical medicine has explained the causes of hair loss in many ways. The root cause is the atrophy and degeneration of hair follicles, and the hair no longer grows. At present, the most commonly used drugs in western medicine for the treatment of hair loss include minoxidil and finasteride. Although these drugs are effective, they have side effects. Among them, the therapeutic effect of minoxidil is not achieved overnight. In use, long-term adherence to medication is required to achieve obvious ha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P17/14A61P17/00A61K8/9789A61K8/98A61Q7/00A61Q5/12A61Q5/02A61K35/26
CPCA61K35/26A61K36/28A61K36/48A61P17/14A61P17/00A61K8/9789A61K8/981A61Q7/00A61Q5/12A61Q5/02A61K2800/5922A61K2800/82A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 郭智华徐双华田冉
Owner HONGMEI PHARMA CHINA
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