Hollow closed microneedle, preparation method thereof, and operating device comprising the microneedle
A closed, micro-needle technology, applied in the direction of micro-needles, needles, medical devices, etc., can solve the problems of complex structure and easy blockage of micro-needle devices
Active Publication Date: 2022-06-21
BEIHANG UNIV
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Problems solved by technology
[0004] This application solves the technical problem that the structure of the microneedle device in the prior art is complex and easy to block, and further provides a hollow closed microneedle with a simple structure, easy operation, and low risk of blockage. The present invention also provides the microneedle Needle preparation method and operating device including the microneedle
Method used
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Embodiment Construction
[0026] The “front” and “rear” in the directions involved in this embodiment are relative to the working process of the hollow closed microneedle. When the microneedle is implanted under the skin, the tip of the microneedle enters first. , the end that enters first is the front end, and the other end is the back end.
[0027] This embodiment provides a hollow closed microneedle, such as figure 1 As shown, a hollow closed microneedle is included. The hollow closed microneedle described in this embodiment is made of a degradable material, and the degradable material is a degradable magnesium alloy material.
[0028] The hollow closed microneedle described in this embodiment specifically includes the following components:
[0029] The main body of the microneedle is formed with a cavity for accommodating the medicine; the front end of the main body of the microneedle is in the shape of a tip; the outer diameter of the main body of the microneedle first increases gradually from th...
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Abstract
The present invention provides a hollow closed microneedle, which comprises the following components: a microneedle body with a cavity for containing medicine; the front end of the microneedle body is pointed; The outer diameter of the microneedle body first gradually increases from the front end to the tail end, and then gradually decreases; a barb structure is arranged on the outer surface of the microneedle body, and the barb structure is formed by the microneedle. The outer surface of the main body extends backward, and gradually inclines outward in the extending direction; the microneedle main body is provided with a detachable part, and the detachable part forms a seal to the cavity. The hollow closed microneedle of the present invention can transdermally transport liquid medicine; the degradable magnesium alloy material can be degraded in the skin; at the same time, it is provided with a barb structure, which can improve the skin adhesion of the microneedle.
Description
technical field [0001] The invention belongs to the technical field of percutaneous administration microneedle technology and micro-nano manufacturing process, and particularly relates to a hollow closed microneedle, a preparation method thereof, and an operating device comprising the microneedle. Background technique [0002] Microneedles refer to microneedle-like structures with a maximum length of less than 1 mm. It can be used to deliver drugs to or through the skin to the body, and because of its small size, microneedles can pierce the skin in a non-invasive and painless manner. In addition, microneedles can be integrated with microsensors and micropumps into a chip-sized experimental system for detecting diseases such as diabetes. More importantly, the route of delivering the drug to the body through the skin can avoid the metabolism of the drug by the liver and stomach, and the concentration and effect of the drug in the blood will be more stable. Numerous studies h...
Claims
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IPC IPC(8): A61M37/00C23C14/16C23C14/30C23C14/58
CPCA61M37/0015C23C14/30C23C14/16C23C14/5886A61M2037/0023A61M2037/003A61M2037/0046A61M2037/0053A61M2037/0061A61M2207/10
Inventor 王丽珍杜鑫王莹冯文韬姚杰樊瑜波
Owner BEIHANG UNIV