Application of Cbl-b protein in preparation of product with protective effect on lung injury induced by tobacco smoke

A protective effect, cbl-b technology, applied in the field of genetic engineering, can solve the problems such as the lack of Cbl-b and COPD research, to achieve the effect of protecting lung damage, reducing infiltration, and slowing down the decline of lung function
CN112717133APending Publication Date: 2021-04-30THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT)
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT)
Publication Date
2021-04-30

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Abstract

The invention discloses an application of Cbl-b protein in preparation of a product with a protective effect on lung injury induced by tobacco smoke. The product with a protective effect on lung injury induced by tobacco smoke is a medicine for promoting Cbl-b protein expression. The invention also discloses a medicine with the protective effect on lung injury induced by tobacco smoke, and the medicine is beneficial to protecting lung injury induced by tobacco smoke, slowing down the decline of lung function, reducing lung tissue macrophage and lymphocyte infiltration, relieving lung tissue inflammatory response, reducing the degree of emphysema; and slowing the epithelial-mesenchymal transition process of lung tissues.
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Description

technical field

[0001] The invention belongs to the technical field of genetic engineering, and specifically relates to the application of Cbl-b protein in the preparation of products with protective effect on lung damage induced by tobacco smoke. Background technique

[0002] Chronic obstructive pulmonary disease (COPD; COPD) is a respiratory disease characterized by chronic airway inflammation and emphysema, accompanied by progressive decline in lung function, which can seriously affect the quality of life of patients. High rates and mortality. In 2007, the prevalence rate of COPD in people over 40 years old in my country was as high as 8.2%, but it continued to increase to 13.7% in 2015. The number of COPD patients in my country has exceeded 99.9 million, which shows the rapid growth rate of the number of patients. The pathogenesis of COPD is closely related to smoking, air pollution, pathogen infection and other risk factors and genetic susceptibility factors. -Related...

Claims

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