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A kind of traditional Chinese medicine composition for gout and its preparation method and application

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve problems such as less side effects

Active Publication Date: 2022-05-10
INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the clinical treatment of gout has not been met so far, and the demand for drugs with good curative effect and few side effects is still very urgent.

Method used

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  • A kind of traditional Chinese medicine composition for gout and its preparation method and application
  • A kind of traditional Chinese medicine composition for gout and its preparation method and application

Examples

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Effect test

Embodiment 1

[0042] Embodiment 1 A kind of Chinese medicine composition for gout and the tablet prepared thereof

[0043] The traditional Chinese medicine composition for gout described in this embodiment consists of the following medicinal materials in parts by weight, wherein 1 part by weight=1kg:

[0044] 15 parts of Alisma, 12 parts of Plantago, 12 parts of Angelica dahurica, 12 parts of Chonglou, 5 parts of ephedra, 0.05 parts of menthol, 0.2 parts of borneol, and 3 parts of licorice.

[0045] According to the following method, the Chinese medicine composition is used as a raw material to prepare tablets:

[0046] 1) Prepare the raw materials and medicinal materials according to the ratio.

[0047]2) Grind menthol and borneol finely, pass through a 150-mesh sieve, and set aside.

[0048] 3) Take two-fifths of Chonglou and crush the ingredients into fine powder, pass through a 100-mesh sieve, and set aside.

[0049] 3) Take plantain seeds, licorice and the remaining three-flavored i...

Embodiment 2

[0052] Embodiment 2 A kind of Chinese medicine composition for gout and the capsule prepared thereof

[0053] The traditional Chinese medicine composition for gout described in this embodiment consists of the following medicinal materials in parts by weight, wherein 1 part by weight=1kg:

[0054] 20 parts of Alisma, 12 parts of Plantago, 12 parts of Angelica dahurica, 12 parts of Chonglou, 5 parts of ephedra, 0.5 parts of menthol, 3 parts of borneol, and 3 parts of licorice.

[0055] According to the following method, the Chinese medicine composition is used as a raw material to prepare tablets:

[0056] 1) Prepare the raw materials and medicinal materials according to the ratio.

[0057] 2) Grind menthol and borneol finely, pass through a 100-mesh sieve, and set aside.

[0058] 3) Take one-fifth of the medicinal materials of Chonglou and grind them into fine powder for later use.

[0059] 3) Take psyllium chrysanthemum and three flavors of licorice, add water to decoct and...

Embodiment 3

[0062] Embodiment 3 A kind of Chinese medicine composition for gout and the decoction prepared thereof

[0063] The traditional Chinese medicine composition for gout described in this embodiment consists of the following medicinal materials in parts by weight, wherein 1 part by weight=1g:

[0064] 22 parts of Alisma, 12 parts of Plantago, 12 parts of Angelica dahurica, 12 parts of Chonglou, 5 parts of ephedra, 0.05 parts of menthol, 0.2 parts of borneol, and 3 parts of licorice.

[0065] Prepare the raw materials according to the ratio; mix other medicinal materials except menthol, borneol and Angelica dahurica, and decoct them with water for 3 times, 40 minutes after each boiling, each time the amount of water added is 2 to 3 fingers higher than that of the medicinal materials; Filter and combine the filtrates. If the liquid medicine is too much, concentrate it appropriately, divide it into three parts, and take it within one day; divide the menthol and borneol into three par...

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Abstract

The invention relates to a traditional Chinese medicine composition for gout, comprising 10-35 parts of Alisma, 5-20 parts of Plantaginaceae, 5-20 parts of Angelica dahurica, 5-20 parts of Chonglou, 2-10 parts of Ephedra, and menthol 0.01‑1 part, borneol 0.05‑4 part, licorice 1‑10 part. The traditional Chinese medicine composition has a better uric acid-lowering effect on the zebrafish hyperuricemia model induced by potassium oxonate combined with xanthine.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for gout, a preparation method and application thereof. Background technique [0002] The occurrence of gout is directly related to hyperuricemia. Purine metabolism disorder and uric acid excretion disorder lead to urate formation and deposition in various parts of the body, causing acute and chronic inflammation and tissue damage with arthritis, gouty nephropathy, and tophi as the main clinical manifestations. Genetics, environment, dietary factors, metabolic disorders, and kidney diseases can cause disease alone or together. With changes in people's diet and lifestyle, the incidence of gout is increasing year by year, and the age of onset is getting younger. In addition to causing severe pain, joint deformities, and mobility impairments, gout can seriously reduce the quality of life of patients, and it can also cause gouty nephrop...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K9/30A61K9/48A61K9/08A61P19/06A61K31/045
CPCA61K36/884A61K36/68A61K36/232A61K36/896A61K36/17A61K31/045A61K36/484A61K9/282A61K9/4866A61K9/0095A61P19/06A61K2236/331A61K2236/333A61K2300/00
Inventor 王忠王永炎祁轶斐
Owner INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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