3D printing device of tissue compensation film for radiotherapy
A technology of tissue compensation and radiation therapy, applied in the field of medical devices, can solve the problem of insufficient target dose and achieve the effect of quantitative measurement structure
Inactive Publication Date: 2021-08-27
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AI-Extracted Technical Summary
Problems solved by technology
 Radiation therapy, as one of the main methods for treating tumor diseases, has been widely used clinically. The precise control of radiation therapy dose is very important in radiation therapy and is the core content of precision medicine. High-energy X (γ) rays and electron rays There is a dose build-up effect. The dose after the dose build-up area is the actual dose acting on the human body. One of the depth dose distribution characteristics of different energy rays is that the surface dose decreases with the increase of the ray energy. The depth of the maximum dose point and the percentage depth dose The depth from the surface to the maximum dose point is the dose build-up area, which causes the problem of insufficient target dose in the treatment of superficial lesions (such as breast cancer, skin cancer, et...
The right end inside of piston 507 is provided with cavity, and the left end of cavity is fixedly connected with water bag 511, and the inside of water bag 511 is provided with non-Newtonian liquid, and the right end of water bag 511 is fixedly connected with spring two 506, when piston 507 While moving left and right, because spring 2 506 will shake during stretching and compression, especially when the piston 507 passes through the pressure control tube 508, the shaking of spring 2 506 will be more severe, resulting in a sudden change in the pressure of the internal liquid , so that the pressure input into the liquid inlet pipe is unstable and affects the data collection effect. Through the water bag 511 arranged in the cavity of the piston 507, the characteristics of the non-Newtonian liquid inside the water bag 511 being strong when it is strong can be greatly improved. Buffer the shaking of the second spring 506, so that the liquid pressure in the piston box 505 remains ...
The invention discloses a 3D printing device of tissue compensation film for radiotherapy. The 3D printing device comprises a bottom plate and is characterized in that a positioning mechanism is fixedly connected to the upper end of the bottom plate, an air bag mechanism is fixedly connected to the lower end of the bottom plate, multiple sets of first through holes are formed in the middle of the bottom plate, and a detection mechanism is fixedly connected to the interiors of the first through holes. The top end of the detection mechanism is connected with a hydraulic mechanism through a pipeline, the positioning mechanism comprises a first positioning claw, a second positioning claw and a third positioning claw, the air bag mechanism comprises an air bag, an air inlet pipe is arranged on one side of the air bag, multiple sets of second through holes are formed in the middle of the air bag, and the lower ends of the second through holes are fixedly connected with the detection mechanism. The detection mechanism comprises an outer pipe, mercury is arranged on the side wall of the bottom of the outer pipe, a first spring is fixedly connected to the upper end of the outer pipe, and an inner pipe is movably connected to the interior of the first spring. According to the invention, the 3D printing device has the characteristics of high practicability and reduction of radiation on human body.
Additive manufacturing apparatusDiagnostic recording/measuring +2
PhysicsRadiotherapy treatment +3
- Experimental program(1)
 Next, the technical solutions in the embodiments of the present invention will be apparent from the embodiment of the present invention, and it is clearly described, and it is understood that the described embodiments are merely embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, there are all other embodiments obtained without making creative labor without making creative labor premises.
 See Figure 1-5 According to the present invention, the present invention provides a 3D printing apparatus for radiation therapy for tissue compensation films, including a bottom plate 1, characterized in that the upper end of the bottom plate 1 is fixedly connected to the positioning mechanism 2, and the lower end of the bottom plate 1 is fixedly connected to the airbag mechanism 3, A multi-set through hole is provided in the middle of the bottom plate 1, and the internal fixation of the through hole is fixed to the detection mechanism 4, and the tip end of the detecting mechanism 4 is connected to the hydraulic mechanism 5, and when the skin cancer patient is used, passed The positioning mechanism 2 is positioned in the surface of the human body, and the spatial coordinate system is established, using the adaptive characteristics of the airbag mechanism 3, collect the contour data of the skin surface of the disease, collect the skin of the disease through the detection function of the detection mechanism 4. The range data is transported by the hydraulic mechanism 5 to enter the detecting mechanism 4, and the tumor depth data is collected according to the tumor region and the non-tumor region absorbed by the patient's skin, and the tumor depth data is collected, and all collected data is depicted. In the established coordinate system, the purpose of determining the tumor distribution is achieved, and then the radiotherapy plan is made based on this tumor distribution. Three-dimensional profile data for tissue compensation films in the radiotherapy plan is obtained by dedicated 3D software, and the organization is produced by 3D printing. The mold of the membrane is compensated to obtain a personalized tissue compensation film;
 Location mechanism 2 includes positioning claws 201, positioning claws 2 202 and positioning claws three 203, reference Figure 5 When data acquisition is used to use the device, the device 2 is positioned in the surface of the human skin by the positioning mechanism 2, and the X-axis of the coordinate system is established by the connection of the claw one 201 and the positioning claw 2 202, and the positioning claw is defined. The direction of the 201 201 is the positive direction of the X-axis, and the direction of the position of the claws 3 203 is the positive direction of the Y-axis, and the direction of the Z-axis in the direction perpendicular to the XY plane is to establish a spatial coordinate system. The contact between the detecting mechanism 4 and the skin contact has a fixed position on the coordinate system, and various variables of the contacts can be described in the coordinate system to achieve the purpose of quantization measurement;
The airbag mechanism 3 includes an airbag 301, and an intake pipe 302 is provided on one side of the air bag 301, and a plurality of sets of through-hole two in the airbag 301 are provided. The lower end of the through hole two is fixed to the detecting mechanism 4, and when utilizing the device for patients with skin cancer When data acquisition is performed, the airbag 301 is in contact with the patient's skin, and the airbag 301 is inflated by the intake pipe 302. When the inflation is completed, the airbag 301 relies close contact with the skin surface, the surface of the contact is the contour of the patient. Since the detecting mechanism 4 is fixed to the airbag 301 by the through hole two, the acquired cases position profile will drive the high and low variation of the detecting mechanism 4, depicted the high and low changes of the detecting mechanism 4 in the coordinate system, It can be quantified to obtain the contour of the patient;
 The detecting mechanism 4 includes an outer tube 401, and the bottom side wall of the outer tube 401 is provided with mercury 407, and the upper end of the outer tube 401 is fixedly connected to the spring 125, and the inner activity of the spring 1205 is connected to the inner tube 402, the bottom end of the inner tube 402. The contact disk 406 is provided, and the upper end of the inner tube 402 is fixedly connected to the cover 403, and the top end of the cover 403 is fixedly connected to the liquid pipe 404, and the outer portion of the outer tube 401 is provided, and the skin cancer patient is performed using the device. When the acquisition, since the inner tube 402 of the detecting mechanism 4 is actively connected inside the outer tube 401, the contact disk 406 at the lower end of the inner tube 402 can be moved up and down as the compression and stretching of the spring 405, the contact disc 406 at the lower end of the inner tube 402 can also move up and down, when the airbag 301 Relying on its own adaptability to close contact with the skin surface, the contact disc 406 is also closely contacted with the skin of the patient, and is parallel to the lower end of the airbag 301, because the skin profile is irregular, resulting in the high and low of the contact tray 406, so that The upper end of the inner tube 402 is uneven, and the quantitative contour data of the patient's position is indirectly obtained by describing the high low position of the inner tube 402, indirectly obtains the temperature of the patient, and the contact disk 406 is in contact with the skin, since the temperature of the patient is high The temperature of the normal skin, so that the mercury 407 at the patient is thermally expanded, its height is significantly higher than that of the normal skin, thus judge where the patient is a patient position to determine the skin range of the disease;
 The hydraulic mechanism 5 includes a reservoir 501, an inner portion of the reservoir 501 is provided, and the hydraulic mechanism 5 includes a gearbox 502, a gearbox 502 and a reservoir 501 pipe connection, and the interior of the gearbox 502 is provided with a gear one. 503, the inner portion of the gearbox 502 is provided with gear 2 504, and the gear one 503 is engaged with the gear 2 504, and the hydraulic mechanism 5 includes a piston box 505, and the inner right side of the piston box 505 is fixedly connected to the spring 2 506, the left 506 left A piston 507 is provided, the left side fixed connection of the piston box 505, the pressure control tube 508 is connected to the reservoir 501 pipe, and the left side of the piston box 505 is fixedly connected to the liquid pipe 510, into the liquid pipe 510 Connect with the liquid pipe 404 pipe, the middle of the liquid pipe 510 is provided with a control valve, reference image 3 When the tumor size is collected by the device, the gear rotation and the gear two 504 are rotated counterclockwise through the gear tank 504, and the reservoir 501 is permeable, and the penetration proximity The pumping of the liquid, slowly enters the piston box 505, and pushes the piston 507 slowly moves to the left, while the spring 2 506 is tensioned, and when the piston moves to a certain extent, the access liquid tube 510, penetration proximity The liquid pipe 510 enters each of the liquid pipes 404, as the pumping proximity liquid is pumped, the piston 507 continues to the left, when the piston 507 exceeds the pressure control tube 508, because the pressure control tube 508 and the reservoir 501, At this time, the pressure inside the in-liquid pipe 510 remains unchanged. According to the Pasca principle, the amount of permeable proximity in each of the liquid pipes 404 is the same, then closing the control valve, at which time the infiltration of the injection within the liquid pipe 404 The affinity is entered into the skin surface through the contact plate 406 and slowly penetrates the inside of the skin, because tumor cells and normal cells absorb the efficiency of the absorption of osmosis proximity, and the absorption efficiency of tumor cells on the osmosis proximity It is much larger than normal cells, so in the specified period of time, the absorption of the osmosis proximity is different, and the remaining amount of each position to penetrate the proximity liquid is read through the scale on the outer tube 401, thereby obtaining an absorbent amount. Then compare the data of normal cells and tumor cells in the database, the depth of each position tumor can be calculated, and then the depth data of the tumor is depicted in the coordinate system, so that the tumor depth of each position can be quantified, when detected Reference Figure 4 , Rotate the gear one 503 clockwise, rotate the gear 2 504 counterclockwise, and open the control valve, at which time the penetration proximity is slowly pumped into the reservoir 501, the penetration proximity in each of the liquid pipes 404 is Under the action of the pressure, slowly returning to the piston box 505, as the permeability proximity is slowly pumped, the liquid in the piston box 505 slowly becomes less, the piston 507 recovers in water pressure and spring 2 506 Under the common action, slowly move to the right until it returns to the initial position to reach the purpose of repeated use of infiltration proximity;
 The piston box 505 is provided with a filter mechanism 6 in the middle of the in-liquid pipe 510, and the filter mechanism 6 includes a filter box 601, and a spring 3 603 is fixed at the bottom of the filter box 601. The top of the spring 3 603 is fixedly connected to the filter ball 602, the filter ball 602 A hole is provided. When the recovery is not used, the proximity is not used, because the permeability proximity liquid is in contact with the skin, it will carry a large amount of impurities, and the filter mechanism 6 is required in the middle of the piston box 505 and the liquid pipe 510, when recovery When the infiltration proximity is entered into the filter mechanism 6, the filterball 602 will block the pipe of the piston box 505, and the returning osmotic proximity liquid can only pass the filter talents. Enter the piston box 505, by providing a hole in the filter ball 602, the arranged holes can only pass the small particulate matter, thereby achieving the purpose of extracting large particulate impurities in the osmotic proximity liquid;
 The inside of the right end of the piston 507 is provided with a cavity, and the left end of the cavity is fixedly connected to the water space 511, and there is a nonewton liquid, and the right end of the water bag 511 is fixed to the spring 2 506, when the piston 507 is moving around While swaying during stretching and compression of the spring 2 506, in particular, when the piston 507 passes through the pressure control tube 508, the shake of the spring 2 506 will become more intense, resulting in mutations in the pressure of the internal liquid, so that The pressure of the input liquid tube is unstable, affecting the data collection effect, by setting the water bag 511 in the piston 507 cavity, the non-annion liquid inside the water bag 511 is strong, and the spring can be largely buffered. The shake of 506, so that the liquid pressure in the piston box 505 is stable, which is conducive to the stability of the acquisition of data;
 The gearbox 502 is fixedly connected to the two sets of brush mechanism 7, and the lower end of the gearbox 502 is fixedly connected with the filter. When the impurities in the recovered infiltration proximate, the impurities are not removed and entered into the gearbox 502, through the gear one 503 The meshing effect between the gear two 504 is ground, and the large particulate impurities in the osmosis procedure are grounded, and collecting the brush mechanism 7, and the impurities that are not fully collected are gathered at the bottom of the gearbox 502 because A filter is provided on the pipe of the reservoir 501, which can effectively prevent impurities from entering into the reservoir;
 The brush mechanism 7 includes a rotating shaft 701, and the rotation shaft 701 is fixed to the gearbox 502, and the outer portion of the rotation shaft 701 is fixedly coupled with a brush 702, and the brush 702 is provided with a brush plate 703, the internal setting of the brush 703. There is a hollow structure, and the surface near-axis end of the brush sheet 703 is provided with a plurality of sets of suction holes, and a steel wire is provided with a steel wire, and the gear is formed by meshing, penetration proximity liquid by meshing The large particle impurities are milled, partially adhered to the teeth of the gear one 503 and the gear two 504, and partially decreased in the liquid, and the bristle block is proximally adjacent to the brush mechanism 7, control the brush mechanism 7 in rotation. The shaft 701 is rotated in opposite directions, and when the wire is rotated to the wool of the brush 702, the impurities on the teeth are scraped by the steel wire, and enters the solution. Move together to the brush mechanism 7, when the impurity contacts the adsorbent hole on the brush 703, it is completely inhaled to the cavity of the brush 703, and as the hair brush mechanism 7 is rotated, inhalation to the brush piece 703 The impurities in the cavity are all concentrated on the top of the brush plate 703 under the action of centrifugation, since the top end of the brush plate 703 is closed, so that the impurities are collected at the top of the brush plate 703, thereby achieving the purpose of collecting impurities. ;
 The distance between any two sets of detecting mechanisms 4 is 2 mm, by providing the distance between any two sets of detection mechanisms 4 to be 2 mm to achieve the detection accuracy of the device.
 It should be noted that in this article, a relationship term such as the first and second, etc. is only used to separate an entity or operation with another entity or an operational area, without having to require or imply these entities or operations. There is any such practical relationship or order. Moreover, the term "comprising", "comprising" or any other variable is intended to encompass non-exclusive contained, so that the process, method, article, or device including a series of elements, not only those elements, but also not expressly listed. Other elements, or elements that are also inherent to this process, method, item, or device.
 It will be noted in that it is intended to be the preferred embodiment of the present invention as described above, and is not intended to limit the invention, although the foregoing examples have been described in detail, and those skilled in the art will still The technical solution described in the above examples can be modified or the equivalent replacement thereof is performed. Any modification, equivalent replacement, improvement, etc. according to the spirit of the invention should be included within the scope of the invention.
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