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Method and device for imaging magnetic resonance electromagnetic characteristic parameters of human body biological tissues

A technology of biological tissue and electromagnetic properties, which is applied in the direction of using nuclear magnetic resonance image system for measurement, magnetic resonance measurement, and magnetic variable measurement to achieve accurate inversion results

Active Publication Date: 2021-09-17
INST OF ELECTRICAL ENG CHINESE ACAD OF SCI
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Problems solved by technology

However, the existing perfusion functional MRI method does not quantitatively consider the distribution inversion and reconstruction of the permeability parameter itself from the perspective of tissue-electromagnetic field interaction like magnetic resonance-electrical property imaging.

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  • Method and device for imaging magnetic resonance electromagnetic characteristic parameters of human body biological tissues
  • Method and device for imaging magnetic resonance electromagnetic characteristic parameters of human body biological tissues
  • Method and device for imaging magnetic resonance electromagnetic characteristic parameters of human body biological tissues

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Embodiment approach

[0067] ① Starting from Ampere's law, deduce the calculation formulas of the receiving magnetic field and conductivity, permittivity and permeability, where conductivity and permittivity are jointly represented by the admittance, and the formula is specifically expressed by the gradient of the reciprocal of the admittance term, the reciprocal of the admittance and the constant term, that is, the formula of the convection-reaction equation. Substitute the aforementioned pure received magnetic field data into the admittance-based synchronous inversion formula to obtain the distributions of electrical and magnetic characteristic parameter values.

[0068] ② Starting from Faraday's modified Ampere's law, the relationship equation between the electrical and magnetic properties and the circularly polarized receiving magnetic field, which does not ignore the change of the magnetic permeability distribution, is derived. The conductivity and the permittivity are jointly represented by th...

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Abstract

The invention relates to a method and a device for imaging magnetic resonance electromagnetic characteristic parameters of human body biological tissues. The method comprises the following steps of respectively carrying out spin echo and proton density imaging sequence scanning to obtain image data, dividing the spin echo reconstruction image data by the proton density image data to obtain decoupled pure receiving magnetic field data, and on the basis of pure receiving magnetic field data, conducting synchronous reconstruction by utilizing a convection-reaction-diffusion or gradient indirect inversion algorithm to obtain parameter value distribution of the electrical conductivity, the dielectric constant and the magnetic conductivity of the tissue. A result obtained by utilizing the spin echo sequence and receiving magnetic field amplitude and phase component inversion does not contain contribution of quasi-static frequency components related to main magnetic field uniformity distortion in image data acquisition. The measurement process is noninvasive, and the obtained measured value does not need to be assisted by a contrast agent.

Description

technical field [0001] The present invention relates to an electromagnetic characteristic parameter imaging of human tissue based on magnetic resonance imaging, in particular to a functional magnetic resonance imaging method and device for simultaneous reconstruction of the electrical characteristic and magnetic characteristic parameter of brain tissue. Background technique [0002] Human tissue is an effective conductor of electromagnetic fields, and the physiological and pathological processes of the human body are also accompanied by changes in the electromagnetic field in the body. Using magnetic resonance electromagnetic properties imaging, the distribution of electrical and magnetic properties of brain tissue can be measured non-invasively. Because the hemoglobin molecules contained in blood have the characteristics of magnetic changes, blood can be detected by functional magnetic resonance imaging, magnetic properties-like magnetic resonance imaging and other methods....

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01R33/54
CPCG01R33/54Y02A90/30
Inventor 李晓南刘国强
Owner INST OF ELECTRICAL ENG CHINESE ACAD OF SCI
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