Magnesium alloy bone splint capable of resisting bacteria and inhibiting tumor proliferation and preparation method

A magnesium alloy, anti-tumor technology, applied in the direction of outer plate, internal bone synthesis, medical science, etc., can solve the problem of low strength, and achieve the effect of easy operation, excellent mechanical properties, and good antibacterial properties

Inactive Publication Date: 2021-09-24
INST OF MEDICINE & HEALTH GUANGDONG ACAD OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this method obtains an alloy in

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0039] Example 1

[0040] Step 1, remove scale and impurities on the surface of raw materials: use grinding wheels and sandpaper to grind scale and impurities on the surface of raw materials for pure magnesium ingots and master alloy ingots to obtain pure raw material blocks;

[0041] Step 2, weighing: according to weight percentage: Ag 0.1%, La 6%, Ca 0.4%, unavoidable impurity elements <0.01%, magnesium balance. Accurately weigh the raw materials for the preparation of the above-mentioned magnesium alloys. A hole is machined on the pure magnesium ingot, and its size is determined according to the size of the silver ingot particles. It is advisable to cover the hole with a machined piece of magnesium ingot to prevent the pure silver particles from falling;

[0042] Step 3, smelting and casting: place the weighed raw materials in the order of pure magnesium ingot, Mg-25% La master alloy ingot, Mg-25% Ca master alloy ingot and pure magnesium ingot with built-in pure silver parti...

Example Embodiment

[0046] Example 2

[0047] Step 1, remove scale and impurities on the surface of raw materials: use grinding wheels and sandpaper to grind scale and impurities on the surface of raw materials for pure magnesium ingots and master alloy ingots to obtain pure raw material blocks;

[0048] Step 2, weighing: according to weight percentage: Ag 0.2%, La 5%, Ca 0.5%, unavoidable impurity elements <0.01%, magnesium balance. Accurately weigh the raw materials for the preparation of the above-mentioned magnesium alloys. A hole is machined on the pure magnesium ingot, and its size is determined according to the size of the silver ingot particles. It is advisable to cover the hole with a machined piece of magnesium ingot to prevent the pure silver particles from falling;

[0049] Step 3, smelting and casting: place the weighed raw materials in the order of pure magnesium ingot, Mg-25% La master alloy ingot, Mg-25% Ca master alloy ingot and pure magnesium ingot with built-in pure silver par...

Example Embodiment

[0053] Example 3

[0054] Step 1, remove scale and impurities on the surface of raw materials: use grinding wheels and sandpaper to grind scale and impurities on the surface of raw materials for pure magnesium ingots and master alloy ingots to obtain pure raw material blocks;

[0055] Step 2, weighing: according to weight percentage: Ag 0.3%, La 4%, Ca 0.4%, unavoidable impurity elements <0.01%, magnesium balance. Accurately weigh the raw materials for the preparation of the above-mentioned magnesium alloys. A hole is machined on the pure magnesium ingot, and its size is determined according to the size of the silver ingot particles. It is advisable to cover the hole with a machined piece of magnesium ingot to prevent the pure silver particles from falling;

[0056] Step 3, smelting and casting: place the weighed raw materials in the order of pure magnesium ingot, Mg-25% La master alloy ingot, Mg-25% Ca master alloy ingot and pure magnesium ingot with built-in pure silver par...

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Abstract

The invention discloses a magnesium alloy bone splint capable of resisting bacteria and inhibiting tumor proliferation. The magnesium alloy bone splint comprises the following components in percentage by weight of 0.1-0.5% of Ag, 2-6% of La, 0.4-0.5% of Ca, less than 0.01% of inevitable impurity elements and the balance of magnesium, and the sum of the weight percentages of the components is 100%. The invention further discloses a preparation method of the magnesium alloy bone splint capable of resisting the bacteria and inhibiting the tumor proliferation. The method is specifically implemented according to the following steps of removing oxide skin and impurities on the surfaces of raw materials, weighing the raw materials with specified mass, and smelting to prepare a magnesium alloy ingot material; performing homogenizing heat treatment on the magnesium alloy ingot material; and preparing the magnesium alloy ingot material subjected to homogenizing heat treatment into a magnesium alloy plate through an extrusion process. The magnesium alloy bone splint has the characteristics of a good antibacterial property, capability of the inhibiting tumor proliferation and degradability.

Description

technical field [0001] The invention belongs to the technical field of biomedicine and alloy plates, relates to an antibacterial and anti-tumor growth-inhibiting magnesium alloy bone splint, and also relates to a preparation method of the antibacterial and anti-tumor growth-inhibiting magnesium alloy bone splint. Background technique [0002] In vivo biodegradable absorbent materials are a hotspot in the research of biomaterials. As the degree of aging increases and the number of patients with difficult diseases increases, the development of biomedical materials is becoming more and more important, and it has also attracted more and more attention from biomaterial researchers and medical workers. As early as the 1960s and 1970s, metal materials mainly made of titanium alloys and stainless steel, and ceramic materials mainly made of alumina and zirconia had been officially entered into clinical practice as medical materials and applied to the human body. Common properties of...

Claims

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Application Information

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IPC IPC(8): C22C23/06C22C1/03C22F1/06A61B17/80
CPCC22C23/06C22C1/03C22F1/06A61B17/80A61B2017/00526
Inventor 赵瑞芳徐春杰叶柯柯张凯军张忠明黄安卓李杰林舜生郭昱雍梁欣航
Owner INST OF MEDICINE & HEALTH GUANGDONG ACAD OF SCI
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