Medicine for treating ulcerative colitis and application of fullerene as active component

A technology for ulcerative colitis and active components, which is applied in the field of application of drugs for the treatment of ulcerative colitis and fullerenes as its active components, and can solve problems such as limited relief effect

Pending Publication Date: 2021-10-01
XIAMEN FUNANO NEW MATERIAL TECH COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the defects that the existing common medicines for treating ulcerative colitis can only alleviate the symptoms of ulcerative colitis and have limited relie

Method used

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  • Medicine for treating ulcerative colitis and application of fullerene as active component
  • Medicine for treating ulcerative colitis and application of fullerene as active component
  • Medicine for treating ulcerative colitis and application of fullerene as active component

Examples

Experimental program
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Effect test

Embodiment 1

[0039] Embodiment 1: A kind of preparation method of fullerene microcapsule powder

[0040] S1, olive oil, linseed oil, Xanthania sorbifolium oil are prepared nutritional compound oil according to the volume ratio of 5:3:2;

[0041] S2, 2.5g fullerene C 60 Dissolve in 1L nutrient compound oil after sterilization to form a compound oil complex;

[0042] S3, dissolving 10g of sodium caseinate, 5g of dipotassium hydrogen phosphate, and 15g of mono- and diglyceride fatty acid esters into the compound oil compound to obtain an oil phase;

[0043] S4. Dissolving 473g of maltodextrin in 1L of hot water at 80°C to obtain an aqueous phase;

[0044] S5, mixing and stirring the obtained water phase and the oil phase evenly, and then sterilizing;

[0045] S6. Homogenizing and spray-drying to obtain fullerene microcapsule powder, the content of fullerene in the fullerene microcapsule powder is 0.25wt%, and the particle diameter of the fullerene microcapsule powder is 20-500 μm.

Embodiment 2

[0046] Embodiment 2: a kind of preparation method of fullerene compound oil

[0047] Fullerene C 60 Disperse in olive oil, linseed oil, sorbifolium oil in a 5:3:2 volume ratio to obtain a mixed solution, the mixed solution is ball milled or ultrasonically centrifuged and filtered in turn, and the filtrate is collected The fullerene compound oil can be obtained, and the fullerene content in the fullerene compound oil is 0.5 wt%.

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Abstract

The invention belongs to the technical field of medicines, and relates to a medicine for treating ulcerative colitis and application of fullerene as an active component of the medicine. The medicine for treating ulcerative colitis contains fullerene and a medicine carrier. Researches show that the fullerene has a good prevention and treatment effect on ulcerative colitis, so that the fullerene can be used as an active component in the medicine for treating ulcerative colitis.

Description

technical field [0001] The invention belongs to the technical field of medicines, and relates to a medicine for treating ulcerative colitis and the application of fullerenes as its active components. Background technique [0002] Ulcerative colitis (UC) is a chronic nonspecific inflammatory bowel disease of unknown etiology. The clinical manifestations of UC are diarrhea, mucus pus and blood in the stool, abdominal pain, and systemic clinical symptoms. UC is a global disease, but its incidence has obvious regional differences. In Eastern Europe, Asia (including China) and developing countries, the incidence of ulcerative colitis was low in the past, but it has shown an obvious upward trend in recent years. It often occurs in young adults. In the UK, the first peak age of onset is 15-25 years old, and the second peak age is 55-65 years old. There is no significant difference in incidence between men and women. [0003] The exact etiology of UC is not yet clear, but mainly i...

Claims

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Application Information

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IPC IPC(8): A61K33/44A61P1/00A61P1/04
CPCA61K33/44A61P1/00A61P1/04
Inventor 高鹏举黎小青朱晟
Owner XIAMEN FUNANO NEW MATERIAL TECH COMPANY
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