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Application of traditional Chinese medicine composition and/or pharmaceutical preparation comprising the traditional Chinese medicine composition in the preparation of anti-inflammatory drugs or immunomodulatory drugs

An anti-inflammatory drug and composition technology, applied in the field of traditional Chinese medicine, can solve problems such as drug listing, and achieve the effects of treating abnormal immune function, prolonging life days, and increasing the number of inhibited cells

Active Publication Date: 2022-07-01
BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there are no related drugs on the market

Method used

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  • Application of traditional Chinese medicine composition and/or pharmaceutical preparation comprising the traditional Chinese medicine composition in the preparation of anti-inflammatory drugs or immunomodulatory drugs
  • Application of traditional Chinese medicine composition and/or pharmaceutical preparation comprising the traditional Chinese medicine composition in the preparation of anti-inflammatory drugs or immunomodulatory drugs
  • Application of traditional Chinese medicine composition and/or pharmaceutical preparation comprising the traditional Chinese medicine composition in the preparation of anti-inflammatory drugs or immunomodulatory drugs

Examples

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Effect test

Embodiment 1

[0071] This embodiment provides a traditional Chinese medicine composition, including 9 g of raw ephedra, 30 g of raw gypsum, 10 g of Bupleurum, 15 g of skullcap, 15 g of Artemisia annua, 10 g of bran fried Atractylodes, 30 g of verbena, 15 g of patchouli and 10 g of raw licorice.

[0072] The present embodiment also provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition. Extract the volatile oil for 2h, collect the volatile oil and set aside for use; the distilled water is collected in another container and set aside for later use; according to the prescribed amount, take raw ephedra, raw gypsum, Bupleurum, Scutellaria baicalensis, verbena and raw licorice and decocted with water for three times, add 10 Double the amount of water, decoct for 1h, add 8 times the amount of water for the second and third times, decoct for 0.5h each, combine the decoction liquid, filter, combine the filtrate with the above-mentioned distilled ...

Embodiment 2

[0074]This embodiment provides a traditional Chinese medicine composition, including 7 g of raw ephedra, 33 g of raw gypsum, 8 g of Bupleurum, 13 g of Scutellaria, 13 g of Artemisia annua, 13 g of Atractylodes Radix, 33 g of Verbena, 13 g of Huoxiang and 8 g of Licorice.

[0075] The present embodiment also provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition. The extraction time is 1h, and the volatile oil is collected and used for later use; the distilled water is collected in another container for later use; the raw ephedra, raw gypsum, Bupleurum, Scutellaria baicalensis, verbena and licorice are decocted three times with water according to the prescribed amount, and the first time is 20 times. measure water, decoct for 5h, add 3 times the amount of water for the second and third times, decoct each for 0.5h, combine the decoction liquid, filter, combine the filtrate with the above-mentioned distilled water, and concent...

Embodiment 3

[0077] This embodiment provides a traditional Chinese medicine composition, including 12 g of raw ephedra, 28 g of raw gypsum, 13 g of Bupleurum, 18 g of Scutellaria baicalensis, 18 g of Artemisia annua, 8 g of Atractylodes Rhizoma, 28 g of Verbena, 15 g of Huoxiang, and 13 g of Licorice.

[0078] The present embodiment also provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition. The extraction time is 3h, and the volatile oil is collected and used for subsequent use; the distilled water is collected in another container and used for later use; according to the prescription, take raw ephedra, raw gypsum, Bupleurum, Scutellaria baicalensis, verbena and licorice and decoct twice with water, and add 3 Double the amount of water, decoct for 0.5h, add 15 times the amount of water for the second time, decoct for 3h, combine the decoction liquid, filter, combine the filtrate with the above distilled water, and concentrate under re...

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Abstract

The present invention relates to the field of traditional Chinese medicine, and specifically provides the application of a traditional Chinese medicine composition and / or a pharmaceutical preparation comprising the traditional Chinese medicine composition in the preparation of inflammatory drugs or immunoregulatory drugs. It is obtained after optimizing the composition and content of the drugs in the compound formula. In the formula, ephedra, gypsum and Bupleurum are combined as the king drug; Scutellaria baicalensis, Artemisia annua, and Atractylodes are combined as the minister drugs; Verbena and Huoxiang are the adjuvant drugs; make medicine. The above-mentioned medicines have the functions of clearing away heat and detoxifying, dispelling lung and relieving asthma, and play a positive role in regulating the body's immunity, especially regulating the abnormal number of immune cells, making the number of immune cells return to normal, regulating the imbalance between pro-inflammatory factors and anti-inflammatory factors, so that the Restoring the balance of pro-inflammatory factors and anti-inflammatory factors, preventing and / or treating immune dysfunction and diseases caused by immune dysfunction.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to the application of a traditional Chinese medicine composition and / or a pharmaceutical preparation comprising the traditional Chinese medicinal composition in the preparation of anti-inflammatory drugs or immunoregulatory drugs. Background technique [0002] The body's immune system plays an important role in removing cancerous tissues and pathogenic bacteria, and cellular immunity is an important part of the body's immune system. In cellular immunity, lymphoid T cells and lymphoid B cells occupy a central position. Lymphoid T cells are mainly divided into CD8 cells according to different surface markers. + cytotoxic T cells, CD4 + helper T cells, CD4 + CD25 + of regulatory T cells, etc. Lymphoid B cells are mainly divided into CD45RB cells, B1 cells, B2 cells, etc. according to different surface markers. There are various cytokines expressed by lymphoid T cells an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/85A61P29/00A61P37/02A61K33/06
CPCA61K36/17A61K33/06A61K36/233A61K36/539A61K36/282A61K36/284A61K36/85A61K36/532A61K36/484A61P29/00A61P37/02A61K2236/331A61K2236/39A61K2236/51A61K2236/333A61K2300/00
Inventor 郭玉红崔煦然刘清泉
Owner BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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